Poly(ADD-ribose) Polymerse Localizes to the centrosomes and chromosomes

Biochemical and Biophysical Research Communications

Volumn 278, Issue 2, 2000, Pages 385-389

  Kanai, Masayuki ^a   Uchida, Masahiro ^a   Hanai, Shuji ^a   Uematsu, Naoya ^a   Uchida, Kazuhiko ^a   Miwa, Masanao ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Aneuploidy; Cell division; Centrosome; Chromosomal instability; Mitosis; PARP

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANEUPLOIDY; ARTICLE; CELL DIVISION; CENTROSOME; CHROMOSOMAL LOCALIZATION; CHROMOSOME SEGREGATION; DNA REPAIR; DNA STRAND BREAKAGE; GENETIC STABILITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MITOSIS; PRIORITY JOURNAL; CELL CULTURE; CELL LINE; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN CHROMOSOME; METABOLISM;

CELL LINE; CENTROSOME; CHROMOSOMES, HUMAN; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MITOSIS; POLY(ADP-RIBOSE) POLYMERASES; TUMOR CELLS, CULTURED;

EID: 0034687531     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.3801     Document Type: Article

References (30)

1. Overproduction of the poly(ADP-ribose) polymerase DNAbinding domain blocks alkylation-induced DNA repair synthesis in mammalian cells
2. Overexpression of poly(ADP-ribose) polymerase promotes cell cycle arrest and inhibits neutrophilic differentiation of NB4 acute promyelocytic leukemia cells
3. Function of poly(ADP-ribose) polymerase in response to DNA damage: Gene-disruption study in mice
4. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapyinduced apoptosis
5. Cleavage of poly(ADP)-ribose) polymerase by a proteinase with properties like ICE
6. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
7. PARP cleavage in the apoptotic pathway in S2 cells from Drosophila melanogaster
8. Poly(ADP-ribose) polymerase-1: What have we learned from the deficient mouse model?
9. Poly(ADP-ribose): Historical perspective
10. Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
11. PARP is important for genomic stability but dispensable in apoptosis
12. Chromosomal aberrations in PARP(-/-) mice: Genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA
13. Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability
14. Altered centrosome structure is associated with abnormal mitoses in human breast tumors
15. Formation of the tetraploid intermediste is associated with the development of cells with more than four centrioles in the lastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer
16. Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells
17. Abnormal centrosome amplification in the absence of p53
18. Multiple centrosomal microtubule organising centres and increased microtubule stability are early features of VP-16-induced apoptosis in CCRF-CEM cells
19. The coordination of centrosome reproduction with nuclear events of the cell cycle in the sea urchin zygote
20. Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome
21. Pericentrin, a highly conserved centrosome protein involved in microtubule organization
22. Microtubule organizing centers
23. Anaphase onset and dephosphorylation of mitotic phosphoproteins occur concomitantly
24. Centrosomes and cancer
25. Isolation of centrosomes from cultured animal cells
26. BRCA1 is associated with the centrosome during mitosis
27. Expression of human poly(ADP-ribose) polymerase with DNA-dependent enzymatic activity in Escherichia coli
28. Poly(ADP-ribose) polymerase at active centromeres and neocentromeres at metaphase
29. Cell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomes
30. The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase