Multifocal motor neuropathy

Journal of Clinical Neuroscience

Volumn 19, Issue 9, 2012, Pages 1201-1209

  Muley, Suraj Ashok ^a   Parry, Gareth J ^b  

^a BARROW NEUROLOGICAL INSTITUTE   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Conduction block; Inflammatory neuropathy; Multifocal motor neuropathy

Indexed keywords

CYCLOPHOSPHAMIDE; GANGLIOSIDE GM1 ANTIBODY; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; PREDNISONE; RITUXIMAB; STEROID;

CLINICAL FEATURE; DEMYELINATION; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; ECHOGRAPHY; ELECTROMYOGRAPHY; FASCICULATION; HUMAN; LIMB WEAKNESS; MOTOR NERVE CONDUCTION; MOTOR NEUROPATHY; MUSCLE ACTION POTENTIAL; MYOKYMIA; NERVE BLOCK; NERVE FIBER; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROPATHY; PLASMAPHERESIS; PRIORITY JOURNAL; REVIEW; SENSORY NERVE CONDUCTION; UNSPECIFIED SIDE EFFECT; WEAKNESS;

ANTIBODIES, BLOCKING; ELECTROMYOGRAPHY; GANGLIOSIDES; HUMANS; MOTOR NEURON DISEASE; MOTOR NEURONS; MUSCLE WEAKNESS; NEURAL CONDUCTION; NEUROLOGIC EXAMINATION; POLYNEUROPATHIES; PROGNOSIS; SENSORY RECEPTOR CELLS;

EID: 84864977795     PISSN: 09675868     EISSN: 15322653     Source Type: Journal    
DOI: 10.1016/j.jocn.2012.02.011     Document Type: Review

References (83)

