Promoting atherosclerosis in type 1 diabetes through the selective activation of arachidonic acid and PGE2 production

Circulation Research

Volumn 111, Issue 4, 2012, Pages 394-396

  Watkins, Steven M ^a   Hotamisligil, Gökhan S ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; PROSTAGLANDIN E2;

ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CAUSAL ATTRIBUTION; HUMAN; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; MACROPHAGE; MONOCYTE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM;

EID: 84864869669     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.273508     Document Type: Article

References (6)

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2. Ellis JM, Mentock SM, Depetrillo MA, Koves TR, Sen S, Watkins SM, et al. Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs fatty acid oxidation and induces cardiac hypertrophy. Mol Cell Biol. 2011;31: 1252-1262.
3. Ellis JM, Li LO, Wu P-C, Koves TR, Ilkayeva O, Stevens RD, et al. Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. Cell Metab. 2010;12:53-64.
4. Li LO, Ellis JM, Paich HA, Wang S, Gong N, Altshuller G, et al. Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. J Biol Chem. 2009;284:27816-27826.
5. Gregor MF, Hotamisligil GS. Inflammatory mechanisms in obesity. Annu Rev Immunol. 2011;29:415-445.
6. Lobo S, Wiczer BM, Bernlohr DA. Functional analysis of long-chain acyl-CoA synthetase 1 in 3T3-L1 adipocytes. J Biol Chem. 2009;284: 18347-18356.