Resins and gums in historical iatrosophia texts from Cyprus-a botanical and medico-pharmacological approach

Frontiers in Pharmacology

Volumn JUL, Issue , 2011, Pages

  Lardos, Andreas ^a   Prieto Garcia, José ^a   Heinrich, Michael ^a,b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b SOUTHERN CROSS UNIVERSITY   (Australia)

Author keywords

Cyprus; Eastern mediterranean; Gums; Historical texts; Iatrosophia; Resins

Indexed keywords

ABIETIC ACID; AGAR WOOD; AMBER; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTINOCICEPTIVE AGENT; BENZOIN; BOSWELLIA CARTERI EXTRACT; CHERRY GUM; CISTUS CRETICUS EXTRACT; DIPYRONE; FRANKINCENSE; GUM ARABIC; INDOMETACIN; LADANUM; NATURAL PRODUCT; PINE RESIN; PINUS NIGRA EXTRACT; PLACEBO; PLANT EXTRACT; PLANT GUM; PLANT RESIN; PLUM GUM; PYCNOGENOL; SCAMMONY; SCLAREOL; SOLID STORAX; TURPENTINE; TURPENTINE OIL; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ADJUVANT ARTHRITIS; ALOPECIA; ARTICLE; BLADDER STONE; BOSWELLIA SERRATA; CHRONIC KIDNEY FAILURE; CISTUS; CISTUS CRETICUS; COUGHING; CYPRUS; DIARRHEA; DYSURIA; EAR EDEMA; ENTERITIS; ETHNOBOTANY; ETHNOPHARMACOLOGY; FEVER; GALBANUM; GALLSTONE; GOUT; HEMORRHOID; HERBAL MEDICINE; HISTORICAL PERIOD; HUMAN; MALARIA; MEDICAL LITERATURE; MEDICINAL PLANT; MICTURITION DISORDER; MINIMUM INHIBITORY CONCENTRATION; MORNING DOSAGE; NEPHROLITHIASIS; NOMENCLATURE; NONHUMAN; ORAL REHYDRATION THERAPY; OSTEOARTHRITIS; PAIN; PAW EDEMA; PHARMACOGNOSY; PHYTOCHEMISTRY; PHYTOTHERAPY; RHEUMATIC DISEASE; TRADITIONAL MEDICINE; WOUND INFECTION;

EID: 84865067417     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2011.00032     Document Type: Article

References (171)

1. Adams, M., Alther, W., Kessler, M., Kluge, M., and Hamburger, M. (2011). Malaria in the Renaissance: remedies from European herbals from the 16th and 17th century. J. Ethnopharmacol. 133, 278-288.
2. Adams, M., Berset, C., Kessler, M., and Hamburger, M. (2009). Medicinal herbs for the treatment of rheumatic disorders - a survey of European herbals from the 16th and 17th century. J. Ethnopharmacol. 121, 343-359.
3. Adams, F. (1844/1846/1847). The Seven Books of Paulus Aegineta. In three volumes. Translated from the Greek. With a commentary embracing the complete knowledge produced by the Greeks, Romans and Arabians on all subjects connected with medicine and surgery. London: Sydenham Society. Digital text, Bibliothèque Interuniversitaire de Medicine et d'Odontologie, Paris. Available at: http://web2.bium.univparis5.fr [last accessed 12/11/2010].
4. Ali, A. A., Ali, K. E., Fadlalla, A. E., and Khalid, K. E. (2008). The effects of gum arabic oral treatment on the metabolic profile of chronic renal failure patients under regular haemodialysis in Central Sudan. Nat. Prod. Res. 22, 12-21.
5. Ali, B. H., Ziada, A., and Blunden, G. (2009). Biological effects of gum arabic: a review of some recent research. Food Chem. Toxicol. 47, 1-8.
6. Aliotta, G., Piomelli, D., Pollio, A., and Touwaide, A. (2003). Le piante medicinali del Corpus Hippocraticum. Milano, Napoli: Angelo Guerini & Associati; Istituto italiano per gli studi filosofici.
7. Andrikopoulos, N. K., Kaliora, A. C., Assimopoulou, A. N., and Papapeorgiou, V. P. (2003). Biological activity of some naturally occurring resins, gums and pigments against in vitro LDL oxidation. Phytother. Res. 17, 501-507.
8. Arnold-Apostolides, N. (1985). Contribution à la connaissance ethnobotanique et médicinale de la flore de Chypre. Ph.D. thesis, Faculté de sciences pharmacologiques et biologiques, Université René Descartes de Paris, Luxembourg.
9. Banno, N., Akihisa, T., Yasukawa, K., Tokuda, H., Tabata, K., Nakamura, Y., Nishimura, R., Kimura, Y., and Suzuki, T. (2006). Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri. J. Ethnopharmacol. 107, 249-253.
10. Barrero, A. H. M., Arteaga, J., Akssira, M., Mellouki, F., Belgarrabe, A., and Blaquez, M. (2005). Chemical composition of the essential oils of Pistacia atlantica Desf. J. Essent. Oil Res. 17, 52-54.
