-
1
-
-
34249715284
-
Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with a trial fibrillation
-
Hylek EM, Evans-Molina C, Shea C, Henault LE, Regan S. Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with a trial fibrillation. Circulation 115(21), 2689-2696 (2007).
-
(2007)
Circulation
, vol.115
, Issue.21
, pp. 2689-2696
-
-
Hylek, E.M.1
Evans-Molina, C.2
Shea, C.3
Henault, L.E.4
Regan, S.5
-
2
-
-
0042387879
-
Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation
-
Hylek EM, Go AS, Chang Y et al. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N. Engl. J. Med. 349(11), 1019-1026 (2003).
-
(2003)
N. Engl. J. Med.
, vol.349
, Issue.11
, pp. 1019-1026
-
-
Hylek, E.M.1
Go, A.S.2
Chang, Y.3
-
3
-
-
59649117935
-
The largest prospective warfarin-treated cohort supports genetic forecasting
-
Wadelius M, Chen LY, Lindh JD et al. The largest prospective warfarin-treated cohort supports genetic forecasting. Blood 113(4), 784-792 (2009).
-
(2009)
Blood
, vol.113
, Issue.4
, pp. 784-792
-
-
Wadelius, M.1
Chen, L.Y.2
Lindh, J.D.3
-
4
-
-
81855169543
-
Emergency hospitalizations for adverse drug events in older Americans
-
Budnitz DS, Lovegrove MC, Shehab N, Richards CL. Emergency hospitalizations for adverse drug events in older Americans. N. Engl. J. Med. 365(21), 2002-2012 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, Issue.21
, pp. 2002-2012
-
-
Budnitz, D.S.1
Lovegrove, M.C.2
Shehab, N.3
Richards, C.L.4
-
5
-
-
45949103309
-
Pharmacology and management of the vitamin K antagonists: AMERICAN College of Chest Physicians evidence-based clinical practice guidelines
-
(8th Edition)
-
Ansell J, Hirsh J, Hylek E et al. Pharmacology and management of the vitamin K antagonists: AMERICAN College of Chest Physicians evidence-based clinical practice guidelines (8th Edition). Chest 133(Suppl. 6), S160-S198 (2008).
-
(2008)
Chest
, vol.133
, Issue.SUPPL. 6
-
-
Ansell, J.1
Hirsh, J.2
Hylek, E.3
-
6
-
-
0037382537
-
American heart association/american college of cardiology foundation guide to warfarin therapy
-
Hirsh J, Fuster V, Ansell J, Halperin JL. American Heart Association/American College of Cardiology Foundation guide to warfarin therapy. Circulation 107(12), 1692-1711 (2003).
-
(2003)
Circulation
, vol.107
, Issue.12
, pp. 1692-1711
-
-
Hirsh, J.1
Fuster, V.2
Ansell, J.3
Halperin, J.L.4
-
7
-
-
60849097257
-
Estimation of the warfarin dose with clinical and pharmacogenetic data
-
Klein TE, Altman RB, Eriksson N et al. Estimation of the warfarin dose with clinical and pharmacogenetic data. N. Engl. J. Med. 360(8), 753-764 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, Issue.8
, pp. 753-764
-
-
Klein, T.E.1
Altman, R.B.2
Eriksson, N.3
-
8
-
-
0036785249
-
Patient-specific factors predictive of warfarin dosage requirements
-
Absher RK, Moore ME, Parker MH. Patient-specific factors predictive of warfarin dosage requirements. Ann. Pharmacother. 36(10), 1512-1517 (2002).
-
(2002)
Ann. Pharmacother.
, vol.36
, Issue.10
, pp. 1512-1517
-
-
Absher, R.K.1
Moore, M.E.2
Parker, M.H.3
-
9
-
-
77958511313
-
Warfarin dosing in patients with impaired kidney function
-
Limdi NA, Limdi MA, Cavallari L et al. Warfarin dosing in patients with impaired kidney function. Am. J. Kidney Dis. 56(5), 823-831 (2010).
-
(2010)
Am. J. Kidney Dis.