1. G.J. Parry, and S. Clarke Multifocal acquired demyelinating neuropathy masquerading as motor neuron disease Muscle Nerve 11 1988 103 107 (Pubitemid 18039607)
2. A.S. Pakiam, and G.J. Parry Multifocal motor neuropathy without overt conduction block Muscle Nerve 21 1998 243 245 (Pubitemid 28079746)
3. J.S. Katz, R.J. Barohn, and S. Kojan Axonal multifocal motor neuropathy without conduction block or other features of demyelination Neurology 58 2002 615 620 (Pubitemid 34164945)
4. E. Nobile-Orazio, A. Cappellari, and N. Meucci Multifocal motor neuropathy: clinical and immunological features and response to IVIg in relation to the presence and degree of motor conduction block J Neurol Neurosurg Psychiatry 72 2002 761 766 (Pubitemid 34557021)
5. E. Delmont, J.P. Azulay, and R. Giorgi Multifocal motor neuropathy with and without conduction block: a single entity? Neurology 67 2006 592 596 (Pubitemid 44273604)
6. M. Slee, A. Selvan, and M. Donaghy Multifocal motor neuropathy: the diagnostic spectrum and response to treatment Neurology 69 2007 1680 1687 (Pubitemid 350287124)
7. R.N. Auer, R.B. Bell, and M.A. Lee Neuropathy with onion bulb formations and pure motor manifestations Can J Neurol Sci 16 1989 194 197 (Pubitemid 19161247)
8. R. Kaji, N. Oka, and T. Tsuji Pathological findings at the site of conduction block in multifocal motor neuropathy Ann Neurol 33 1993 152 158 (Pubitemid 23039923)
9. R. Kaji, N. Hirota, and N. Oka Anti-GM1 antibodies and impaired blood-nerve barrier may interfere with remyelination in multifocal motor neuropathy Muscle Nerve 17 1994 108 110
10. A.M. Corse, V. Chaudhry, and T.O. Crawford Sensory nerve pathology in multifocal motor neuropathy Ann Neurol 39 1996 319 325 (Pubitemid 26100755)
11. B.V. Taylor, P.J. Dyck, and J. Engelstad Multifocal motor neuropathy: pathologic alterations at the site of conduction block J Neuropathol Exp Neurol 63 2004 129 137 (Pubitemid 38174778)
12. B.V. Taylor, B.A. Phillips, and B.R. Speed Serological evidence for infection with Campylobacter jejuni/coli in patients with multifocal motor neuropathy J Clin Neurosci 5 1998 33 35 (Pubitemid 128646481)
13. N.A. Sutedja, H.G. Otten, and E.A. Cats Increased frequency of HLA-DRB115 in patients with multifocal motor neuropathy Neurology 74 2010 828 832
14. M. Noguchi, K. Mori, and S. Yamazaki Multifocal motor neuropathy caused by a B-cell lymphoma producing a monoclonal IgM autoantibody against peripheral nerve myelin glycolipids GM1 and GD1b Br J Haematol 123 2003 600 605 (Pubitemid 37468055)
15. C. Rodriguez-Escalera, J. Belzunegui, and L. Lopez-Dominguez Multifocal motor neuropathy with conduction block in a patient with rheumatoid arthritis on infliximab therapy Rheumatology (Oxford) 44 2005 132 133 (Pubitemid 40124349)
16. B.V. Stern, J.M. Baehring, and K.A. Kleopa Multifocal motor neuropathy with conduction block associated with metastatic lymphoma of the nervous system J Neurooncol. 78 2006 81 84 (Pubitemid 43786664)
17. C.E. Barber, P. Lee, and A.H. Steinhart Multifocal motor neuropathy with conduction block following treatment with infliximab J Rheumatol 37 2010 1778 1780
18. S. Kelly, S. Connolly, and A. McCarthy PONM12 multifocal motor neuropathy due to infliximab J Neurol Neurosurg Psychiatry 81 2010 e63
19. A. Pestronk, D.R. Cornblath, and A.A. Ilyas A treatable multifocal motor neuropathy with antibodies to GM1 ganglioside Ann Neurol 24 1988 73 78
20. A. Jaspert, D. Claus, and H. Grehl Multifocal motor neuropathy: clinical and electrophysiological findings J Neurol 243 1996 684 692 (Pubitemid 26371924)
21. R.K. Olney, R.A. Lewis, and T.D. Putnam Consensus criteria for the diagnosis of multifocal motor neuropathy Muscle Nerve 27 2003 117 121 (Pubitemid 36083455)
