-
1
-
-
24944474877
-
Current management of brain metastases, with a focus on systemic options
-
Langer CJ, Mehta MP. Current management of brain metastases, with a focus on systemic options. J Clin Oncol 2005;23:6207-19.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6207-6219
-
-
Langer, C.J.1
Mehta, M.P.2
-
2
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002;346:92-8.
-
(2002)
N Engl J Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
Langer, C.4
Sandler, A.5
Krook, J.6
-
3
-
-
0036843105
-
Phase III randomized trial comparing three platinum-based doublets in advanced non-small-cell lung cancer
-
Scagliotti GV, De Marinis F, Rinaldi M, Crino L, Gridelli C, Ricci S, et al. Phase III randomized trial comparing three platinum-based doublets in advanced non-small-cell lung cancer. J Clin Oncol 2002;20:4285-91.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4285-4291
-
-
Scagliotti, G.V.1
De Marinis, F.2
Rinaldi, M.3
Crino, L.4
Gridelli, C.5
Ricci, S.6
-
4
-
-
34247101811
-
Risk of cerebral metastases and neurological death after pathological complete response to neoadjuvant therapy for locally advanced nonsmall-cell lung cancer: Clinical implications for the subsequent management of the brain
-
Chen AM, Jahan TM, Jablons DM, Garcia J, Larson DA. Risk of cerebral metastases and neurological death after pathological complete response to neoadjuvant therapy for locally advanced nonsmall-cell lung cancer: clinical implications for the subsequent management of the brain. Cancer 2007;109:1668-75.
-
(2007)
Cancer
, vol.109
, pp. 1668-1675
-
-
Chen, A.M.1
Jahan, T.M.2
Jablons, D.M.3
Garcia, J.4
Larson, D.A.5
-
5
-
-
20144368113
-
High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation
-
Mamon HJ, Yeap BY, Janne PA, Reblando J, Shrager S, Jaklitsch MT, et al. High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation. J Clin Oncol 2005;23:1530-7.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1530-1537
-
-
Mamon, H.J.1
Yeap, B.Y.2
Janne, P.A.3
Reblando, J.4
Shrager, S.5
Jaklitsch, M.T.6
-
6
-
-
80052622812
-
Tissue concentration of systemically administered antineoplastic agents in human brain tumors
-
Pitz MW, Desai A, Grossman SA, Blakeley JO. Tissue concentration of systemically administered antineoplastic agents in human brain tumors. J Neuro Oncol 2011;104:629-38.
-
(2011)
J Neuro Oncol
, vol.104
, pp. 629-638
-
-
Pitz, M.W.1
Desai, A.2
Grossman, S.A.3
Blakeley, J.O.4
-
7
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K, Sugawara S, Oizumi S, Isobe H, et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010;362:2380-8.
-
(2010)
N Engl J Med
, vol.362
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
Sugawara, S.4
Oizumi, S.5
Isobe, H.6
-
8
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, Tan EH, Hirsh V, Thongprasert S, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353:123-32.
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
Tan, E.H.4
Hirsh, V.5
Thongprasert, S.6
-
9
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
-
Mitsudomi T, Morita S, Yatabe Y, Negoro S, Okamoto I, Tsurutani J, et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol 2010;11:121-8.
-
(2010)
Lancet Oncol
, vol.11
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
Negoro, S.4
Okamoto, I.5
Tsurutani, J.6
-
10
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, Yang CH, Chu DT, Saijo N, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-57.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
Yang, C.H.4
Chu, D.T.5
Saijo, N.6
-
11
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou C, Wu YL, Chen G, Feng J, Liu XQ, Wang C, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011;12:735-42.
-
(2011)
Lancet Oncol
, vol.12
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
Feng, J.4
Liu, X.Q.5
Wang, C.6
-
12
-
-
84872830401
-
-
[cited September 5, 2011]. Available from
-
European Medicines Agency: Iressa: Gefitinib - EPAR summary for the public. [cited September 5, 2011]. Available from: http://www.ema.europa.eu/ docs/en-GB/document-library/EPAR--Summary-for-the-public/human/001016/ WC500036359.pdf.
-
Iressa: Gefitinib - EPAR Summary for the Public
-
-
-
13
-
-
84871351824
-
-
cited January 31, 2012
-
National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology. Non-small cell lung cancer. [cited January 31, 2012]. http://www.nccn.org/professionals/physician-gls/pdf/nscl.pdf.
-
Non-small Cell Lung Cancer
-
-
-
14
-
-
4143110253
-
Gefitinib in patients with brain metastases from non-small-cell lung cancer: A prospective trial
-
Ceresoli GL, Cappuzzo F, Gregorc V, Bartolini S, Crino L, Villa E. Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trial. Ann Oncol 2004;15:1042-7.
-
(2004)
Ann Oncol
, vol.15
, pp. 1042-1047
-
-
Ceresoli, G.L.1
Cappuzzo, F.2
Gregorc, V.3
Bartolini, S.4
Crino, L.5
Villa, E.6
-
15
-
-
79952268212
-
Brain metastases from lung cancer responding to erlotinib: The importance of EGFR mutation
-
Porta R, Sanchez-Torres JM, Paz-Ares L, Massuti B, Reguart N, Mayo C, et al. Brain metastases from lung cancer responding to erlotinib: the importance of EGFR mutation. Eur Respir J 2011;37:624-31.