, vol.56
, Issue.5
, pp. 823-831
-
-
Limdi, N.A.1
Limdi, M.A.2
Cavallari, L.3
-
10
-
-
62349134303
-
Validation of VKORC1 and CYP2C9 genotypes on interindividual warfarin maintenance dose: A prospective study in Chinese patients
-
Huang SW, Chen HS, Wang XQ et al. Validation of VKORC1 and CYP2C9 genotypes on interindividual warfarin maintenance dose: A prospective study in Chinese patients. Pharmacogenet. Genomics 19(3), 226-234 (2009).
-
(2009)
Pharmacogenet. Genomics
, vol.19
, Issue.3
, pp. 226-234
-
-
Huang, S.W.1
Chen, H.S.2
Wang, X.Q.3
-
11
-
-
47949086046
-
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
-
Gage BF, Eby C, Johnson JA et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin. Pharmacol. Ther. 84(3), 326-331 (2008).
-
(2008)
Clin. Pharmacol. Ther.
, vol.84
, Issue.3
, pp. 326-331
-
-
Gage, B.F.1
Eby, C.2
Johnson, J.A.3
-
12
-
-
36549030324
-
Randomized trial of genotype-guided versus standard warfarin dosing in patients initiating oral anticoagulation
-
Anderson JL, Horne BD, Stevens SM et al. Randomized trial of genotype-guided versus standard warfarin dosing in patients initiating oral anticoagulation. Circulation 116(22), 2563-2570 (2007).
-
(2007)
Circulation
, vol.116
, Issue.22
, pp. 2563-2570
-
-
Anderson, J.L.1
Horne, B.D.2
Stevens, S.M.3
-
13
-
-
79959189730
-
A randomized controlled trial of genotype-based coumadin initiation
-
Burmester JK, Berg RL, Yale SH et al. A randomized controlled trial of genotype-based coumadin initiation. Genet. Med. 13(6), 509-518 (2011).
-
(2011)
Genet. Med.
, vol.13
, Issue.6
, pp. 509-518
-
-
Burmester, J.K.1
Berg, R.L.2
Yale, S.H.3
-
14
-
-
21144448879
-
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
-
Rieder MJ, Reiner AP, Gage BF et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N. Engl. J. Med. 352(22), 2285-2293 (2005).
-
(2005)
N. Engl. J. Med.
, vol.352
, Issue.22
, pp. 2285-2293
-
-
Rieder, M.J.1
Reiner, A.P.2
Gage, B.F.3
-
15
-
-
51649110496
-
A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
-
Cooper GM, Johnson JA, Langaee TY et al. A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood 112(4), 1022-1027 (2008).
-
(2008)
Blood
, vol.112
, Issue.4
, pp. 1022-1027
-
-
Cooper, G.M.1
Johnson, J.A.2
Langaee, T.Y.3
-
16
-
-
78149256303
-
Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese
-
Cha PC, Mushiroda T, Takahashi A et al. Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese. Hum. Mol. Genet. 19(23), 4735-4744 (2011).
-
(2011)
Hum. Mol. Genet.
, vol.19
, Issue.23
, pp. 4735-4744
-
-
Cha, P.C.1
Mushiroda, T.2
Takahashi, A.3
-
17
-
-
63449117825
-
A genome-wide association study confirms VKORC1 CYP2C9 and CYP4F2 as principal genetic determinants of warfarin dose
-
Takeuchi F, McGinnis R, Bourgeois S et al. A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet. 5(3), E1000433 (2009).
-
(2009)
Plos Genet.
, vol.5
, Issue.3
-
-
Takeuchi, F.1
McGinnis, R.2
Bourgeois, S.3
-
18
-
-
44949234553
-
Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans
-
Limdi NA, Arnett DK, Goldstein JA et al. Influence of CYP2C9 and VKORC1 on warfarin dose, anticoagulation attainment and maintenance among European-Americans and African-Americans. Pharmacogenomics 9(5), 511-526 (2008).
-
(2008)
Pharmacogenomics
, vol.9
, Issue.5
, pp. 511-526
-
-
Limdi, N.A.1
Arnett, D.K.2
Goldstein, J.A.3
-
19
-
-
0036914221
-
Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance
-
Scordo MG, Pengo V, Spina E et al. Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance. Clin. Pharmacol. Ther. 72(6), 702-710 (2002).
-
(2002)
Clin. Pharmacol. Ther.
, vol.72
, Issue.6
, pp. 702-710
-
-
Scordo, M.G.1
Pengo, V.2
Spina, E.3
-
20
-
-
0031807762
-
Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes
-
Takahashi H, Kashima T, Nomizo Y et al. Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes. Clin. Pharmacol. Ther. 63(5), 519-528 (1998).
-
(1998)
Clin. Pharmacol. Ther.
, vol.63
, Issue.5
, pp. 519-528
-
-
Takahashi, H.1
Kashima, T.2
Nomizo, Y.3
-
21
-
-
77949873283
-
Genetic and clinical predictors of warfarin dose requirements in African Americans
-
Cavallari LH, Langaee TY, Momary KM et al. Genetic and clinical predictors of warfarin dose requirements in African Americans. Clin. Pharmacol. Ther. 87(4), 459-464 (2010).
-
(2010)
Clin. Pharmacol. Ther.
, vol.87
, Issue.4
, pp. 459-464
-
-
Cavallari, L.H.1
Langaee, T.Y.2
Momary, K.M.3
-
22
-
-
38349126516
-
Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on warfarin
-
Limdi NA, McGwin G, Goldstein JA et al. Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on warfarin. Clin. Pharmacol. Ther. 83(2), 312-321 (2007).
-
(2007)
Clin. Pharmacol. Ther.
, vol.83
, Issue.2
, pp. 312-321
-
-
Limdi, N.A.1
McGwin, G.2
Goldstein, J.A.3
-
23
-
-
10744228888
-
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
-
Rost S, Fregin A, Ivaskevicius V et al. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2. Nature 427(6974), 537-541 (2004).
-
(2004)
Nature
, vol.427
, Issue.6974
, pp. 537-541
-
-
Rost, S.1
Fregin, A.2
Ivaskevicius, V.3
-
24
-
-
11244332058
-
A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
-
D'Andrea G, D'Ambrosio RL, Di Perna P et al. A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin. Blood 105(2), 645-649 (2005).
-
(2005)
Blood
, vol.105
, Issue.2
, pp. 645-649
-
-
D'Andrea, G.1
D'Ambrosio, R.L.2
Di Perna, P.3
-
25
-
-
51649084617
-
Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement
-
Wang D, Chen H, Momary KM et al. Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement. Blood 112(4), 1013-1021 (2008).
-
(2008)
Blood
, vol.112
, Issue.4
, pp. 1013-1021
-
-
Wang, D.1
Chen, H.2
Momary, K.M.3
-
26
-
-
77952570889
-
Warfarin pharmacogenetics: A single VKORC1 polymorphism is predictive of dose across 3 racial groups
-
Limdi NA, Wadelius M, Cavallari L et al. Warfarin pharmacogenetics: A single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood 115(18), 3827-3834 (2010).
-
(2010)
Blood
, vol.115
, Issue.18
, pp. 3827-3834
-
-
Limdi, N.A.1
Wadelius, M.2
Cavallari, L.3
-
27
-
-
84872597479
-
Coumadin®, package insert
-
Princeton, NJ, USA
-
Coumadin®, package insert. Bristol-Myers Squibb, Princeton, NJ, USA.
-
Bristol-Myers Squibb
-
-
-
28
-
-
1542782670
-
Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin
-
Gage BF, Eby C, Milligan PE et al. Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin. Thromb. Haemost. 91(1), 87-94 (2004).
-
(2004)
Thromb. Haemost.
, vol.91
, Issue.1
, pp. 87-94
-
-
Gage, B.F.1
Eby, C.2
Milligan, P.E.3
-
29
-
-
77951498679
-
Integration of genetic, clinical, and INR data to refine warfarin dosing
-
Lenzini P, Wadelius M, Kimmel S et al. Integration of genetic, clinical, and INR data to refine warfarin dosing. Clin. Pharmacol. Ther. 87(5), 572-578 (2010).
-
(2010)
Clin. Pharmacol. Ther.
, vol.87
, Issue.5
, pp. 572-578
-
-
Lenzini, P.1
Wadelius, M.2
Kimmel, S.3
-
30
-
-
84863012482
-
Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy
-
Horne BD, Lenzini PA, Wadelius M et al. Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy. Thromb. Haemost. 107(2), 232-240 (2012).
-
(2012)
Thromb. Haemost.
, vol.107
, Issue.2
, pp. 232-240
-
-
Horne, B.D.1
Lenzini, P.A.2
Wadelius, M.3
-
31
-
-
0033608466
-
Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
-
Aithal GP, Day CP, Kesteven PJ, Daly AK. Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 353(9154), 717-719 (1999).
-
(1999)
Lancet
, vol.353
, Issue.9154
, pp. 717-719
-
-
Aithal, G.P.1
Day, C.P.2
Kesteven, P.J.3
Daly, A.K.4
-
32
-
-
62549143945
-
Influence of CYP2C9 genotype on warfarin dose requirements - A systematic review and meta-analysis
-
Lindh JD, Holm L, Andersson ML, Rane A. Influence of CYP2C9 genotype on warfarin dose requirements - A systematic review and meta-analysis. Eur. J. Clin. Pharmacol. 65(4), 365-375 (2009).
-
(2009)
Eur. J. Clin. Pharmacol.
, vol.65
, Issue.4
, pp. 365-375
-
-
Lindh, J.D.1
Holm, L.2
Andersson, M.L.3
Rane, A.4
-
33
-
-
79151476272
-
Pharmacogenomics of warfarin dose requirements in Hispanics
-
Cavallari LH, Momary KM, Patel SR et al. Pharmacogenomics of warfarin dose requirements in Hispanics. Blood Cells Mol. Dis. 46(2), 147-150 (2011).
-
(2011)
Blood Cells Mol. Dis.
, vol.46
, Issue.2
, pp. 147-150
-
-
Cavallari, L.H.1
Momary, K.M.2
Patel, S.R.3
-
34
-
-
79951811694
-
The missing association: Sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans
-
Perera MA, Gamazon E, Cavallari LH et al. The missing association: Sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans. Clin. Pharmacol. Ther. 89(3), 408-415 (2011).
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, Issue.3
, pp. 408-415
-
-
Perera, M.A.1
Gamazon, E.2
Cavallari, L.H.3
-
35
-
-
55449100859
-
VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans
-
Limdi NA, Beasley TM, Crowley MR et al. VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans. Pharmacogenomics 9(10), 1445-1458 (2008).
-
(2008)
Pharmacogenomics
, vol.9
, Issue.10
, pp. 1445-1458
-
-
Limdi, N.A.1
Beasley, T.M.2
Crowley, M.R.3
-
36
-
-
33645563532
-
Population variation in VKORC1 haplotype structure
-
Marsh S, King CR, Porche-Sorbet RM, Scott-Horton TJ, Eby CS. Population variation in VKORC1 haplotype structure. J. Thromb. Haemost. 4(2), 473-474 (2006).
-
(2006)
J. Thromb. Haemost.
, vol.4
, Issue.2
, pp. 473-474
-
-
Marsh, S.1
King, C.R.2
Porche-Sorbet, R.M.3
Scott-Horton, T.J.4
Eby, C.S.5
-
37
-
-
77949874684
-
A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans
-
Voora D, Koboldt DC, King CR et al. A polymorphism in the VKORC1 regulator calumenin predicts higher warfarin dose requirements in African Americans. Clin. Pharmacol. Ther. 87(4), 445-451 (2010).
-
(2010)
Clin. Pharmacol. Ther.
, vol.87
, Issue.4
, pp. 445-451
-
-
Voora, D.1
Koboldt, D.C.2
King, C.R.3
-
38
-
-
84855921127
-
Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans
-
Cavallari LH, Perera M, Wadelius M et al. Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans. Pharmacogenet. Genomics 22(2), 152-158 (2012).
-
(2012)
Pharmacogenet. Genomics
, vol.22
, Issue.2
, pp. 152-158
-
-
Cavallari, L.H.1
Perera, M.2
Wadelius, M.3
-
39
-
-
42149188553
-
CYP4F2 genetic variant alters required warfarin dose
-
Caldwell MD, Awad T, Johnson JA et al. CYP4F2 genetic variant alters required warfarin dose. Blood 111(8), 4106-4112 (2008).
-
(2008)
Blood
, vol.111
, Issue.8
, pp. 4106-4112
-
-
Caldwell, M.D.1
Awad, T.2
Johnson, J.A.3
-
40
-
-
33845660774
-
The epidemiology of pulmonary embolism: Racial contrasts in incidence and in-hospital case fatality
-
Schneider D, Lilienfeld DE, Im W. The epidemiology of pulmonary embolism: Racial contrasts in incidence and in-hospital case fatality. J. Natl Med. Assoc. 98(12), 1967-1972 (2006).