22. J.T. Van Asseldonk, L.H. Van den Berg, and R.M. Van den Berg-Vos Demyelination and axonal loss in multifocal motor neuropathy: distribution and relation to weakness Brain 126 Pt 1 2003 186 198 (Pubitemid 36068569)
23. E.K. O'Ferrall, C.M. White, and D.W. Zochodne Demyelinating symmetric motor polyneuropathy with high titers of anti-GM1 antibodies Muscle Nerve 42 2010 604 608
24. P. Bouche, A. Moulonguet, and A.B. Younes-Chennoufi Multifocal motor neuropathy with conduction block: a study of 24 patients J Neurol Neurosurg Psychiatry 59 1995 38 44
25. V. Chaudhry, A.M. Corse, and D.R. Cornblath Multifocal motor neuropathy: electrodiagnostic features Muscle Nerve 17 1994 198 205 (Pubitemid 24040226)
26. E.A. Cats, W.L. van der Pol, and S. Piepers Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy Neurology 75 2010 818 825
27. B.V. Taylor, R.A. Wright, and C.M. Harper Natural history of 46 patients with multifocal motor neuropathy with conduction block Muscle Nerve 23 2000 900 908 (Pubitemid 30354497)
28. T. Kyriakides, S. Papacostas, and E. Papanicolaou Sleep hypoventilation syndrome and respiratory failure due to multifocal motor neuropathy with conduction block Muscle Nerve 43 2011 610 614
29. G. Axelsson, and L.J. Liedholm Multifocal motor neuropathy-unusual cause of hypoglossal palsy Lakartidningen 99 2002 1448 1450
30. D.C. Straver, J.T. van Asseldonk, and N.C. Notermans Cold paresis in multifocal motor neuropathy J Neurol 258 2011 212 217
31. G. Comi, S. Amadio, and G. Galardi Clinical and neurophysiological assessment of immunoglobulin therapy in five patients with multifocal motor neuropathy J Neurol Neurosurg Psychiatry 57 Suppl. 1994 35 37 (Pubitemid 24356104)
32. J.M. Leger, A.B. Younes-Chennoufi, and B. Chassande Human immunoglobulin treatment of multifocal motor neuropathy and polyneuropathy associated with monoclonal gammopathy J Neurol Neurosurg Psychiatry 57 Suppl. 1994 46 49 (Pubitemid 24356107)
33. R.M. Van den Berg-Vos, H. Franssen, and J.H. Wokke Multifocal motor neuropathy: long-term clinical and electrophysiological assessment of intravenous immunoglobulin maintenance treatment Brain 125 2002 1875 1886
34. M. Akaza, T. Kanouchi, and A. Inaba Motor nerve conduction study in cauda equina with high-voltage electrical stimulation in multifocal motor neuropathy and amyotrophic lateral sclerosis Muscle Nerve 43 2011 274 282
35. R. Arunachalam, A. Osei-Lah, and K.R. Mills Transcutaneous cervical root stimulation in the diagnosis of multifocal motor neuropathy with conduction block J Neurol Neurosurg Psychiatry 74 2003 1329 1331
36. C. Cappelen-Smith, S. Kuwabara, and C.S. Lin Abnormalities of axonal excitability are not generalized in early multifocal motor neuropathy Muscle Nerve 26 2002 769 776 (Pubitemid 35424426)
37. T. Yokota, Y. Saito, and N. Yuki Persistent increased threshold of electrical stimulation selective to motor nerve in multifocal motor neuropathy Muscle Nerve 19 1996 823 828 (Pubitemid 26190640)
38. J. Valls-Sole, A. Cruz Martinez, and F. Graus Abnormal sensory nerve conduction in multifocal demyelinating neuropathy with persistent conduction block Neurology 45 1995 2024 2028
39. C. Krarup, J.D. Stewart, and A.J. Sumner A syndrome of asymmetric limb weakness with motor conduction block Neurology 40 1990 118 127 (Pubitemid 20032904)
40. J.T. Van Asseldonk, L.H. Van den Berg, and S. Kalmijn Axon loss is an important determinant of weakness in multifocal motor neuropathy J Neurol Neurosurg Psychiatry 77 2006 743 747 (Pubitemid 43837201)
41. D.J. Lange, L.H. Weimer, and W. Trojaborg Multifocal motor neuropathy with conduction block: slow but not benign Arch Neurol 63 2006 1778 1781 (Pubitemid 44925088)
