메뉴 건너뛰기




Volumn 29, Issue 6, 2012, Pages 539-546

Molecular and cytogenetic studies of 101 infertile men with microdeletions of y chromosome in 1, 306 infertile Korean men

Author keywords

Azoospermia factor (AZF); Chromosomal abnormality; Intracytoplasmic sperm injection (ICSI); Y chromosome microdeletion

Indexed keywords

ADULT; ARTICLE; AZOOSPERMIA; CHROMOSOME ANALYSIS; CHROMOSOME DELETION Y; CHROMOSOME STRUCTURE; CONTROLLED STUDY; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; GENETIC ASSOCIATION; GENETIC COUNSELING; GENETIC SCREENING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INCIDENCE; INTRACYTOPLASMIC SPERM INJECTION; KOREA; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; PREGNANCY OUTCOME; PREVALENCE; PRIORITY JOURNAL; PROGENY; RETROSPECTIVE STUDY; SPERM; SPERMATOGENESIS; SPERMATOZOON COUNT; TESTIS; TESTIS BIOPSY;

EID: 84864912776     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-012-9748-4     Document Type: Article
Times cited : (44)

References (50)
  • 2
    • 34248216100 scopus 로고    scopus 로고
    • Investigation and assisted reproduction in the treatment of male infertility
    • Pasqualotto FF. Investigation and assisted reproduction in the treatment of male infertility. Rev Bras Ginecol Obstet. 2007;29:103-12.
    • (2007) Rev Bras Ginecol Obstet , vol.29 , pp. 103-112
    • Pasqualotto, F.F.1
  • 3
    • 0027221554 scopus 로고
    • Recommendations of the ESHRE workshop on unexplained infertility
    • Crosignani PG, et al. Recommendations of the ESHRE workshop on unexplained infertility. Hum Reprod. 1993;8(6):977-80.
    • (1993) Hum Reprod , vol.8 , Issue.6 , pp. 977-980
    • Crosignani, P.G.1
  • 4
    • 0026726199 scopus 로고
    • Microdeletions in interval 6 of the y chromosome of males with idiopathic sterility point to disruption of AZF, a human spermatogenesis gene
    • Vogt P, et al. Microdeletions in interval 6 of the Y chromosome of males with idiopathic sterility point to disruption of AZF, a human spermatogenesis gene. Hum Genet. 1992;89(5):491-6.
    • (1992) Hum Genet , vol.89 , Issue.5 , pp. 491-496
    • Vogt, P.1
  • 5
    • 33947546526 scopus 로고    scopus 로고
    • Molecular and clinical characterization of y chromosome microdeletions in infertile men: A 10-year experience in Italy
    • Ferlin A, et al. Molecular and clinical characterization of Y chromosome microdeletions in infertile men: a 10-year experience in Italy. J Clin Endocrinol Metab. 2007;92:762-70
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 762-770
    • Ferlin, A.1
  • 6
    • 0031835155 scopus 로고    scopus 로고
    • Chromosome anomalies and y chromosome microdeletions as causal factors in male infertility
    • Chandley AC. Chromosome anomalies and Y chromosome microdeletions as causal factors in male infertility. Hum Reprod. 1998;13(1):45-50
    • (1998) Hum Reprod , vol.13 , Issue.1 , pp. 45-50
    • Chandley, A.C.1
  • 7
    • 0007272350 scopus 로고    scopus 로고
    • Human y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11
    • Vogt PH, et al. Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11. Hum Mol Genet. 1996;5 (7):933-43
    • (1996) Hum Mol Genet , vol.5 , Issue.7 , pp. 933-943
    • Vogt, P.H.1
  • 9
    • 0035012270 scopus 로고    scopus 로고
    • Y chromosome microdeletions and alterations of spermatogenesis
    • Foresta C, Moro E, Ferlin A. Y chromosome microdeletions and alterations of spermatogenesis. Endocr Rev. 2001;22:226-39
    • (2001) Endocr Rev , vol.22 , pp. 226-239
    • Foresta, C.1    Moro, E.2    Ferlin, A.3
  • 10
    • 0029088061 scopus 로고
    • Diverse spermatogenic defects in human caused by y chromosome deletions encompassing a novel RNA-binding protein gene
    • Reijo R, et al. Diverse spermatogenic defects in human caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nature Gen. 1995;10:383-93
    • (1995) Nature Gen , vol.10 , pp. 383-393
    • Reijo, R.1
  • 11
    • 70349392472 scopus 로고    scopus 로고
    • Genetic anomalies in patients with severe oligozoospermia and azoospermia in eastern Turkey: A prospective study
    • Ceylan GG, Ceylan C, Elyas H. Genetic anomalies in patients with severe oligozoospermia and azoospermia in eastern Turkey: a prospective study. Genet Mol Res. 2009;8(3):915-22
    • (2009) Genet Mol Res , vol.8 , Issue.3 , pp. 915-922
    • Ceylan, G.G.1    Ceylan, C.2    Elyas, H.3
  • 12
    • 49749142579 scopus 로고    scopus 로고
    • A study of y chromosome microdeletions in infertile Indian males
    • Athalye AS, et al. A study of Y chromosome microdeletions in infertile Indian males. Int J Hum Genet. 2004;4:179-85
    • (2004) Int J Hum Genet , vol.4 , pp. 179-185
    • Athalye, A.S.1
  • 13
    • 84867545171 scopus 로고    scopus 로고
    • Yq microdeletions-azoospermia factor candidate genes and spermatogenic arrest
    • Dada R, Gupta NP, Kucheria K. Yq microdeletions-azoospermia factor candidate genes and spermatogenic arrest. J Biomol Tech. 2004;15(3):176-83
    • (2004) J Biomol Tech , vol.15 , Issue.3 , pp. 176-183
    • Dada, R.1    Gupta, N.P.2    Kucheria, K.3
  • 14
    • 0141465110 scopus 로고    scopus 로고
    • Screening for microdeletions in human y chromosome-AZF candidate genes and male infertility
    • Raicu F, et al. Screening for microdeletions in human Y chromosome-AZF candidate genes and male infertility. J Cell Mol Med. 2003;7(1):43-8.
    • (2003) J Cell Mol Med , vol.7 , Issue.1 , pp. 43-48
    • Raicu, F.1
  • 15
    • 0031196792 scopus 로고    scopus 로고
    • Combined cytogenetic and y chromosome microdeletion screening in males undergoing intracytoplasmic sperm injection
    • van der Ven K, et al. Combined cytogenetic and Y chromosome microdeletion screening in males undergoing intracytoplasmic sperm injection. Mol Hum Reprod. 1997;3:699-70.
    • (1997) Mol Hum Reprod , vol.3 , pp. 699-770
    • Van Der Ven, K.1
  • 16
    • 0031889383 scopus 로고    scopus 로고
    • High frequency of well-defined Y-chromosome deletions in idiopathic Sertoli cell-only syndrome
    • Foresta C, et al. High frequency of well-defined Y-chromosome deletions in idiopathic Sertoli cell-only syndrome. Hum Reprod. 1998;13:302-7.
    • (1998) Hum Reprod , vol.13 , pp. 302-307
    • Foresta, C.1
  • 17
    • 0028114292 scopus 로고
    • PCR analysis of the y chromosome long arm in azoospermic patients: Evidence for a second locus required for spermatogenesis
    • Kobayashi K, et al. PCR analysis of the Y chromosome long arm in azoospermic patients: Evidence for a second locus required for spermatogenesis. Hum Mol Genet. 1994;3:1965-7.
    • (1994) Hum Mol Genet , vol.3 , pp. 1965-1967
    • Kobayashi, K.1
  • 18
    • 0029798989 scopus 로고    scopus 로고
    • The y chromosome region essential for spermatogenesis
    • Nakahori Y, et al. The Y chromosome region essential for spermatogenesis. Horm Res. 1996;46 Suppl 1:20-3.
    • (1996) Horm Res , vol.46 , Issue.SUPPL. 1 , pp. 20-23
    • Nakahori, Y.1
  • 19
    • 0035069879 scopus 로고    scopus 로고
    • Screening for deletions in interval D16-22 of the y chromosome in azoospermic and oligozoospermic Japanese men
    • Kato H, et al. Screening for deletions in interval D16-22 of the Y chromosome in azoospermic and oligozoospermic Japanese men. J Hum Genet. 2001;46:110-4.
