Prevalence and pattern of sexual dysfunction in married females receiving antidepressants: An exploratory study

Journal of Pharmacology and Pharmacotherapeutics

Volumn 3, Issue 3, 2012, Pages 259-265

  Grover, Sandeep ^a   Shah, Ruchita ^a   Dutt, Alakananda ^a   Avasthi, Ajit ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Antidepressants; depression; sexual dysfunction

Indexed keywords

ANTIDEPRESSANT AGENT; DULOXETINE; ESCITALOPRAM; FLUOXETINE; MIRTAZAPINE; PAROXETINE; SERTRALINE; VENLAFAXINE;

ADULT; ARTICLE; CONTROLLED STUDY; DEPRESSION; DYSPAREUNIA; EXPLORATORY RESEARCH; FEMALE; FEMALE SEXUAL DYSFUNCTION; FUNCTIONAL ASSESSMENT; HUMAN; LIBIDO DISORDER; MAJOR CLINICAL STUDY; ORGASM DISORDER; PATIENT ATTITUDE; SELF REPORT; SEXUAL AROUSAL; SEXUAL SATISFACTION; SOCIAL STATUS;

EID: 84865059000     PISSN: 0976500X     EISSN: None     Source Type: Journal    
DOI: 10.4103/0976-500X.99430     Document Type: Article

References (26)

1. Montejo AL, Llorca G, Tzquierdo JA, Rico-Villademoros F. Incidence of sexual dysfunction associated with antidepressant agents: A prospective multi-centre study of 1022 outpatients. J Clin Psychiatry 2001;62:10-22.
2. Montgomery SA, Baldwin DS, Riley A. Antidepressant medications: A review of the evidence for drug-induced sexual dysfunction. J Affect Disord 2002;69:119-40. (Pubitemid 34722878)
3. Kennedy SH, Eisfeld BS, Dickens SE, Bacchiochi JR, Bagby RM. Antidepressant-induced sexual dysfunction during treatment with moclobemide, paroxetine, sertraline, and venlafaxine. J Clin Psychiatry 2000;61:276-81. (Pubitemid 30305369)
4. Harrison WM, Rabkin JG, Ehrhardt AA, Stewart JW, McGrath PJ, Ross D, et al. Effects of antidepressant medication on sexual function: A controlled study. J Clin Psychopharmacol 1986;6:144-9. (Pubitemid 16021615)
5. Outhoff K. Antidepressant-induced sexual dysfunction. SA Fam Pract 2009;51:298-302.
6. Clayton AH, Pradko J, Croft H. Prevalence of sexual dysfunction among newer antidepressants. J Clin Psychiatry 2002;63:357-66. (Pubitemid 34456365)
7. Clayton AH, Montejo A. Major depressive disorder, antidepressants and sexual dysfunction. J Clin Psychiatry 2006;67:33-7. (Pubitemid 44078111)
8. Kennedy SH, Rizvi S, Fulton K, Rasmussen J. A double-blind comparison of sexual functioning, antidepressant efficacy, and tolerability between agomelatine and venlafaxine XR. J Clin Psychopharmacol 2008;28:329-33.
9. Zajecka J, Mitchell S, Fawcett J. Treatment-emergent changes in sexual function with selective serotonin reuptake inhibitors as measured with the Rush Sexual Inventory. Psychopharmacol Bull 1997;33:755-60. (Pubitemid 28128131)
10. Nagaraj AK, Nizamie SH, Akhtar S, Sinha BN, Goyal N. A comparative study of sexual dysfunction due to typical and atypical antipsychotics in remitted bipolar I disorder. Indian J Psychiatry 2004;46:261-6. (Pubitemid 40077047)
11. Nagaraj AK, Pai NB, Rao SA. Comparative study of sexual dysfunction involving risperidone, quetiapine, and olanzapine. Indian J Psychiatry 2009;51:265-71.
12. Nebhinani N, Grover S, Avasthi A. Sexual dysfunction in male subjects receiving trifluoperazine, risperidone and olanzapine: Does the prevalence vary with assessment questionnaire. Prim Care Companion CNS Disord 2012; 14:e1-e7.
13. Krishna K, Avasthi A, Grover S. Prevalence and psychological impact of Antidepressant associated sexual dysfunction: A study from North India. J Clin Psychopharmacology 2011;31:457-62.
14. Avasthi A, Kaur R, Prakash O, Banerjee A, Kumar L, Kulhara P. Sexual behavior of married young women: A preliminary study from North India. Indian J Comm Med 2008;33:163-7.
15. World Health Organization. The ICD-10 Classification of Mental and Behavioural Disorders-Clinical Description and Diagnostic Guidelines. Geneva: WHO; 1992.
16. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62.
17. Meston CM. Validation of the Female Sexual Function Index (FSFI) in Women with Female Orgasmic Disorder and in Women with Hypoactive Sexual Desire Disorder. J Sex Marital Ther 2003;29:39-46. (Pubitemid 36077807)
18. Wiegel M, Meston C, Rosen R. The Female Sexual Function Index (FSFI): Cross-validation and Development of Clinical Cutoff Scores. J Sex Marital Ther 2005;31:1-20. (Pubitemid 40070592)
19. Female Sexual Function Index [homepage on the Internet]. Bayer AG, Zonagen, Inc. and Target Health Inc.; © 2000 Available from: http://www. fsfiquestionnaire.com/. [Last cited on 2009 Mar 23].
20. Endicott J, Spitzer RL, Fleiss JL, Cohen J. The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 1976;33:766-71.
21. Moreira ED, Glasser DB, Nicolosi A, Duarte FG, Gingell C, GSSAB Investigators' Group. Sexual problems and help-seeking behaviour in adults in the United Kingdom and continental Europe. BJU Int 2008;101:1005-11. (Pubitemid 351422562)
22. Pollack MH, Reiter S, Hammerness P. Genitourinary and sexual adverse effects of psychotropic medication. Int J Psychiatry Med 1992;22:305-27. (Pubitemid 23084018)
23. Delgado P, Brannan S, Mallinckrodt C, Tran PV, McNamara RK, Wang F, et al. Sexual functioning assessed in 4 double-blind placebo-and paroxetinecontrolled trials of duloxetine for major depressive disorder. J Clin Psychiatry 2005;66:686-92. (Pubitemid 40942413)
24. Montejo-González AL, Llorca G, Izquierdo JA, Ledesma A, Bousoño M, Calcedo A, et al. SSRI-induced sexual dysfunction: Fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients. J Sex Marital Ther 1997;23:176-94. (Pubitemid 27514710)
25. Singh JC, Tharyan P, Kekre NS, Singh G, Gopalakrishnan G. Prevalence and risk factors for female sexual dysfunction in women attending a medical clinic in south India. J Postgrad Med 2009;55:113-20.
26. Berman JR, Berman L, Goldstein AI. Female sexual dysfunction: Incidence, pathophysiology, evaluation and treatment options. Urology 1999;54:385-91. (Pubitemid 29407007)