Small-molecule inhibitors of the protein methyltransferase SET7/9 identified in a high-throughput screen

Journal of Biomolecular Screening

Volumn 17, Issue 8, 2012, Pages 1102-1109

  Francis, Nicola Jane ^a,b   Rowlands, Martin ^a   Workman, Paul ^a   Jones, Keith ^a   Aherne, Wynne ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

compound screening; diversity set; FlashPlate; protein methyltransferases; SET7 9

Indexed keywords

119913 X; 610930 N; CCT 018324; CCT 021812; CCT 021895; CCT 038255; CCT 038257; METHYLTRANSFERASE; METHYLTRANSFERASE INHIBITOR; METHYLTRANSFERASE SET7 9; ORSEIN; RHODANINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME ACTIVITY; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; HISTONE METHYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SCINTILLATION;

ADENOSINE; CELL PROLIFERATION; ENZYME INHIBITORS; ETHIONINE; FLUOROIMMUNOASSAY; HCT116 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HISTONES; HUMANS; INHIBITORY CONCENTRATION 50; PROTEIN METHYLTRANSFERASES; SCINTILLATION COUNTING; SMALL MOLECULE LIBRARIES;

EID: 84864996744     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112452137     Document Type: Article

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