    • (2001) J Hum Genet , vol.46 , pp. 110-114
    • Kato, H.1
  • 20
    • 0036272336 scopus 로고    scopus 로고
    • Microdeletions of a Y-specific marker, Yfm1, and implications for a role in spermatogenesis
    • Ewis AA, et al. Microdeletions of a Y-specific marker, Yfm1, and implications for a role in spermatogenesis. J Hum Genet. 2002;47:257-61
    • (2002) J Hum Genet , vol.47 , pp. 257-261
    • Ewis, A.A.1
  • 21
    • 0036274330 scopus 로고    scopus 로고
    • Molecular analysis of the y chromosome AZFc region in Japanese infertile males with spermatogenic defects
    • Sawai H, et al. Molecular analysis of the Y chromosome AZFc region in Japanese infertile males with spermatogenic defects. J Reprod Immunol. 2002;53:37-44
    • (2002) J Reprod Immunol , vol.53 , pp. 37-44
    • Sawai, H.1
  • 22
    • 2342460435 scopus 로고    scopus 로고
    • Embryo outcome in Y-chromosome microdeleted infertile males after ICSI
    • Kihaile PE, et al. Embryo outcome in Y-chromosome microdeleted infertile males after ICSI. Mol Reprod Dev. 2004;68:176-81
    • (2004) Mol Reprod Dev , vol.68 , pp. 176-181
    • Kihaile, P.E.1
  • 23
    • 0036159094 scopus 로고    scopus 로고
    • Relationship between microdeletion on y chromosome and patients with idiopathic azoospermia and severe oligozoospermia in the Chinese
    • Fu J, Li L, Lu G. Relationship between microdeletion on Y chromosome and patients with idiopathic azoospermia and severe oligozoospermia in the Chinese. Chin Med J. 2002;115:72-5.
    • (2002) Chin Med J , vol.115 , pp. 72-75
    • Fu, J.1    Li, L.2    Lu, G.3
  • 24
    • 25844469957 scopus 로고    scopus 로고
    • Screening for y chromosome microdeletions in idiopathic and nonidiopathic infertile men with varicocele and cryptorchidism
    • Song NH, et al. Screening for Y chromosome microdeletions in idiopathic and nonidiopathic infertile men with varicocele and cryptorchidism. Chin Med J. 2005;118:1462-7.
    • (2005) Chin Med J , vol.118 , pp. 1462-1467
    • Song, N.H.1
  • 25
    • 0033663681 scopus 로고    scopus 로고
    • Y-chromosome microdeletion and its effect on reproductive decisions in Taiwanese patients presenting with nonobstructive azoospermia
    • Lin YM, et al. Y-chromosome microdeletion and its effect on reproductive decisions in Taiwanese patients presenting with nonobstructive azoospermia. Urology. 2000;56:1041-6.
    • (2000) Urology , vol.56 , pp. 1041-1046
    • Lin, Y.M.1
  • 26
    • 0036247892 scopus 로고    scopus 로고
    • Gene-based screening for y chromosome deletions in Taiwanese men presenting with spermatogenic failure
    • Lin YM, et al. Gene-based screening for Y chromosome deletions in Taiwanese men presenting with spermatogenic failure. Fertil Steril. 2002;77:897-90.
    • (2002) Fertil Steril , vol.77 , pp. 897-990
    • Lin, Y.M.1
  • 27
    • 61849097128 scopus 로고    scopus 로고
    • Chromosomal anomalies and Y-microdeletions among Chinese subfertile men in Hong Kong
    • Ng PP, et al. Chromosomal anomalies and Y-microdeletions among Chinese subfertile men in Hong Kong. Hong Kong Med J. 2009;15(1):31-8.
    • (2009) Hong Kong Med J , vol.15 , Issue.1 , pp. 31-38
    • Ng, P.P.1
  • 28
    • 0037342817 scopus 로고    scopus 로고
    • Molecular screening for Yq microdeletion in men with idiopathic oligozoospermia and azoospermia
    • Dada R, Gupta NP, Kucheria K. Molecular screening for Yq microdeletion in men with idiopathic oligozoospermia and azoospermia. Journal of Bioscience. 2003;28:163-8.
    • (2003) Journal of Bioscience , vol.28 , pp. 163-168
    • Dada, R.1    Gupta, N.P.2    Kucheria, K.3
  • 29
    • 39449097537 scopus 로고    scopus 로고
    • Clinical and laboratory evaluation of idiopathic male infertility in a secondary referral center in India
    • Abid S, et al. Clinical and laboratory evaluation of idiopathic male infertility in a secondary referral center in India. J Clin Lab Anal. 2008;22:29-38
    • (2008) J Clin Lab Anal , vol.22 , pp. 29-38
    • Abid, S.1
  • 30
    • 84355166682 scopus 로고    scopus 로고
    • Clinical diagnostic testing for the cytogenetic and molecular causes of male infertility: The Mayo Clinic experience
    • Hofherr SE, et al. Clinical diagnostic testing for the cytogenetic and molecular causes of male infertility: the Mayo Clinic experience. J Assist Reprod Genet. 2011;28:1091-8.
    • (2011) J Assist Reprod Genet , vol.28 , pp. 1091-1098
    • Hofherr, S.E.1
  • 31
    • 65249101691 scopus 로고
    • Chromosomal aberrations as a cause of male subfertility
    • Lange R, Engel W. Chromosomal aberrations as a cause of male subfertility. J Fertil Reprod. 1991;9:41-4.