11. Ben Amar, M. (2006). Cannabinoids in medicine: a review of their therapeutic potential. J. Ethnopharmacol. 105, 1-25.
12. Benabderrahmane, M., Benali, M., Aouissat, H., and Jordan Bueso, M.-J. (2009). Activite antimicrobienne des huiles essentielles de Pistacia atlantica Desf. de l'Algerie. Phytothérapie 7, 304-308.
13. Bennett, D. (2000). Medical practice in manuscripts in Byzantium. Soc. Hist. Med. 13, 279-291.
14. Berendes, J. (1902). Des Pendanius Dioscorides aus Anazarbos Arzneimittellehre in fünf Büchern. Stuttgart: Ferdinand Enke. Digital edition, Heilpflanzen-Welt, Bibliothek. Multi MED vision GbR Berliner Medizinredaktion, Medizin und Medien. Available at: http://buecher.heilpflanzen-welt.de/Dioskurides-Arzneimittellehre/ (accessed January 21, 2011).
15. Berger, F. (1964). Handbuch der Drogenkunde. Band VI. Balsame, Harze, Gummiharze, Gummi, Milchsäfte und Extrakte. Wien: Wilhelm Maudrich.
16. BGA (1978-1994). German Commission E Monographs. Bundes-Anzeiger, Bundesgesundheitsamt. Digital edition, Heilpflanzen-Welt, Bibliothek. Multi MED vision GbR Berliner Medizinredaktion, Medizin und Medien. Available at: http://buecher.heilpflanzen-welt.de/BGA-Commission-E-Monographs/ [accessed January 21, 2011].
17. Blain, E. J., Ali, A. Y., and Duance, V. C. (2010). Boswellia frereana (frankincense) suppresses cytokine-induced matrix metalloproteinase expression and production of pro-inflammatory molecules in articular cartilage. Phytother. Res. 24, 905-912.
18. Blaschek, W., Ebel, S., Hackenthal, E., Holzgrabe, U., Keller, K., Reichling, J., and Schulz., V. (2007). Hagers Enzyklopädie der Arzneistoffe und Drogen. Sechste (neu bearbeitete und ergänzte) Auflage. Stuttgart: Wissenschaftliche Verlagsgesellschaft and Springer.
19. Bloch, I. (1902). Byzantinische Medizin, in Handbuch der Geschichte der Medizin, eds. T. Puschmann, M. Neuburger, and J. Pagel (Jena: Fischer), 492-513.
20. Boer, E., and Ella, A. B. (2000). Plant Resources of South-East Asia. Leiden: Backhuys Publishers.
21. Bostock, J., and Riley, H. (1855). The Natural History. Pliny the Elder. London: Taylor and Francis. Digital edition, Perseus Digital Library Project, ed. G. R. Crane. Tufts University, Boston and Medford. Available at: http://www.perseus. tufts.edu/ [accessed January 14, 2011].
22. Bradley, P. (1992). British Herbal Compendium, Vol. 1. Bournemouth: British Herbal Medicine Association.
23. Bruce, M. (1970). John Sibthorp. Taxon 19, 353-362.
24. Bruneton, J. (1995). Pharmacognosy, Phytochemistry, Medicinal Plants. Hampshire: Intercept.
25. Brunton, L. L., Goodman, L. S., and Gilman, A. (2006). Goodman & Gilman's the pharmacological basis of therapeutics, 11th Edn. New York: McGraw-Hill.
26. Buenz, E. J., Bauer, B. A., Johnson, H. E., Tavana, G., Beekman, E. M., Frank, K. L., and Howe, C. L. (2006). Searching historical herbal texts for potential new drugs. BMJ 333, 1314-1315.
27. Buenz, E. J., Johnson, H. E., Beekman, E. M., Motley, T. J., and Bauer, B. A. (2005). Bioprospecting Rumphius's Ambonese Herbal: Volume I. J. Ethnopharmacol. 96, 57-70.
28. Buenz, E. J., Schnepple, D. J., Bauer, B. A., Elkin, P. L., Riddle, J. M., and Motley, T. J. (2004). Techniques: Bioprospecting historical herbal texts by hunting for new leads in old tomes. Trends Pharmacol. Sci. 25, 494-498.
29. Chrysanthis, K. (1940). Theriaka tis Kyprou. Kypriakai Spoudai. 39-63.
30. Chrysanthis, K. (1944). Ta aitia ton noson kata tous Kyprious. Kypriakai Spoudai H 83-97.
31. Chrysanthis, K. (1951). Ena kypriako iatrosophi. Kypriakai Spoudai IE.
32. Chrysanthis, K. (1966). Ena karamanlidiko kypriako iatrosophi. Kypriakai Spoudai 185-189.
33. Chrysanthis, K. (1988). Dimodis iatriki tis Kyprou symmeikta. Lefkosia (Nicosia): Iatrikou Syllogou Ippokratis.
34. Chrysanthis, K. (1942, ed. 1991). Kypriakes farmakeftikes yles sto peri ylis iatrikis tou Dioskouridi, in Apo tin istoria tis kypriakis iatrikis, ed. K. Chrysanthis (Nicosia: Politistikou Kentrou tis Laïkis Trapezas), 43-56.