42. J.R. Daube Electrodiagnostic studies in amyotrophic lateral sclerosis and other motor neuron disorders Muscle Nerve 23 2000 1488 1502
43. R. Kaji, H. Bostock, and N. Kohara Activity-dependent conduction block in multifocal motor neuropathy Brain 23 2000 1602 1611 (Pubitemid 30481184)
44. S. Attarian, J.P. Azulay, and A. Verschueren Magnetic stimulation using a triple-stimulation technique in patients with multifocal neuropathy without conduction block Muscle Nerve 32 2005 710 714 (Pubitemid 41748277)
45. H. Nodera, H. Bostock, and Y. Izumi Activity-dependent conduction block in multifocal motor neuropathy: magnetic fatigue test Neurology 67 2006 280 287 (Pubitemid 44305413)
46. N. Deroide, D. Uzenot, and A. Verschueren Triple-stimulation technique in multifocal neuropathy with conduction block Muscle Nerve 35 2007 632 636 (Pubitemid 46676852)
47. D.C. Straver, L.H. van den Berg, and R.M. van den Berg-Vos Activity-dependent conduction block in multifocal motor neuropathy Muscle Nerve 43 2011 31 36
48. A. Pestronk, V. Chaudhry, and E.L. Feldman Lower motor neuron syndromes defined by patterns of weakness, nerve conduction abnormalities, and high titers of antiglycolipid antibodies Ann Neurol 27 1990 316 326 (Pubitemid 20122384)
49. E. Nobile-Orazio, M. Carpo, and G. Legname Anti-GM1 IgM antibodies in motor neuron disease and neuropathy Neurology 40 1990 1747 1750 (Pubitemid 20383144)
50. E. Nardelli, A.J. Steck, and T. Barkas Motor neuron syndrome and monoclonal IgM with antibody activity against gangliosides GM1 and GD1b Ann Neurol 23 1988 524 528
51. M.E. Shy, T. Heiman-Patterson, and G.J. Parry Lower motor neuron disease in a patient with autoantibodies against Gal(beta 1-3)GalNAc in gangliosides GM1 and GD1b: improvement following immunotherapy Neurology 40 1990 842 844 (Pubitemid 20159629)
52. A. Pestronk Invited review: motor neuropathies, motor neuron disorders, and antiglycolipid antibodies Muscle Nerve 14 1991 927 936
53. A. Pestronk, R.N. Adams, and L. Clawson Serum antibodies to GM1 ganglioside in amyotrophic lateral sclerosis Neurology 38 1988 1457 1461
54. A. Pestronk, R.N. Adams, and D. Cornblath Patterns of serum IgM antibodies to GM1 and GD1a gangliosides in amyotrophic lateral sclerosis Ann Neurol 25 1989 98 102 (Pubitemid 19032852)
55. M.E. Shy, V.A. Evans, and F.D. Lublin Antibodies to GM1 and GD1b in patients with motor neuron disease without plasma cell dyscrasia Ann Neurol 25 1989 511 513 (Pubitemid 19136685)
56. M. Roberts, H.J. Willison, and A. Vincent Multifocal motor neuropathy human sera block distal motor nerve conduction in mice Ann Neurol 38 1995 111 118
57. A. Uncini, M. Santoro, and M. Corbo Conduction abnormalities induced by sera of patients with multifocal motor neuropathy and anti-GM1 antibodies Muscle Nerve 16 1993 610 615 (Pubitemid 23157332)
58. G.K. Harvey, K.V. Toyka, and J. Zielasek Failure of anti-GM1 IgG or IgM to induce conduction block following intraneural transfer Muscle Nerve 18 1995 388 394
59. N. Yuki, H. Watanabe, and T. Nakajima IVIG blocks complement deposition mediated by anti-GM1 antibodies in multifocal motor neuropathy J Neurol Neurosurg Psychiatry 82 2011 87 91
60. G.J. Parry Antiganglioside antibodies do not necessarily play a role in multifocal motor neuropathy Muscle Nerve 17 1994 97 99 (Pubitemid 24012109)
61. R.M. Van den Berg-Vos, H. Franssen, and J.H. Wokke Multifocal motor neuropathy: diagnostic criteria that predict the response to immunoglobulin treatment Ann Neurol 48 2000 919 926
62. J.M. Leger, B. Chassande, and L. Musset Intravenous immunoglobulin therapy in multifocal motor neuropathy: a double-blind, placebo-controlled study Brain 124 Pt 1 2001 145 153 (Pubitemid 32055996)