    • (1991) J Fertil Reprod , vol.9 , pp. 41-44
    • Lange, R.1    Engel, W.2
  • 32
    • 0036161218 scopus 로고    scopus 로고
    • Genetic risk factors in infertile men with severe oligozoospermia and azoospermia
    • Dohle GR, et al. Genetic risk factors in infertile men with severe oligozoospermia and azoospermia. Hum Reprod. 2002;17(1):13-6.
    • (2002) Hum Reprod , vol.17 , Issue.1 , pp. 13-16
    • Dohle, G.R.1
  • 33
    • 84864948819 scopus 로고    scopus 로고
    • WHO. World Health Organization Laboratory Manual for the Examination of Human Semen and Sperm and Sperm-Cervical Mucus Interaction. UK: Cambridge University Press
    • WHO. World Health Organization Laboratory Manual for the Examination of Human Semen and Sperm and Sperm-Cervical Mucus Interaction. UK: Cambridge University Press; 1999.
    • (1999)
  • 34
    • 65249132992 scopus 로고    scopus 로고
    • A genetic survey of 1935 Turkish men with severe male factor infertility
    • Kumtepe Y, et al. A genetic survey of 1935 Turkish men with severe male factor infertility. Reprod Biomed Online. 2009;18 (4):465-74
    • (2009) Reprod Biomed Online , vol.18 , Issue.4 , pp. 465-474
    • Kumtepe, Y.1
  • 35
    • 33845987078 scopus 로고    scopus 로고
    • Frequency of y chromosome microdeletions and chromosomal abnormalities in infertile Thai men with oligozoospermia and azoospermia
    • Vutyavanich T, et al. Frequency of Y chromosome microdeletions and chromosomal abnormalities in infertile Thai men with oligozoospermia and azoospermia. Asian J Androl. 2007;9:68-75
    • (2007) Asian J Androl , vol.9 , pp. 68-75
    • Vutyavanich, T.1
  • 36
    • 0021354634 scopus 로고
    • Chromosome studies in 496 infertile males with a sperm count below 10 million per ml
    • Retief A, Van Zyl J, Menkveld M. Chromosome studies in 496 infertile males with a sperm count below 10 million per ml. Hum Genet. 1984;66:162-4.
    • (1984) Hum Genet , vol.66 , pp. 162-164
    • Retief, A.1    Van Zyl, J.2    Menkveld, M.3
  • 37
    • 0026890096 scopus 로고
    • Chromosomal survey of 1001 subfertile males: Incidence and clinical features of males with chromosomal anomalies
    • Matsuda T, et al. Chromosomal survey of 1001 subfertile males: incidence and clinical features of males with chromosomal anomalies. Acta Urol Jpn. 1992;38:803-9.
    • (1992) Acta Urol Jpn , vol.38 , pp. 803-809
    • Matsuda, T.1
  • 38
    • 5044221832 scopus 로고    scopus 로고
    • Genetic aspects of human male infertility: The frequency of chromosomal abnormalities and y chromosome microdeletions in severe male factor infertility
    • Vicdan et al. Genetic aspects of human male infertility: the frequency of chromosomal abnormalities and Y chromosome microdeletions in severe male factor infertility. Eur J Obstet Gynecol Reprod Biol. 2004;117:289-92
    • (2004) Eur J Obstet Gynecol Reprod Biol , vol.117 , pp. 289-292
    • Vicdan1
  • 39
    • 75749150197 scopus 로고    scopus 로고
    • Clinical data and parenthood of 63 infertile and Y-microdeleted men
    • Patrat C, et al. Clinical data and parenthood of 63 infertile and Y-microdeleted men. Fertil Steril. 2010;93:822-32
    • (2010) Fertil Steril , vol.93 , pp. 822-832
    • Patrat, C.1
  • 40
    • 0037136948 scopus 로고    scopus 로고
    • Effects of transmission of y chromosome AZFc deletions
    • Patsalis P, et al. Effects of transmission of Y chromosome AZFc deletions. Lancet. 2002;360:1222-4.
    • (2002) Lancet , vol.360 , pp. 1222-1224
    • Patsalis, P.1
  • 41
    • 33344458754 scopus 로고    scopus 로고
    • Natural history of prenatally diagnosed 46, X, isodicentric y
    • Willis M, et al. Natural history of prenatally diagnosed 46, X, isodicentric Y. Prenat Diagn. 2006;26:134-7.