-
(2011)
Eur Respir J
, vol.37
, pp. 624-631
-
-
Porta, R.1
Sanchez-Torres, J.M.2
Paz-Ares, L.3
Massuti, B.4
Reguart, N.5
Mayo, C.6
-
16
-
-
84856304068
-
"Pulsatile" high-dose weekly erlotinib for CNS metastases from EGFR mutant non-small cell lung cancer
-
Grommes C, Oxnard GR, Kris MG, Miller VA, Pao W, Holodny AI, et al. "Pulsatile" high-dose weekly erlotinib for CNS metastases from EGFR mutant non-small cell lung cancer. Neuro Oncol 2011;13:1364-9.
-
(2011)
Neuro Oncol
, vol.13
, pp. 1364-1369
-
-
Grommes, C.1
Oxnard, G.R.2
Kris, M.G.3
Miller, V.A.4
Pao, W.5
Holodny, A.I.6
-
17
-
-
33749046899
-
Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib
-
Jackman DM, Holmes AJ, Lindeman N, Wen PY, Kesari S, Borras AM, et al.Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib. J Clin Oncol 2006;24:4517-20.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4517-4520
-
-
Jackman, D.M.1
Holmes, A.J.2
Lindeman, N.3
Wen, P.Y.4
Kesari, S.5
Borras, A.M.6
-
18
-
-
78650390328
-
Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic EGFR mutations treated with gefitinib or erlotinib
-
Heon S, Yeap BY, Britt GJ, Costa DB, Rabin MS, Jackman DM, et al. Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic EGFR mutations treated with gefitinib or erlotinib. Clin Cancer Res 2010;16:5873-82.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5873-5882
-
-
Heon, S.1
Yeap, B.Y.2
Britt, G.J.3
Costa, D.B.4
Rabin, M.S.5
Jackman, D.M.6
-
19
-
-
45149084723
-
First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
-
Sequist LV, Martins RG, Spigel D, Grunberg SM, Spira A, Janne PA, et al. First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations. J Clin Oncol 2008;26:2442-9.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2442-2449
-
-
Sequist, L.V.1
Martins, R.G.2
Spigel, D.3
Grunberg, S.M.4
Spira, A.5
Janne, P.A.6
-
20
-
-
34548457234
-
The IASLC Lung Cancer Staging Project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours
-
Goldstraw P, Crowley J, Chansky K, Giroux DJ, Groome PA, Rami-Porta R, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2007;2:706-14.
-
(2007)
J Thorac Oncol
, vol.2
, pp. 706-714
-
-
Goldstraw, P.1
Crowley, J.2
Chansky, K.3
Giroux, D.J.4
Groome, P.A.5
Rami-Porta, R.6
-
21
-
-
58149234399
-
Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib
-
Costa DB, Nguyen KS, Cho BC, Sequist LV, Jackman DM, Riely GJ, et al. Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib. Clin Cancer Res 2008;14:7060-7.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7060-7067
-
-
Costa, D.B.1
Nguyen, K.S.2
Cho, B.C.3
Sequist, L.V.4
Jackman, D.M.5
Riely, G.J.6
-
22
-
-
33746034167
-
Exon 19 deletionmutations of epidermal growth factor receptor are associatedwith prolongedsurvival innon-small cell lung cancer patients treated with gefitinib or erlotinib
-
Jackman DM, Yeap BY, Sequist LV, Lindeman N, Holmes AJ, Joshi VA, et al. Exon 19 deletionmutations of epidermal growth factor receptor are associatedwith prolongedsurvival innon-small cell lung cancer patients treated with gefitinib or erlotinib. Clin Cancer Res 2006;12:3908-14.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3908-3914
-
-
Jackman, D.M.1
Yeap, B.Y.2
Sequist, L.V.3
Lindeman, N.4
Holmes, A.J.5
Joshi, V.A.6
-
23
-
-
76649134591
-
Phase II trial of erlotinib in chemotherapy-naive women with advanced pulmonary adenocarcinoma
-
suppl; abstr 8065
-
Jackman DM, Cioffredi LA, Lindeman N, Morse LK, Lucca J, Weckstein D, et al. Phase II trial of erlotinib in chemotherapy-naive women with advanced pulmonary adenocarcinoma. J Clin Oncol 27:15s, 2009 (suppl; abstr 8065).
-
(2009)
J Clin Oncol
, vol.27
-
-
Jackman, D.M.1
Cioffredi, L.A.2
Lindeman, N.3
Morse, L.K.4
Lucca, J.5
Weckstein, D.6
-
24
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
-
25
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, Gabriel S, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
26
-
-
32944468710
-
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening
-
Janne PA, Borras AM, Kuang Y, Rogers AM, Joshi VA, Liyanage H, et al. A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening. Clin Cancer Res 2006;12:751-8.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 751-758
-
-
Janne, P.A.1
Borras, A.M.2
Kuang, Y.3
Rogers, A.M.4
Joshi, V.A.5
Liyanage, H.6
-
27
-
-
74949110711
-
Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
-
Jackman D, Pao W, Riely GJ, Engelman JA, Kris MG, Janne PA, et al. Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. J Clin Oncol 2010;28:357-60.