63. H.W. Van Es, L.H. Van den Berg, and H. Franssen Magnetic resonance imaging of the brachial plexus in patients with multifocal motor neuropathy Neurology 48 1997 1218 1224 (Pubitemid 27240537)
64. R. Beekman, L.H. van den Berg, and H. Franssen Ultrasonography shows extensive nerve enlargements in multifocal motor neuropathy Neurology 65 2005 305 307 (Pubitemid 41022381)
65. E.L. Feldman, M.B. Bromberg, and J.W. Albers Immunosuppressive treatment in multifocal motor neuropathy Ann Neurol 30 1991 397 401
66. M. Carpo, A. Cappellari, and G. Mora Deterioration of multifocal motor neuropathy after plasma exchange Neurology 50 1998 1480 1482 (Pubitemid 28240378)
67. E. Delmont, J.P. Azulay, and D. Uzenot Long-term follow-up of multifocal motor neuropathy with conduction block under intravenous immunoglobulin Rev Neurol (Paris) 163 2007 82 88 (Pubitemid 46292063)
68. R.M. Van den Berg-Vos, H. Franssen, and J. Visser Disease severity in multifocal motor neuropathy and its association with the response to immunoglobulin treatment J Neurol 249 2002 330 336 (Pubitemid 34212277)
69. F. Terenghi, A. Cappellari, and A. Bersano How long is IVIg effective in multifocal motor neuropathy? Neurology 62 2004 666 668 (Pubitemid 38252820)
70. Cros D, Drake K. Multifocal motor neuropathies with conduction block: Long-term follow-up of ten patients treated with IVIg. Rev Neurol (Paris) 2006;162(Spec No 1):3S46-50. (Pubitemid 44663195)
71. P. Federico, D.W. Zochodne, and A.F. Hahn Multifocal motor neuropathy improved by IVIg: randomized, double-blind, placebo-controlled study Neurology 55 2000 1256 1262
72. E. Nobile-Orazio, N. Meucci, and S. Barbieri High-dose intravenous immunoglobulin therapy in multifocal motor neuropathy Neurology 43 1993 537 544 (Pubitemid 23088488)
73. J.M. Leger, K. Viala, and F. Cancalon Intravenous immunoglobulin as short- and long-term therapy of multifocal motor neuropathy: a retrospective study of response to IVIg and of its predictive criteria in 40 patients J Neurol Neurosurg Psychiatry 79 2008 93 96
74. V. Chaudhry, A.M. Corse, and D.R. Cornblath Multifocal motor neuropathy: response to human immune globulin Ann Neurol 33 1993 237 242 (Pubitemid 23081153)
75. T. Harbo, H. Andersen, and J. Jakobsen Long-term therapy with high doses of subcutaneous immunoglobulin in multifocal motor neuropathy Neurology 75 2010 1377 1380
76. P. Dacci, N. Riva, and M. Scarlato Subcutaneous immunoglobulin therapy for the treatment of multifocal motor neuropathy: a case report Neurol Sci 31 2010 829 831
77. T.H. Brannagan 3rd, A. Alaedini, and D.E. Gladstone High-dose cyclophosphamide without stem cell rescue for refractory multifocal motor neuropathy Muscle Nerve 34 2006 246 250 (Pubitemid 44167810)
78. S.J. Ruegg, P. Fuhr, and A.J. Steck Rituximab stabilizes multifocal motor neuropathy increasingly less responsive to IVIg Neurology 63 2004 2178 2179 (Pubitemid 39636279)
79. K. Stieglbauer, R. Topakian, and G. Hinterberger Beneficial effect of rituximab monotherapy in multifocal motor neuropathy Neuromuscul Disord 19 2009 473 475
80. V. Chaudhry, and D.R. Cornblath An open-label trial of rituximab (Rituxan(R)) in multifocal motor neuropathy J Peripher Nerv Syst 15 2010 196 201
81. P.J. Dyck, W.J. Johnson, and E.H. Lambert Segmental demyelination secondary to axonal degeneration in uremic neuropathy Mayo Clin Proc 46 1971 400 431
82. T. Ohi, R.A. Kyle, and P.J. Dyck Axonal attenuation and secondary segmental demyelination in myeloma neuropathies Ann Neurol 17 1985 255 261 (Pubitemid 15136599)
83. H. Nukada, and P.J. Dyck Acute ischemia causes axonal stasis, swelling, attenuation, and secondary demyelination Ann Neurol 22 1987 311 318 (Pubitemid 17137893)