35. Clark, P. A. (2002). Landscape, Memories, and Medicine: Traditional Healing in Amari, Crete. J. Mod. Greek Stud. 20, 339-365.
36. Codipilly, C. N., Teichberg, S., and Wapnir, R. A. (2006). Enhancement of Absorption by gum arabic in a model of gastrointestinal dysfunction. J. Am. Coll. Nutr. 25, 307-312.
37. Cordell, G. A., and Colvard, M. D. (2005). Some thoughts on the future of ethnopharmacology. J. Ethnopharmacol. 100, 5-14.
38. Council of the Pharmaceutical Society of Great Britain (1911). The British Pharmaceutical Codex. An Imperial Dispensatory for the use of Medical Practitioners and Pharmacists. London: The Pharmaceutical Press. Digital edition, ed. H. Kress (20012011), Henriette's Herbal Homepage. Available at: http://www.henriettesherbal.com/ [accessed February 13, 2011].
39. Cox, P. A. (1998). The promise of Gerard's Herball: new drugs from old books. Endeavour 22, 51-53.
40. Dawkins, R. M. (1936). The Semantics of Greek Names for Plants. J. Hellenic Stud. 56, 1-11.
41. Delaveau, P., Lallouette, P., and Tessier, A. M. (1980). Drogues végétales stimulant l'activité phagocytaire du système réticulo-endothélial. Planta Med. 40, 49-54.
42. Delazar, A., Reid, R. G., and Sarker, S. D. (2004). GC-MS analysis of the essential oil from the oleoresin of Pistacia atlantica var. mutica. Chem. Nat. Comp. 40, 24-27.
43. Della, A. (1999). The Cyprus Flora: in Checklist Format. Nicosia: International Plant Genetic Resources Institute & Agricultural Research Institute, Ministry of Agriculture, Natural Resources and Environment.
44. Demetzos, C., Dimas, K., Hatziantoniou, S., Anastasaki, T., and Angelopoulou, D. (2001). Cytotoxic and antiinflammatory activity of labdane and cis-clerodane type diterpenes. Planta Med. 67, 614-618.
45. Demetzos, C., Stahl, B., Anastassaki, T., Gazouli, M., Tzouvelekis, L. S., and Rallis, M. (1999). Chemical analysis and antimicrobial activity of the resin Ladano, of its essential oil and of the isolated compounds. Planta Med. 65, 76-78.
46. De-Vos, P. (2010). European materia medica in historical texts: longevity of a tradition and implications for future use. J. Ethnopharmacol. 132, 28-47.
47. Deutsche Apothekerschaft (1935, ed. 1953). Ergänzungsbuch zum Deutschen Arzneibuch, Erg. B. 6. 6. Ausgabe. Stuttgart: Deutscher Apotheker-Verlag.
48. Dietel, M., Dudenhausen Joachim W., and Suttorp, N. (2003). Harrisons Innere Medizin (English title: Harrison's principles of internal medicine). Berlin: ABW Wissenschaftsverlag.
49. ESCOP. (2009). ESCOP Monographs, Supplement to the 2nd Edn. Exeter: European Scientific Commitee on Phytotherapy.
50. Fan, A. Y., Lao, L., Zhang, R. X., Zhou, A. N., Wang, L. B., Moudgil, K. D., Lee, D. Y., Ma, Z. Z., Zhang, W. Y., and Berman, B. M. (2005). Effects of an acetone extract of Boswellia carterii Birdw. (Burseraceae) gum resin on adjuvant-induced arthritis in lewis rats. J. Ethnopharmacol. 101, 104-109.
51. Fernández, M. A., Tornos, M. P., García, M. D., De-las-Heras, B., Villar, A. M., and Sáenz, M. T. (2001). Antiinflammatory activity of abietic acid, a diterpene isolated from Pimenta racemosa var. grissea. J. Pharm. Pharmacol. 53, 867-872.
52. Filaretos. (1924-1925). Iatrosophikon, synachthen ypo tou skevophylakos tis en Kypro Ieras Monis Machaira, Mitrophanous 1790-1867. Lefkosia (Nicosia): Ekdosis Ieras Monis Machaira.
53. Fiore, C., Eisenhut, M., Ragazzi, E., Zanchin, G., and Armanini, D. (2005). A history of the therapeutic use of liquorice in Europe. J. Ethnopharmacol. 99, 317-324.
54. Flückiger, F. A., and Hanbury, D. (1874). Pharmacographia, A History of the Principal Drugs of Vegetable Origin met within Great Britain and British India. London: Macmillan and Co.
55. Fraas, C. (1845). Synopsis Plantarum Florae Classicae. München. E. A. Fleischmann.
56. Gennadios, P. G. (1914). Lexikon Phytologikon. Athens: Paraskeva Leoni.
57. Georgiadis, A. P. (1995). I istoria tis trelas stin Kypro kata tin tourkokratia kai anglokratia. Lefkosia (Nicosia): Private publication.
58. Gertsch, J. (2009). How scientific is the science in ethnopharmacology? Historical perspectives and epistemological problems. J. Ethnopharmacol. 122, 177-183.