    • (2006) Prenat Diagn , vol.26 , pp. 134-137
    • Willis, M.1
  • 42
    • 38949191627 scopus 로고    scopus 로고
    • High incidence of Y-chromosome microdeletions in gonadal tissues from patients with 45, X/46, XY gonadal dysgenesis
    • Alvarez-Nava F, et al. High incidence of Y-chromosome microdeletions in gonadal tissues from patients with 45, X/46, XY gonadal dysgenesis. Fertil Steril. 2008;89:458-60
    • (2008) Fertil Steril , vol.89 , pp. 458-460
    • Alvarez-Nava, F.1
  • 43
    • 0033803789 scopus 로고    scopus 로고
    • Prognostic value of y deletion analysis: What is the clinical prognostic value of y chromosome microdeletion analysis?
    • Krausz C, Quintana-Murci L, McElreavey K. Prognostic value of Y deletion analysis: what is the clinical prognostic value of Y chromosome microdeletion analysis? Hum Reprod. 2000;15:1431-4.
    • (2000) Hum Reprod , vol.15 , pp. 1431-1434
    • Krausz, C.1    Quintana-Murci, L.2    McElreavey, K.3
  • 44
    • 0034971870 scopus 로고    scopus 로고
    • Double-blind y chromosome microdeletion analysis in men with known sperm parameters and reproductive hormone profiles: Microdeletions are specific for spermatogenic failure
    • Krausz C, et al. Double-blind Y chromosome microdeletion analysis in men with known sperm parameters and reproductive hormone profiles: microdeletions are specific for spermatogenic failure. J Clin Endocrinol Metab. 2001;86:2638-42
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2638-2642
    • Krausz, C.1
  • 45
    • 0035130979 scopus 로고    scopus 로고
    • Decreased fertilization rate and embryo quality after ICSI in oligozoospermic men with microdeletions in the azoospermia factor c region of the y chromosome
    • van Golde RJT, et al. Decreased fertilization rate and embryo quality after ICSI in oligozoospermic men with microdeletions in the azoospermia factor c region of the Y chromosome. Hum Reprod. 2001;16:289-92
    • (2001) Hum Reprod , vol.16 , pp. 289-292
    • Van Golde, R.J.T.1
  • 46
    • 0036852977 scopus 로고    scopus 로고
    • Clinical characterization of 42 oligospermic or azoospermic men with microdeletion of the AZFc region of the y chromosome, and of 18 children conceived via ICSI
    • Oates RD, et al. Clinical characterization of 42 oligospermic or azoospermic men with microdeletion of the AZFc region of the Y chromosome, and of 18 children conceived via ICSI. Hum Reprod. 2002;17:2813-24
    • (2002) Hum Reprod , vol.17 , pp. 2813-2824
    • Oates, R.D.1
  • 47
    • 84872214636 scopus 로고    scopus 로고
    • Effects of y Chromosome Microdeletion on the Outcome of in vitro Fertilization
    • Choi NM, et al. Effects of Y Chromosome Microdeletion on the Outcome of in vitro Fertilization. Kor J Fertil Steril. 2007;34(1):41-8.
    • (2007) Kor J Fertil Steril , vol.34 , Issue.1 , pp. 41-48
    • Choi, N.M.1
  • 48
    • 21644483723 scopus 로고    scopus 로고
    • The choice and outcome of the fertility treatment of 38 couples in whom the male partner has a Yq microdeletion
    • Stouffs K, et al. The choice and outcome of the fertility treatment of 38 couples in whom the male partner has a Yq microdeletion. Hum Reprod. 2005;20:1887-96
    • (2005) Hum Reprod , vol.20 , pp. 1887-1896
    • Stouffs, K.1
  • 49
    • 1242306489 scopus 로고    scopus 로고
    • AZF microdeletions of the y chromosome and in vitro fertilization outcome
    • Choi JM, et al. AZF microdeletions of the Y chromosome and in vitro fertilization outcome. Fertil Steril. 2004;81:337-41
    • (2004) Fertil Steril , vol.81 , pp. 337-341
    • Choi, J.M.1
  • 50
    • 33646105631 scopus 로고    scopus 로고
    • Intracytoplasmic sperm injection may lead to vertical transmission expansion and de novo occurrence of Y-chromosome microdeletions in male fetuses
    • Lee SH, et al. Intracytoplasmic sperm injection may lead to vertical transmission, expansion, and de novo occurrence of Y-chromosome microdeletions in male fetuses. Fertil Steril. 2006;85(5):1512-5.
    • (2006) Fertil Steril , vol.85 , Issue.5 , pp. 1512-1515
    • Lee, S.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.