-
(2010)
J Clin Oncol
, vol.28
, pp. 357-360
-
-
Jackman, D.1
Pao, W.2
Riely, G.J.3
Engelman, J.A.4
Kris, M.G.5
Janne, P.A.6
-
28
-
-
15744362912
-
The 2004 World Health Organization classification of lung tumors
-
Beasley MB, Brambilla E, Travis WD. The 2004 World Health Organization classification of lung tumors. Semin Roentgenol 2005;40:90-7.
-
(2005)
Semin Roentgenol
, vol.40
, pp. 90-97
-
-
Beasley, M.B.1
Brambilla, E.2
Travis, W.D.3
-
29
-
-
0000120995
-
A class of K-Sample tests for comparing the cumulative incidence of a competing risk
-
Gray RJ. A class of K-Sample tests for comparing the cumulative incidence of a competing risk. Ann Stat 1988;16:1141-54.
-
(1988)
Ann Stat
, vol.16
, pp. 1141-1154
-
-
Gray, R.J.1
-
30
-
-
1542532754
-
A Proportional Hazards Model for the Subdistribution of a Competing Risk
-
Jason PF, Gray RJ. A Proportional Hazards Model for the Subdistribution of a Competing Risk. J Am Stat Assoc 1999;94:496-509.
-
(1999)
J Am Stat Assoc
, vol.94
, pp. 496-509
-
-
Jason, P.F.1
Gray, R.J.2
-
31
-
-
84863892117
-
Randomized Phase II Trial of Erlotinib Alone or with Carboplatin and Paclitaxel in Patients Who Were Never or Light Former Smokers with Advanced Lung Adenocarcinoma: CALGB 30406 Trial
-
Janne PA, Wang X, Socinski MA, Crawford J, Stinchcombe TE, Gu L, et al. Randomized Phase II Trial of Erlotinib Alone or With Carboplatin and Paclitaxel in Patients Who Were Never or Light Former Smokers With Advanced Lung Adenocarcinoma: CALGB 30406 Trial. J Clin Oncol 2012;30:2063-9.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2063-2069
-
-
Janne, P.A.1
Wang, X.2
Socinski, M.A.3
Crawford, J.4
Stinchcombe, T.E.5
Gu, L.6
-
32
-
-
77954427100
-
Cerebrospinal fluid concentration of erlotinib and its active metabolite OSI-420 in patients with central nervous system metastases of non-small cell lung cancer
-
Togashi Y, Masago K, Fukudo M, Terada T, Fujita S, Irisa K, et al. Cerebrospinal fluid concentration of erlotinib and its active metabolite OSI-420 in patients with central nervous system metastases of non-small cell lung cancer. J Thorac Oncol 2010;5:950-5.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 950-955
-
-
Togashi, Y.1
Masago, K.2
Fukudo, M.3
Terada, T.4
Fujita, S.5
Irisa, K.6
-
33
-
-
66849118694
-
Dose escalation methods in phase I cancer clinical trials
-
Le Tourneau C, Lee JJ, Siu LL. Dose escalation methods in phase I cancer clinical trials. J Natl Cancer Inst 2009;101:708-20.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 708-720
-
-
Le Tourneau, C.1
Lee, J.J.2
Siu, L.L.3
-
34
-
-
70349758654
-
Activating mutations within the EGFR kinase domain: A molecular predictor of disease-free survival in resected pulmonary adenocarcinoma
-
Lee YJ, Park IK, Park MS, Choi HJ, Cho BC, Chung KY, et al. Activating mutations within the EGFR kinase domain: a molecular predictor of disease-free survival in resected pulmonary adenocarcinoma. J Cancer Res Clin Oncol 2009;135:1647-54.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, pp. 1647-1654
-
-
Lee, Y.J.1
Park, I.K.2
Park, M.S.3
Choi, H.J.4
Cho, B.C.5
Chung, K.Y.6
-
35
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, Maki RG, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.N Engl J Med 2010;363:1693-703.
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
Maki, R.G.6
-
36
-
-
80053386829
-
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
-
Shaw AT, Yeap BY, Solomon BJ, Riely GJ, Gainor J, Engelman JA, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol 2011;12:1004-12.
-
(2011)
Lancet Oncol
, vol.12
, pp. 1004-1012
-
-
Shaw, A.T.1
Yeap, B.Y.2
Solomon, B.J.3
Riely, G.J.4
Gainor, J.5
Engelman, J.A.6
-
37
-
-
79957487193
-
CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib
-
Costa DB, Kobayashi S, Pandya SS, Yeo WL, Shen Z, Tan W, et al.CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib. J Clin Oncol 2011;29:e443-5.
-
(2011)
J Clin Oncol
, vol.29
-
-
Costa, D.B.1
Kobayashi, S.2
Pandya, S.S.3
Yeo, W.L.4
Shen, Z.5
Tan, W.6
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