59. Giner-Larza, E. M., Máñez, S., Giner, R. M., Recio, M. C., Prieto, J. M., CerdáNicolás, M., and Ríos, J. L. (2002). Anti-inflammatory triterpenes from Pistacia terebinthus galls. Planta Med. 68, 311-315.
60. Giner-Larza, E. M., Máñez, S., Giner-Pons, R. M., Carmen Recio, M., and Ríos, J. L. (2000). On the anti-inflammatory and anti-phospholipase A(2) activity of extracts from lanostane-rich species. J. Ethnopharmacol. 73, 61-69.
61. Giner-Larza, E. M., Máñez, S., Recio, M. C., Giner, R. M., Prieto, J. M., Cerdá-Nicolás, M., and Ríos, J. L. (2001). Oleanonic acid, a 3-oxotriterpene from Pistacia, inhibits leukotriene synthesis and has anti-inflammatory activity. Eur. J. Pharmacol. 428, 137-143.
62. Gonzalez-Tejero, M. R., Casares-Porcel, M., Sanchez-Rojas, C. P., RamiroGutierrez, J. M., Molero-Mesa, J., Pieroni, A., Giusti, M. E., Censorii, E., de Pasquale, C., Della, A., ParaskevaHadijchambi, D., Hadjichambis, A., Houmani, Z., El-Demerdash, M., El-Zayat, M., Hmamouchi, M., and Eljohrig, S. (2008). Medicinal plants in the Mediterranean area: synthesis of the results of the project Rubia. J. Ethnopharmacol. 116, 341-357.
63. Gören, A. C., Bilsel, G., Oztürk, A. H., and Topçu, G. (2010). Chemical composition of natural colophony from Pinus brutia and comparison with synthetic colophony. Nat. Prod. Commun. 5, 1729-1732.
64. Guest, E., and Al-Rawi, A. (1966). Flora of Iraq. Volume 1. Introduction to the Flora. Baghdad: Ministry of Agriculture of the Republic of Iraq.
65. Gülçin, I., Büyükokuroglu, M. E., Oktay, M., and Küfrevioglu, O. I. (2003). Antioxidant and analgesic activities of turpentine of Pinus nigra Arn. subsp. pallsiana (Lamb.) Holmboe. J. Ethnopharmacol. 86, 51-58.
66. Hadjichambis, A. Ch., ParaskevaHadjichambi, D., Della, A., Giusti, M. E., de Pasquale, C., Lenzarini, C., Censorii, E., Gonzales-Tejero, M. R., Sanchez-Rojas, C. P., RamiroGutierrez, J. M., Skoula, M., Johnson, C., Sarpaki, A., Hmamouchi, M., Jorhi, S., El-Demerdash, M., El-Zayat, M., and Pieroni, A. (2008). Wild and semidomesticated food plant consumption in seven circum-Mediterranean areas. Int. J. Food Sci. Nutr. 59, 383-414.
67. Hadjiioannou, K. (2000). Etymologiko lexiko tis omiloumenis kypriakis dialektou. Lefkosia (Nicosia): Tamasos. Ekdosi 2.
68. Hadjikyriakou, G. N. (2007). Aromatika kai artymatika fyta stin Kypro. Lefkosia (Nicosia): Politistiko Idryma Trapesis Kyprou.
69. Hanbury, D. (1857). On Storax. Science Papers, Chiefly Pharmacological and Botanical. 129-150.
70. Hanlidou, E., Karousou, R., Kleftoyanni, V., and Kokkini, S. (2004). The herbal market of Thessaloniki (N Greece) and its relation to the ethnobotanical tradition. J. Ethnopharmacol. 91, 281-299.
71. Hartwell, J. L. (1967). Plants used against cancer. A survey. Acanthaceae to Anacardiaceae. Lloydia 30, 379-405.
72. Heiberg, J. (1921/1924). Paulus Aegineta, 2 volumes. Corpus medicorum Graecorum 9.1 & 9.2. Leipzig: Teubner. Digital edition, TLG® (Thesaurus Linguae Graecae), University of California, Irvine. Available at: http:// www.tlg.uci.edu/ [accessed January 16, 2011].
73. Heinrich, M., Kufer, J., Leonti, M., and Pardo-de-Santayana, M. (2006). Ethnobotany and ethnopharmacology - interdisciplinary links with the historical sciences. J. Ethnopharmacol. 107, 157-160.
74. Hepper, F. N. (1987). Trees and shrubs yielding gums and resins in the ancient Near East. Bull. Sumer. Agri. 3, 107-114.
75. Heyd, W. (1879). Geschichte des Levantehandels im Mittelalter, Band 2. B) Alter südlicher Warenzug aus dem Orient ans Mittelmeer. Stuttgart: J.G. Cotta'schen Buchhandlung.
76. Hoekstra, J. H., Szajewska, H., Zikri, M. A., Micetic-Turk, D., Weizman, Z., Papadopoulou, A., Guarino, A., Dias, J. A., and Oostvogels, B. (2004). Oral rehydration solution containing a mixture of non-digestible carbohydrates in the treatment of acute diarrhea: a multicenter randomized placebo controlled study on behalf of the ESPGHAN working group on intestinal infections. J. Pediatr. Gastroenterol. Nutr. 39, 239-245.
77. Höfler, M. (1899). Deutsches Krankheitsnamen-Buch. München: Piloty & Loehle. Digital copy, Google books. Available at: http://books.google. com [accessed December 16, 2010].
78. Holland, B. K. (1994). Prospecting for drugs in ancient texts. Nature 369, 702.
79. Honda, G., Yeşilada, E., Tabata, M., Sezik, E., Fujita, T., Takeda, Y., Takaishi, Y., and Tanaka, T. (1996). Traditional medicine in Turkey. VI. Folk medicine in west Anatolia: Afyon, Kütahya, Denizli, Mugla, Aydin provinces. J. Ethnopharmacol. 53, 75-87.
80. Hovaneissian, M., Archier, P., Mathe, C., and Vieillescazes, C. (2006). Contribution de la chimie analytique à l'étude des exsudats végétaux styrax, storax et benjoin. C. R. Chimie 9, 1192-1202.
81. Howes, F. N. (1949). Vegetable Gums and Resins. Waltham: Chronica Botanica Company.
82. Howes, F. N. (1950). Age-old resins of the Mediterranean region and their uses. Econ. Bot. 4, 307-316.
83. Hunt, T. (1996). From plant lore to pharmacy: a prototype of the process, in Prospecting for drugs in ancient and medieval European texts: A scientific approach, ed. B. K. Holland (Amsterdam: Harwood Academic Publishers GmbH), 91-96.
84. Ince, I., Yesil-Celiktas, O., KarabayYavasoglu, N. U., and Elgin, G. (2009). Effects of Pinus brutia bark extract and Pycnogenol in a rat model of carrageenan induced inflammation. Phytomedicine 16, 1101-1104.
85. Ito, M., and Honda, G. (2005). Taxonomical identification of agarwood-producing species. Nat. Med. 59, 104-112.
86. Johns, T., and Sibeko, L. (2003). Pregnancy outcomes in women using herbal therapies. Birth Defects Res. B Dev. Reprod. Toxicol. 68, 501-504.
87. Kalpoutzakis, E., Chinou, I., Mitaku, S., Skaltsounis, A., and Harvala, C. (1998). Antibacterial labdane-type diterpenes from the resin ladano of Cistus creticus subsp. creticus. Nat. Prod. Lett. 11, 173-179.
88. Karageorghis, V. (1996). Some aspects of the maritime trade of Cyprus during the late Bronze age, in The development of the Cypriot economy, From the prehistoric period to the present day, eds V. Karageorghis and D. Michaelides (Nicosia: University of Cyprus & Bank of Cyprus), 61-67.
89. Kargotis, G. (1951). Dyo cherografa tis en Kypro Ieras Monis tis Panagias Machaira. Kypriakai Spoudai IE.
90. Kostoula, D. D. (1991). Agapios Landos, Geoponikon, Venetia 1643. Volos: Tinos.
91. Koureas, N. (2006). I iatriki stin Kypro kata to mesaiona, in H Iatriki stin Kypro - Apo tin Archaiotita mechri tin Anexartisia, ed. H. VryonidouYiangou (Nicosia: Politistiko Kentrou Omilou Laïkis), 101-149.
92. Kufer, J., Förther, H., Pöll, E., and Heinrich, M. (2005). Historical and modern medicinal plant uses - the example of the Ch'orti' Maya and Ladinos in Eastern Guatemala. J. Pharm. Pharmacol. 57, 1127-1152.
93. Kyprianou, C. S. (1987). Ergasies tou Kyprou Chrysanthi ston tomea tis laïkis iatrikis. Laografiki Kyprou 41-64.
94. Kyriazis. (1926). Kypriaka Chronika. Larnaka: Cheimonidi.
95. Langenheim, J. H. (2003). Plant resins. Chemistry, Evolution, Ecology, and Ethnobotany. Portland: Timber Press. Langkavel, B. (1866, reprint 1964). Botanik der späteren Griechen. Amsterdam: Adolf M. Hakkert.
96. Lardos, A. (2006). The botanical materia medica of the Iatrosophikon -a collection of prescriptions from a monastery in Cyprus. J. Ethnopharmacol. 104, 387-406.
97. Lemonica, I., Damasceno, D., and Di-Stasi L. C. (1996). Study of the embryotoxic effects of an extract of rosemary (Rosmarinus officinalis L.). Brazil. J. Med. Biol. Res. 29, 223-227.
98. Lentini, A. (2004). Fragrant substances and therapeutic compounds, in Pyrgos-Mavroraki, Advanced Technology in Bronze Age Cyprus, ed. M. R. Belgiorno (Nicosia: Archaeological Museum), 45-47.
99. Leonti, M. (2011). The future is written: Impact of scripts on the cognition, selection, knowledge and transmission of medicinal plant use and its implications for ethnobotany and ethnopharmacology. J. Ethnopharmacol. 134, 542-555.
100. Leonti, M., Cabras, S., Weckerle, C. S., Solinas, M. N., and Casu, L. (2010). The causal dependence of present plant knowledge on herbals - Contemporary medicinal plant use in Campania (Italy) compared to Matthioli (1568). J. Ethnopharmacol. 130, 379-391.
101. Leonti, M., Casu, L., Sanna, F., and Bonsignore, L. (2009). A comparison of medicinal plant use in Sardinia and Sicily-De Materia Medica revisited? J. Ethnopharmacol. 121, 255-267.
102. Lev, E. (2002). Reconstructed materia medica of the Medieval and Ottoman al-Sham. J. Ethnopharmacol. 80, 167-179.
103. Lev, E., and Amar, Z. (2002). Ethnopharmacological survey of traditional drugs sold in the Kingdom of Jordan. J. Ethnopharmacol. 82, 131-145.
104. Lev, E., and Amar, Z. (2008). Practical materia medica of the medieval Eastern Mediterranean according to the Cairo Genizah. Leiden: Brill.
105. Linares, E., and Bye, R. A. (1987). A study of four medicinal plant complexes of Mexico and adjacent United States. J. Ethnopharmacol. 19, 153-183.
106. List, P. H., Hörhammer, L., Kern, W., Roth, H. J., and Schmid, W. (1972). Hagers Handbuch der Pharmazeutischen Praxis. Vollständige (4.) Neuausgabe. Berlin, Heidelberg, New York: Springer.
107. López-Muñoz, F., Alamo, C., and GarcíaGarcía, P. (2006). The herbs that have the property of healing...: the phytotherapy in Don Quixote. J. Ethnopharmacol. 106, 429-441.
108. Lorente, I., Ocete, M. A., Zarzuelo, A., Cabo, M. M., and Jimenez, J. (1989). Bioactivity of the essential oil of Bupleurum fruticosum. J. Nat. Prod. 52, 267-272.
109. Maiga, A., Diallo, D., Fane, S., Sanogo, R., Paulsen, B. S., and Cisse, B. (2005). A survey of toxic plants on the market in the district of Bamako, Mali: traditional knowledge compared with a literature search of modern pharmacology and toxicology. J. Ethnopharmacol. 96, 183-193.
110. Mantell, C. L. (1949). The water-soluble gums - their botany, sources and utilization. Econ. Bot. 3, 1-31.
111. Marangou, A. G., and Georgiadis, A. P. (2006). I iatriki stin Kypro kata ti diarkeia tis anglokratias, in H Iatriki stin Kypro Apo tin Archaiotita mechri tin Anexartisia, ed. H. VryonidouYiangou (Nicosia: Politistiko Kentrou Omilou Laïkis), 217-398.
112. Martinez, D., Lohs, K., and Janzen, J. (1989). Weihrauch und Myrrhe. Kulturgeschichte und wirtschaftliche Bedeutung. Botanik - Chemie - Medizin. Stuttgart: Wissenschaftliche Verlagsgesellschaft.
113. Marzell, H., and Paul, H. (1979). Wörterbuch der deutschen Pflanzenamen. Vierter Band. Sabadilla-Zygophyllum. Stuttgart und Wiesbaden: S. Hirzel und Franz Steiner.
114. Meikle, R. (1977 and 1985). Flora of Cyprus, Vol. 1 and 2. Kew: The Bentham-Moxon Trust, Royal Botanical Gardens.
115. Mills, J., and White, R. (1989). The identity of the resins from the Late Bronze Age shipwreck at Ulu Burun (Kaş). Archaeometry 31, 37-44.
116. Mills, J., and White, R. (1994). The Organic Chemistry Of Museum Objects. Oxford: Butterworth-Heinemann.
117. Mochida, S., Ohno, A., Arai, M., Tamatani, T., Miyasaka, M., and Fujiwara, K. (1996). Role of adhesion molecules in the development of massive hepatic necrosis in rats. Hepatology 23, 320-328.
118. Moussaieff, A., and Mechoulam, R. (2009). Boswellia resin: from religious ceremonies to medical uses; a review of in-vitro, in-vivo and clinical trials. J. Pharm. Pharmacol. 61, 1281-1293.
119. Myrianthopoulos, K. I. (1925). Erymineftikos pinax tou iatrosophikou Machaira, in Iatrosophikon, synachthen ypo tou skevophylakos tis en Kypro Ieras Monis Machaira, Mitrophanous 1790-1867, ed. Filaretos (Nicosia: Ekdosis Ieras Monis Machaira), 165-191.
120. Nebel, S., Pieroni, A., and Heinrich, M. (2006). Ta chòrta: wild edible greens used in the Graecanic area in Calabria, Southern Italy. Appetite 47, 333-342.
121. Nussinovitch, A. (2010). Plant gum exudates of the world. Boca Raton: CRC Press, Taylor & Francis Group.
122. Ölker, P., and Direkçi, B. (2009). Mehmed Nidâî's Verse Medicine Treatise, Keyf-i Ki{dotless}tab-i{dotless} Ni{dotless}dai{dotless}. Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi 22, 295-305.
123. Panaretos, A. (1967). I chlorida tou topou mas. Nicosia: Pankyprios Enosis Geoponon, Pankyprios Enosis Geoponon.
124. Panaretos, A. (1979). I pissa tis Pafou. Laografiki Kypros 26, 53-54.
125. Papangellou, R. (2001). To kypriako idioma. Athens: Iolkos, Ekdosi A. Pardo-de-Santayana, M., Tardío, M., Heinrich, M., Touwaide, A., and Morales, R. (2006). Plants in the works of Cervantes. Econ. Bot. 60, 159-181.
126. Pereda-Miranda, R., Kaatz, G. W., and Gibbons, S. (2006). Polyacylated oligosaccharides from medicinal Mexican morning glory species as antibacterials and inhibitors of multidrug resistance in Staphylococcus aureus. J. Nat. Prod. 69, 406-409.
127. Petridis, G. (2000). Ta laografika. Lemesos (Limassol): Private publication.
128. Pharmacopoea Helvetica. (1933). Editio Quinta. Bern: Stämpfli & Cie.
129. Piomelli, D., and Pollio, A. (1994). Medicinal plants. Nature 371, 9.
130. Pollio, A., Natale, A. de, Appetiti, E., Aliotta, G., and Touwaide, A. (2008). Continuity and change in the Mediterranean medical tradition: Ruta spp. (rutaceae) in Hippocratic medicine and present practices. J. Ethnopharmacol. 116, 469-482.
131. Puschmann, T. (1878-1879). Alexander von Tralles. Original-Text und Übersetzung. Wien: Braumüller. Digital copy, Google books. Available at: http://book.google.com [accessed November 21, 2010].
132. Quintão, N. L., Da-Silva, G. F., Antonialli, C. S., Rocha, L. W., Cechinel-Filho, V., Cicció, J. F. (2010). Chemical composition and evaluation of the antihypernociceptive effect of the essential oil extracted from the leaves of Ugni myricoides on inflammatory and neuropathic models of pain in mice. Planta Med. 76, 1411-1418.
133. Raven, J., Lindsell, A., and Raven, F. (2000). Plants and Plant Lore in Ancient Greece. Oxford: Leopard's Head.
134. Remington, J. P., Woods, H. C. (1918). The Dispensatory of the United States of America, Botanicals Only, 20th Edn. Digital edition, ed. M. Moore (20032011), Henriette's Herbal Homepage. Available at: http://www.henriettesherbal.com/ [accessed February 13, 2011].
135. Richter, G. A. (1827). Ausführliche Arzneimittellehre. Handbuch für praktische Ärzte. Zweiter Band. Berlin: August Rücker.
136. Riddle, J. M. (1985). Dioscorides on Pharmacy and Medicine. Austin: Univ. of Texas Press.
137. Riddle, J. M. (1987). Recognition of Drugs in Classical Antiquity. Wisconsin: American Institute of the History of Pharmacy.
138. Riddle, J. M. (1992). Contraception and abortion from the ancient world to the Renaissance. Cambridge, MA: Harvard University Press.
139. Riddle, J. M. (1996). The medicines of Greco-Roman antiquity as a source of medicines for today, in Prospecting for Drugs in Ancient and Medieval European Texts: A Scientific Approach, ed. B. K. Holland (Amsterdam: Harwood Academic Publishers), 7-17.
140. Riddle, J. M. (2002). History as a tool in identifying new old drugs, in Flavonoids in Cell Function, ed. B. S. Buslig (New York: Kluwer Academic/ Plenum), 89-95.
141. Sadraei, H., Asghari, G. R., Hajhashemi, V., Kolagar, A., and Ebrahimi, M. (2001). Spasmolytic activity of essential oil and various extracts of Ferula gummosa Boiss. on ileum contractions. Phytomedicine 8, 370-376.
142. Scarborough, J. (1984). Early Byzantine pharmacology, in Symposium on Byzantine Medicine. Dumbarton Oaks Papers, Number Thirty-Eight, ed. J. Scarborough (Washington, DC: Dumbarton Oaks Research Library and Collection), 213-232.
143. Serpico, M. (2000). Resins, amber and bitumen, in Ancient Egyptian Materials and Technology, ed. P. T. Nicholson (Cambridge: Cambridge University Press), 432-474.
144. Sezik, E., Yeşilada, E., Honda, G., Takaishi, Y., Takeda, Y., and Tanaka, T. (2001). Traditional medicine in Turkey X. Folk medicine in Central Anatolia. J. Ethnopharmacol. 75, 95-115.
145. Spanopoulos, G. I. (1935). I laiki iatriki en Kypro. Nicosia: Chr. Nikolaos.
146. Stannard, J. (1984). Aspects of Byzantine materia medica, in Symposium on Byzantine Medicine. Dumbarton Oaks Papers, Number Thirty-Eight, ed. J. Scarborough (Washington DC: Dumbarton Oaks Research Library and Collection), 205-211.
147. Stavridis, T. (2006). I Iatriki stin Kypro kata tin Othomaniki Periodo, in H Iatriki stin Kypro - Apo tin Archaiotita mechri tin Anexartisia, ed. H. Vryonidou-Yiangou (Nicosia: Politistiko Kentrou Omilou Laïkis), 150-215.
