Cathepsin G inhibitor prevents ultraviolet B-induced photoaging in hairless mice via inhibition of fibronectin fragmentation

Dermatology

Volumn 224, Issue 4, 2012, Pages 352-360

  Son, E D ^a,b   Shim, J H ^a   Choi, H ^a   Kim, H ^a   Lim, K M ^a   Chung, J H ^c   Byun, S Y ^b   Lee, T R ^a  

^a AmorePacific Corporation   (South Korea)

^b Ajou University   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

Cathepsin G; Fibronectin; Matrix metalloproteinase; Photoaging; Skin

Indexed keywords

3,4 DICHLOROISOCOUMARIN; [2 [3 [[(1 BENZOYL 4 PIPERIDINYL)METHYLAMINO]CARBONYL] 2 NAPHTHALENYL] 1 (1 NAPHTHALENYL) 2 OXOETHYL]PHOSPHONIC ACID; BENZYLOXYCARBONYLGLYCYLLEUCYLPHENYLALANYL CHLOROMETHYL KETONE; CATHEPSIN G INHIBITOR; CHYMOSTATIN; COLLAGEN; FIBRONECTIN; GELATINASE A; GELATINASE B; N ACETYLEGLIN C; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME REGULATION; EXTRACELLULAR MATRIX; FEMALE; HAIRLESS MOUSE; MOUSE; NONHUMAN; PHOTOAGING; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN DEGRADATION; ULTRAVIOLET B RADIATION;

ANIMALS; BLOTTING, WESTERN; CATHEPSIN G; COLLAGEN; ELASTIN; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBRONECTINS; MATRIX METALLOPROTEINASE 1; MICE; MICE, HAIRLESS; MODELS, ANIMAL; NAPHTHALENES; ORGANOPHOSPHORUS COMPOUNDS; PIPERIDINES; REAL-TIME POLYMERASE CHAIN REACTION; SKIN; SKIN AGING; TISSUE INHIBITOR OF METALLOPROTEINASE-1; ULTRAVIOLET RAYS;

EID: 84864885385     PISSN: 10188665     EISSN: 14219832     Source Type: Journal    
DOI: 10.1159/000339337     Document Type: Article

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