Thrombotic microangiopathy and disseminated intravascular coagulation associated with carcinocythemia in a patient with breast cancer

Journal of Clinical Oncology

Volumn 29, Issue 34, 2011, Pages

  Robier, Christoph ^a   Neubauer, Manfred ^a   Beham Schmid, Christine ^b   Sill, Heinz ^b  

^a KRANKENHAUS DER BARMHERZIGEN BRÜDER   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; BILIRUBIN; CYCLOPHOSPHAMIDE; CYTOKERATIN 19; D DIMER; EPIRUBICIN; FIBRINOGEN; FRESH FROZEN PLASMA; HEMOGLOBIN; LACTATE DEHYDROGENASE;

ADULT; ARTICLE; AUTOPSY; BLOOD SMEAR; BONE METASTASIS; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER PATIENT; CANCER REGRESSION; CARCINOCYTHEMIA; CARCINOMATOUS LYMPHANGIOSIS; CASE REPORT; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONCENTRATION (PARAMETERS); DISEASE ASSOCIATION; DISEASE COURSE; DISSEMINATED INTRAVASCULAR CLOTTING; DYSPNEA; EPITHELIAL TUMOR CELL; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE COUNT; FATALITY; FEMALE; FIBRIN CLOT; HEMATOLOGIC DISEASE; HEMOLYTIC ANEMIA; HOSPITAL ADMISSION; HUMAN; IMMUNOCYTOCHEMISTRY; INTRADUCTAL CARCINOMA; LABORATORY TEST; LEUKOCYTOSIS; LIVER METASTASIS; LUNG CAPILLARY; LUNG METASTASIS; LYMPHATIC SYSTEM DISEASE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; MULTIPLE CYCLE TREATMENT; MYELOPHTHISIC ANEMIA; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; RETICULOCYTE COUNT; SUBCUTANEOUS HEMORRHAGE; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT FAILURE; TUMOR CELL;

AGED; BREAST NEOPLASMS; DISSEMINATED INTRAVASCULAR COAGULATION; FEMALE; HUMANS; LEUKEMIA; NEOPLASM METASTASIS; THROMBOTIC MICROANGIOPATHIES;

EID: 83355174076     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2011.36.7433     Document Type: Article

References (20)

1. Levi M, Toh CH, Thachil J, et al: Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol 145:24-33, 2009
2. Jaffe EA, Nachman RL, Merskey C: Thrombotic thrombocytopenic purpura: Coagulation parameters in twelve patients. Blood 42:499-507, 1973
3. Contrino J, Hair G, Kreutzer DL, et al: In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease. Nat Med 2:209-215, 1996 (Pubitemid 26054985)
4. Loreto MF, De Martinis M, Corsi MP, et al: Coagulation and cancer: Implications for diagnosis and management. Pathol Oncol Res 6:301-312, 2000 (Pubitemid 32167627)
5. Colman RW, Rubin RN: Disseminated intravascular coagulation due to malignancy. Semin Oncol 17:172-186, 1990 (Pubitemid 20131808)
6. Gallivan MV, Lokich JJ: Carcinocythemia (carcinoma cell leukemia). Report of two cases with English literature review. Cancer 53:1100-1102, 1984 (Pubitemid 14196489)
7. Murgo AJ: Thrombotic microangiopathy in the cancer patient including those induced by chemotherapeutic agents. Semin Hematol 24:161-177, 1987
8. Oleksowicz L, Bhagwati N, DeLeon-Fernandez M: Deficient activity of von Willebrand's factor-cleaving protease in patients with disseminated malignancies. Cancer Res 59:2244-2250, 1999 (Pubitemid 29217692)
9. Mannucci PM, Karimi M, Mosalaei A, et al: Patients with localized and disseminated tumors have reduced but measurable levels of ADAMTS-13 (von Willebrand factor cleaving protease). Haematologica 88:454-458, 2003 (Pubitemid 36547132)
10. Ruggeri ZM, Ware J: The structure and function of von Willebrand factor. Thromb Haemost 67:594-599, 1992
11. Lesesne JB, Rothschild N, Erickson B, et al: Cancer-associated haemolytic-uremic syndrome: Analysis of 85 cases from a national registry. J Clin Oncol 7:781-789, 1989 (Pubitemid 19145601)
12. Raife TJ, Lager DJ: Chronic thrombotic microangiopathy associated with antineoplastic therapy with minimal hematologic effects. Mayo Clin Proc 77:323-328, 2002 (Pubitemid 34260739)
13. Chang JC, Naqvi T: Thrombotic thrombocytopenic purpura associated with bone marrow metastasis and secondary myelofibrosis in cancer. Oncologist 8:375-380, 2003 (Pubitemid 36929722)
14. Brain MC, Azzopardi JG, Baker LR, et al: Microangiopathic haemolytic anaemia and mucin-forming adenocarcinoma. Br J Haematol 18:183-193, 1970
15. Carey RW, Taft PD, Bennett JM, et al: Carcinocythemia (carcinoma cell leukemia). An acute leukemia-like picture due to metastatic carcinoma cells. Am J Med 60:273-278, 1976
16. Chang Y, Hsieh R, Chang M, et al: Breast cancer with an unusual leukemia-like presentation: Case report and literature review. Med Oncol 25:100-103, 2008
17. Pitini V, Arrigo C, Altavilla G: An acute-leukemia-like picture due to breast carcinoma cells. Lancet Oncol 7:524, 2006 (Pubitemid 43779177)
18. Brace W, Bain B, Walker M, et al: Teaching cases from the Royal Marsden Hospital: Case 9 - An elderly patient with unusual circulating cells. Leuk Lymphoma 18:529-530, 1995
19. Myerowitz RL, Edwards PA, Sartiano GP: Carcinocythemia (carcinoma cell leukemia) due to metastatic carcinoma of the breast: Report of a case. Cancer 40:3107-3111, 1977
20. Yam LT, Janckila AJ: Immunocytodiagnosis of carcinocythemia in disseminated breast cancer. Acta Cytol 31:68-72, 1987 (Pubitemid 17010983)