Frequency of Y chromosome microdeletions and chromosomal abnormalities in infertile Thai men with oligozoospermia and azoospermia

Asian Journal of Andrology

Volumn 9, Issue 1, 2007, Pages 68-75

  Vutyavanich, Teraporn ^a   Piromlertamorn, Waraporn ^a   Sirirungsi, Wasna ^b   Sirisukkasem, Supachai ^a  

^a THAMMASAT UNIVERSITY   (Thailand)

^b CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

Azoospermia; Azoospermia factor; Male infertility; Oligozoo spermia; Y chromosome microdeletions

Indexed keywords

AZOOSPERMIA FACTOR; FOLLITROPIN; GENE PRODUCT; LUTEINIZING HORMONE; PROLACTIN; TESTOSTERONE; UNCLASSIFIED DRUG;

ADULT; ANAMNESIS; ARTICLE; AZOOSPERMIA; CHEMOLUMINESCENCE; CHROMOSOME ABERRATION; CHROMOSOME BANDING PATTERN; CHROMOSOME DELETION; CLINICAL EXAMINATION; CONTROLLED STUDY; CRYPTORCHISM; HORMONE DETERMINATION; HUMAN; HUMAN CELL; IMMUNOASSAY; KARYOTYPE; KARYOTYPING; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OLIGOSPERMIA; ORCHITIS; PATHOGENESIS; POLYMERASE CHAIN REACTION; SEMEN ANALYSIS; THAILAND; UROGENITAL SYSTEM EXAMINATION; Y CHROMOSOME;

AZOOSPERMIA; BASE SEQUENCE; CHROMOSOME MAPPING; DNA PRIMERS; FOLLICLE STIMULATING HORMONE; HUMANS; INFERTILITY, MALE; KARYOTYPING; LUTEINIZING HORMONE; MALE; OLIGOSPERMIA; PROLACTIN; SEQUENCE DELETION; SEX CHROMOSOME ABERRATIONS; XYY KARYOTYPE; Y CHROMOSOME;

EID: 33845987078     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1111/j.1745-7262.2007.00239.x     Document Type: Article

References (20)

1. Fernando L, Gromoll J, Weerasooriya TR, Nieschlag E, Simoni M. Y-chromosomal microdeletions and partial deletions of the Azoospermia Factor c (AZFc) region in normozoospermic, severe oligozoospermic and azoospermic men in Sri Lanka. Asian J Androl 2006; 8: 39-44.
2. Vogt PH. Molecular genetics of human male infertility: From genes to new therapeutic perspectives. Curr Pharm Des 2004; 10: 471-500.
3. van Assche E, Bonduelle M, Tournaye H, Joris H, Verheyen G, Devroey P, et al. Cytogenetics of infertile men. Hum Reprod 1996; 11: 1-24.
4. Vicdan A, Vicdan K, Gunalp S, Kence A, Akarsu C, Isik AZ, et al. Genetic aspects of human male infertility: The frequency of chromosomal abnormalities and Y chromosome microdeletions in severe male factor infertility. Eur J Obstet Gynecol Reprod Biol 2004; 117: 49-54.
5. Sargin CF, Berker-Karauzum S, Manguoglu E, Erdogru T, Karaveli S, Gulkesen KH, et al. AZF microdeletions on the Y chromosome of infertile men from Turkey. Ann Genet 2004; 47: 61-8.
6. World Health Organization. Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. 4th ed. Cambridge: Cambridge University Press; 1999.
7. Lin YM, Lin YH, Teng YN, Hsu CC, Shinn-Nan LJ, Kuo PL. Gene-based screening for Y chromosome deletions in Taiwanese men presenting with spermatogenic failure. Fertil Steril 2002; 77: 897-903.
8. Tse JY, Yeung WS, Ng EH, Cheng LN, Zhu HB, Teng XM, et al. A comparative study of Y chromosome microdeletions in infertile males from two Chinese populations. J Assist Reprod Genet 2002; 19: 376-83.
9. Gottlieb B, Lombroso R, Beitel LK, Trifiro MA. Molecular pathology of the androgen receptor in male (in)fertility. Reprod Biomed Online 2005; 10: 42-8.
10. Foresta C, Garolla A, Bartoloni L, Bettella A, Ferlin A. Genetic abnormalities among severely oligospermic men who are candidates for intracytoplasmic sperm injection. J Clin Endocrinol Metab 2005; 90: 152-6.
11. Tomasi PA, Oates R, Brown L, Delitala G, Page DC. The pituitary-testicular axis in Klinefelter's syndrome and in oligoazoospermic patients with and without deletions of the Y chromosome long arm. Clin Endocrinol (Oxf) 2003; 59: 214-22.
12. Fagerli J, Schneck FX, Lee PA, Bellinger MF, Witchel SF. Absence of microdeletions in the Y chromosome in patients with a history of cryptorchidism and azoospermia or oligospermia. Fertil Steril 1999; 71: 697-700.
13. Simoni M, Gromoll J, DworniczakB, Rolf C, Abshagen K, Kamischke A, et al. Screening for deletions of the Y chromosome involving the DAZ (Deleted in AZoospermia) gene in azoospermia and severe oligozoospermia. Fertil Steril 1997; 67: 542-7.
14. Chen S, Lien Y, Ko T, Ho H, Yang Y, Chang H. Genetic screening of karyotypes and azoospermic factors for infertile men who are candidates for ICSI. Arch Androl 2003; 49: 423-7.
15. Aho M, Harkonen K, Suikkari A, Juvonen V, Anttila L, Lahdetie J. Y-chromosomal microdeletions among infertile Finnish men. Acta Obstet Gynecol Scand 2001; 80: 652-6.
16. Kim SW, Kim KD, Paick JS. Microdeletions within the azoospermia factor subregions of the Y chromosome in patients with idiopathic azoospermia. Fertil Steril 1999; 72: 349-53.
17. Nakashima M, Koh E, Namiki M, Yoshida A. Multiplex sequence-tagged site PCR for efficient screening of microdeletions in Y chromosome in infertile males with azoospermia or severe oligozoospermia. Arch Androl 2002; 48: 351-8.
18. Martinez MC, Bernabe MJ, Gomez E, Ballesteros A, Landeras J, Glover G, et al. Screening for AZF deletion in a large series of severely impaired spermatogenesis patients. J Androl 2000; 21: 651-5.
19. Ioulianos A, Sismani C, Fourouclas N, Patroclou T, Sergiou C, Patsalis PC. A nation-based population screening for azoospermia factor deletions in Greek-Cypriot patients with severe spermatogenic failure and normal fertile controls, using a specific study and experimental design. Int JAndrol 2002; 25: 153-8.
20. Stouffs K, Lissens W, Verheyen G, van Landuyt L, Goossens A, Tournaye H, et al. Expression pattern of the Y-linked PRY gene suggests a function in apoptosis but not in spermatogenesis. Mol Hum Reprod 2004; 10: 15-21.