Influenza a viruses control expression of proviral human p53 isoforms p53ß and δ133p53α

Journal of Virology

Volumn 86, Issue 16, 2012, Pages 8452-8460

  Terrier, Olivier ^a,b   Marcel, Virginie ^a   Cartet, Gaëlle ^b   Lane, David P ^c   Lina, Bruno ^b   Rosa Calatrava, Manuel ^b   Bourdon, Jean Christophe ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITÉ DE LYON   (France)

^c p53 Laboratory (p53Lab)   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

P53 ALPHA PROTEIN; P53 BETA PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENE PRODUCT; GENE SILENCING; HUMAN; HUMAN CELL; INFLUENZA A; INFLUENZA VIRUS A; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TRANSIENT EXPRESSION; VIRUS CELL INTERACTION; VIRUS REPLICATION;

CELL LINE; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS; INFLUENZA, HUMAN; PROTEIN ISOFORMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84865076768     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.07143-11     Document Type: Article

References (31)

1. Aoubala M, et al. 2011. p53 directly transactivatesΔ133p53α, regulating cell fate outcome in response to DNA damage. Cell Death Differ. 18:248-258.
2. Bourdon JC, et al. 2005. p53 isoforms can regulate p53 transcriptional activity. Genes Dev. 19:2122-2137.
3. Chen J, et al. 2009. p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev. 23:278-290.
4. Duchamp MB, et al. 2010. Pandemic A(H1N1)2009 influenza virus detection by real time RT-PCR: is viral quantification useful? Clin. Microbiol. Infect. 16:317-321.
5. Ehrhardt C, Ludwig S. 2009. A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway. Cell. Microbiol. 11:863-871.
6. Fujita K, et al. 2009. p53 isoforms delta133p53 and p53beta are endogenous regulators of replicative cellular senescence. Nat. Cell Biol. 11:1135-1142.
7. Josset L, Frobert E, Rosa-Calatrava M. 2008. Influenza A replication and host nuclear compartments: many changes and many questions. J. Clin. Virol. 43:381-390.
8. Josset L, et al. 2010. Gene expression signature-based screening identifies new broadlyeffectiveinfluenzaAantivirals.PLoSOne5(10):pii=e13169.doi:10.1371/ journal.pone.0013169.
9. Khoury MP, Bourdon JC. 2010. The isoforms of the p53 protein. Cold Spring Harb. Perspect. Biol. 2(3):a000927. doi:10.1101/cshperspect. a000927.
10. Levine AJ, Oren M. 2009. The first 30 years of p53: growing ever more complex. Nat. Rev. Cancer 9:749-758.
11. Lowy RJ. 2003. Influenza virus induction of apoptosis by intrinsic and extrinsic mechanisms. Int. Rev. Immunol. 22:425-449.
12. Ludwig S, Pleschka S, Planz O, Wolff T. 2006. Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells. Cell. Microbiol. 8:375-386.
13. Machado-Silva A, Perrier S, Bourdon JC. 2010. p53 family members in cancer diagnosis and treatment. Semin. Cancer Biol. 20:57-62.
14. Marcel V, et al. 2010. p53 regulates the transcription of its delta133p53 isoform through specific response elements contained within the TP53 P2 internal promoter. Oncogene 29:2691-2700.
15. Marcel V, et al. 2010. Delta160p53 is a novel N-terminal p53 isoform encoded by delta133p53 transcript. FEBS Lett. 584:4463-4468.
16. Marcel V, et al. 23 September 2011. Biological functions of p53 isoforms through evolution: lessons from animal and cellular models. Cell Death Differ. doi:10.1038/cdd.2011.120.
17. Marcel V, et al. 11 November 2011. Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity. Cell Death Differ. doi:10.1038/cdd.2011.152.
18. Moulès V, et al. 2011. Importance of viral genomic composition in modulating glycoprotein content on the surface of influenza virus particles. Virology 414:51-62.
19. Muñoz-Fontela C, et al. 2008. Transcriptional role of p53 in interferonmediated antiviral immunity. J. Exp. Med. 205:1929-1938.
20. Muñoz-Fontela C, et al. 2011. p53 serves as a host antiviral factor that enhances innate and adaptive immune responses to influenza A virus. J. Immunol. 187:6428-6436.
21. Palese P, Shaw M. 2007. Orthomyxoviridae: the viruses and their replication, p 1647-1689. In Knipe DM, et al (ed), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
22. Rohaly G, Korf K, Dehde S, Dornreiter I. 2010. Simian virus 40 activates ATR-delta p53 signaling to override cell cycle and DNA replication control. J. Virol. 84:10727-10747.
23. Schmittgen TD, Livak KJ. 2008. Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 3:1101-1108.
24. Shapira SD, et al. 2009. A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection. Cell 139:1255-1267.
25. Shen Y, et al. 2009. Influenza A virus induces p53 accumulation in a biphasic pattern. Biochem. Biophys. Res. Commun. 382:331-335.
26. Terrier O, et al. 2011. Cellular transcriptional profiling in human lung epithelial cells infected by different subtypes of influenza A viruses reveals an overall down-regulation of the host p53 pathway. Virol. J. 8:285.
27. Turpin E, et al. 2005. Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication. J. Virol. 79:8802-8811.
28. Wang X, et al. 2010. The non-structural (NS1) protein of influenza A virus associates with p53 and inhibits p53-mediated transcriptional activity and apoptosis. Biochem. Biophys. Res. Commun. 395:141-145.
29. Watanabe T, Watanabe S, Kawaoka Y. 2010. Cellular networks involved in the influenza virus life cycle. Cell Host Microbe 7:427-439.
30. Whiley DM, Sloots TP. 2005. A 5=-nuclease real-time reverse transcriptase-polymerase chain reaction assay for the detection of a broad range of influenza A subtypes, including H5N1. Diagn. Microbiol. Infect. Dis. 53: 335-337.
31. Zhirnov OP, Klenk HD. 2007. Control of apoptosis in influenza virusinfected cells by up-regulation of Akt and p53 signaling. Apoptosis 12: 1419-1432.