Severe hemorrhage in a patient with metastatic colorectal cancer - Case 8/2012;Schwere Blutungen bei einer Patientin mit metastasierendem Kolonkarzinom - Fall 8/2012

Deutsche Medizinische Wochenschrift

Volumn 137, Issue 34-35, 2012, Pages

  Orgel M ^a   Horger, M ^a   Kurth, R ^a   Kanz, L ^a   Jaschonek, K ^a   Mayer, F ^a   Kopp, H G ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Colorectal cancer; Disseminated intravascular cogulation; Microangiopathic hemolysis

Indexed keywords

BLEEDING; COLORECTAL CANCER; HUMAN; REVIEW; AGED; ARTICLE; BLEEDING DISORDER; BONE MARROW; BONE MARROW CANCER; BRAIN TUMOR; CASE REPORT; COLON TUMOR; COMPUTER ASSISTED TOMOGRAPHY; DISEASE COURSE; DISSEMINATED INTRAVASCULAR CLOTTING; FATALITY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HEMATOMA; LIVER TUMOR; METASTASIS; PALLIATIVE THERAPY; PATHOLOGY; RETROPERITONEUM; THROMBOTIC THROMBOCYTOPENIC PURPURA; TUMOR EMBOLISM;

ANTINEOPLASTIC AGENT; CETUXIMAB; FLUOROURACIL; FOLINIC ACID; MONOCLONAL ANTIBODY; PLATINUM COMPLEX;

AGED; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE MARROW; BONE MARROW NEOPLASMS; BRAIN NEOPLASMS; DISEASE PROGRESSION; DISSEMINATED INTRAVASCULAR COAGULATION; FATAL OUTCOME; FEMALE; FLUOROURACIL; GASTROINTESTINAL HEMORRHAGE; HEMATOMA; HEMORRHAGIC DISORDERS; HUMANS; LEUCOVORIN; LIVER NEOPLASMS; NEOPLASTIC CELLS, CIRCULATING; ORGANOPLATINUM COMPOUNDS; PALLIATIVE CARE; PURPURA, THROMBOTIC THROMBOCYTOPENIC; RETROPERITONEAL SPACE; SIGMOID NEOPLASMS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84864936973     PISSN: 00120472     EISSN: 14394413     Source Type: Journal    
DOI: 10.1055/s-0032-1305227     Document Type: Review

References (18)

1. Robier C, Neubauer M, Beham-Schmid C et al. Thrombotic Microangiopathy and disseminated intravascular coagulation associated with carcinocythemia in a patient with breast cancer. J Clin Oncol 2011; 29:e825-826.
2. Arkenau HAT, Mssig O, Buhr T et al. Microangiopathic hemolytic anemia (MAHA) as paraneoplastic syndrome in metastsized signet ring cell carcinomas: case reports and review of the literature. Z Gastroenterol 2005; 43:719-722. (Pubitemid 41233459)
3. Dempke W, von Poblozki A, Kellner O et al. Hmorrhagische Diathese als Erstsymptom eines Magenkarzinoms. Wien Klin Wochenschr 2000; 112:1053-1058. (Pubitemid 32118770)
4. Bick RL. Coagulation abnormalities in malignancy: a review. Semin Thromb Hemost 1992; 18:353-372. (Pubitemid 23190616)
5. Sallah S, Wan JY, Nguyen NP et al. Disseminated intravascular coagulation in solid tumors: clinical and pathologic study. Thromb Haemost 2001; 86:828-833. (Pubitemid 32834193)
6. Caine GJ, Stonelake PS Lip GY et al. The hypercoagulable state of malignancy: pathogenesis and current debate. Neoplasia 2002; 4:465-473. (Pubitemid 35417069)
7. List C, Paramentier S, Jahn S et al. Infiltration des Knochenmarks und disseminierte intravasale Gerinnung. Seltene Erstsymptome eines soliden Tumors. Internist (Berl) 2011; 52:324-327.
8. Mytnik M, Stasko J. D-Dimer, plasminogen activator inhibitor-1, prothrombin fragments and protein C-role in prothrombotic state of colorectal cancer. Neoplasma 2011; 58:235-238.
9. Nand S, Messmore H. Hemostasis in malignancy. Am J Hematol 1990; 35:45-55. (Pubitemid 20254385)
10. Halamkova J, Kiss I, Tomasek J et al. Plasminogen activator system and its clinical significance in patients with a malignant disease. Klin Onkol 2011; 24:418-423.
11. Semeraro N, Colucci M. Tissue factor in heath and disease. Thromb Haemost 1997; 78:759-764.
12. Falanga A, Rickles FR. Pathophysiology of the thrombophilic state in the cancer patient. Semin Thromb Hemost 1999; 25:173-182. (Pubitemid 29227146)
13. Franchini M, Lippi G. Acquired von Willebrand yndrome: an update. Am J Hematol 2007; 82:368-375. (Pubitemid 46651140)
14. Wong KF, Chan JK, Ma SK. Solid tumour with initial presentiation in the bone marrow a clinicopathologic study of 25 adult cases. Hemtol Oncol 1993; 11:35-42. (Pubitemid 23192251)
15. Krauth MT, Puthenparambil J, Lechner K. Paraneoplastic autoimmune thrombocytopenia in solid tumors. Crit Rev Oncol Hematol 2012; 81:75-81.
16. Rhee J, Han SW, Oh DY et al. Clinicopathologic features and clinical outcomes of gastric cancer that initially presents with disseminated intravascular coagulation: a retrospective study. J Gastroenterol Hepatol 2010; 25:1537-1542.
17. Kopp HG, Krauss K, Fehm T et al. Symptomatic bone marrow involvement in breast cancer clinical presentation, treatment, and prognosis: a single institution review of 22 cases. Anticancer Res 2011; 31:4025-4030.
18. Salacz ME, Lankewicz MW, Weissmann DE. Management of thrombocytopenia in bone marrow failure: a review. J Palliat Med 2007; 10:236-244. (Pubitemid 46238970)