148. Steppert, A. (1966). Die Therapie von Hautkrankheiten mit Mycopol. Wien. Med. Wochenschr. 116, 307-309.
149. Stevens, P. (2001). Angiosperm Phylogeny Website. Version 9, June 2008 (and more or less continuously updated since). Available at: http://www. mobot.org/MOBOT/research/ APweb/ [accessed November 06, 2010].
150. Stojkovic, D., Sokovicz, M., Glamoclija, J., Dzamic, A., Ristic, M., Fahal, A., Khalid, S., Djuic, I., and Petrovic, S. (2008). Suseceptibility of three clinical isolates of Actinomodura madurae to α-pinene, the bioactive agent of Pinus pinaster turpentine oil. Arch. Biol. Sci. Belgrade 60, 697-701.
151. Taila, S, Fiebich, B. L., Efferth, T., Beckwith, C., Prieto, J., and Heinrich, M. (2008). Anti-inflammatory and anti-oxidant activity of six Cistus species. J Pharm. Pharmacol. 60, A-62-A-63.
152. Teichberg, S., Wingertzahn, M. A., Moyse, J., and Wapnir, R. A. (1999). Effect of gum arabic in an oral rehydration solution on recovery from diarrhea in rats. J. Ped. Gastroenterol. Nutr. 29, 411-417.
153. Thiselton-Dyer, W. (1885). Notes on Cyprian drugs. Pharm. J. Trans. 3rd Series 15, 385-386.
154. Touwaide, A. (1992). The corpus of greek medical manuscripts: a computerized inventory and catalogue, in Tradizione e ecdotica dei test medici tardo-antichi e bizantini. Atti del Convegno internazionale, Anacapri, 29-31 ottobre 1990, ed. A. Garzya (Binghamton: The Harworth Press), 75-92.
155. Touwaide, A. (2007). Byzantine hospital manuals (iatrosophia) as a source for the study of therapeutics, in The Medieval Hospital and Medical Practice, ed. B. S. Bowers (Aldershot: Ashgate), 147-174.
156. Tschirch, A., and Stock, E. (1935/1936). Die Harze. Dritte und überarbeitete Auflage von Die Harze und die Harzbehälter. II. Band. Berlin: Gebrüder Bornträger.
157. Tschrich, A., and Lippmann, E. (1933). Allgemeine Phamakognosie. Dritte Abteilung. Leipzig: Bernhard Tauchnitz.
158. Tsintides, T., Hadjikyriakou, G. N., and Christodoulou, C. S. (2002). Trees and shrubs in Cyprus. Nicosia: Foundation Anastasios G. Leventis, Cyprus Forest Association.
159. Varella, E. A. (1995). Orientalische Elemente in der byzantinischen Heilkunde. Medicina nei Secoli. Arte e Scienza 7, 29-40.
160. Varella, E. A. (1999). La thérapeutique byzantine dans le monde grec d'epoque ottomane. Medicina nei Secoli. Arte e Scienza 11, 577-584.
161. Velephantou, K. (1913, ed. 1978). To Kyprianarion. Athens: Dyonisos.
162. Viney, D. (1994). An Illustrated Flora of North Cyprus. Koenigstein: Koeltz Scientific Books.
163. Wapnir, R. A., Wingertzahn, M. A., Moyse, J., and Teichber, S. (1997). Gum arabic promotes rat jejunal sodium and water absorption from oral rehydration solutions in two models of diarrhea. Gastroenterology 112, 1979-1985.
164. Warren, P. M. (2002). Cistus creticus L., in Sema Menelaou Parlama, eds T. Detorakis and A. Kalokairinos (Heraklion: Society for Cretan Historical Studies), 243-265.
165. Watt, J. M., and Breyer-Brandwijk, M. G. (1962). Medicinal and poisonous plants of South Africa, 2nd Edn. Edinburgh: E. and S. Livingstone Ltd.
166. Wellmann, M. (1906/1907/1914 (repr. 1958)). Pedanii Dioscuridis Anazarbei de materia medica libri quinque, 3 volumes. Berlin: Weidmann. Digital edition, TLG® (Thesaurus Linguae Graecae), University of California, Irvine. Available at: http://www.tlg.uci.edu/ [accessed January 16, 2011].
167. Williamson, E. (2003). Potter's Herbal Cyclopaedia. Saffron Walden: The C.W. Daniel Company Limited.
168. Wolff-Berlin, H. (1928). Die natürlichen Harze, in Monographien aus dem Gebiete der Fett-Chemie, ed. K. H. Bauer (Stuttgart: Wissenschaftliche Verlagsgesellschaft), 1-372.
169. Yam, J. (2007). The search for bioactive compounds in tropical plants to target hormone imbalance associated diseases. Ph.D. thesis, Basel: University of Basel, Faculty of Science.
170. Zeilinger, J. (1997). Cypern, Orient und Okzident. München: Matthes & Seitz. Zeybek, N. (1971). Liefert Styrax officinalis L. ein Harz? Bulletin de la Société Botanique Suisse 80, 189-193.
171. Zisper, B. (2009). John The Physician's Therapeutics. A Medical Handbook in Vernacular Greek. Leiden, Boston: Brill.