-
(2006)
J. Natl Med. Assoc.
, vol.98
, Issue.12
, pp. 1967-1972
-
-
Schneider, D.1
Lilienfeld, D.E.2
Im, W.3
-
41
-
-
79751531393
-
Heart disease and stroke statistics - 2011 update: A report from the American heart association
-
Roger VL, Go AS, Lloyd-Jones DM et al. Heart disease and stroke statistics - 2011 update: A report from the American Heart Association. Circulation 123(4), E18-E209 (2011).
-
(2011)
Circulation
, vol.123
, Issue.4
-
-
Roger, V.L.1
Go, A.S.2
Lloyd-Jones, D.M.3
-
42
-
-
33748615153
-
Racial and gender differences in the incidence of recurrent venous thromboembolism
-
White RH, Dager WE, Zhou H, Murin S. Racial and gender differences in the incidence of recurrent venous thromboembolism. Thromb. Haemost. 96(3), 267-273 (2006).
-
(2006)
Thromb. Haemost.
, vol.96
, Issue.3
, pp. 267-273
-
-
White, R.H.1
Dager, W.E.2
Zhou, H.3
Murin, S.4
-
43
-
-
3242753184
-
Excess stroke in Mexican Americans compared with non-Hispanic Whites: The brain attack surveillance in corpus christi project
-
Morgenstern LB, Smith MA, Lisabeth LD et al. Excess stroke in Mexican Americans compared with non-Hispanic Whites: The brain attack surveillance in corpus christi project. Am. J. Epidemiol. 160(4), 376-383 (2004).
-
(2004)
Am. J. Epidemiol.
, vol.160
, Issue.4
, pp. 376-383
-
-
Morgenstern, L.B.1
Smith, M.A.2
Lisabeth, L.D.3
-
44
-
-
46249110258
-
Ethnic disparities in stroke and hypertension among women: The BASIC project
-
Lisabeth LD, Smith MA, Sanchez BN, Brown DL. Ethnic disparities in stroke and hypertension among women: The BASIC project. Am. J. Hypertens. 21(7), 778-783 (2008).
-
(2008)
Am. J. Hypertens.
, vol.21
, Issue.7
, pp. 778-783
-
-
Lisabeth, L.D.1
Smith, M.A.2
Sanchez, B.N.3
Brown, D.L.4
-
45
-
-
28944450071
-
Stroke burden in Mexican Americans: The impact of mortality following stroke
-
Lisabeth LD, Risser JM, Brown DL et al. Stroke burden in Mexican Americans: The impact of mortality following stroke. Ann. Epidemiol. 16(1), 33-40 (2006).
-
(2006)
Ann. Epidemiol.
, vol.16
, Issue.1
, pp. 33-40
-
-
Lisabeth, L.D.1
Risser, J.M.2
Brown, D.L.3
-
46
-
-
62249164280
-
Effects of race and ethnicity on the incidence of venous thromboembolism
-
White RH, Keenan CR. Effects of race and ethnicity on the incidence of venous thromboembolism. Thromb. Res. 123(Suppl. 4), S11-S17 (2009).
-
(2009)
Thromb. Res.
, vol.123
, Issue.SUPPL. 4
-
-
White, R.H.1
Keenan, C.R.2
-
47
-
-
46149098096
-
Long-range LD can confound genome scans in admixed populations
-
132-135; author reply
-
Price AL, Weale ME, Patterson N et al. Long-range LD can confound genome scans in admixed populations. Am. J. Hum. Genet. 83(1), 132-135; author reply 135-139 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.83
, Issue.1
, pp. 135-139
-
-
Price, A.L.1
Weale, M.E.2
Patterson, N.3
-
48
-
-
34547138943
-
Evaluation of genetic factors for warfarin dose prediction
-
Caldwell MD, Berg RL, Zhang KQ et al. Evaluation of genetic factors for warfarin dose prediction. Clin. Med. Res. 5(1), 8-16 (2007).
-
(2007)
Clin. Med. Res.
, vol.5
, Issue.1
, pp. 8-16
-
-
Caldwell, M.D.1
Berg, R.L.2
Zhang, K.Q.3
-
49
-
-
37349123273
-
Factors influencing warfarin dose requirements in African-Americans
-
Momary KM, Shapiro NL, Viana MA et al. Factors influencing warfarin dose requirements in African-Americans. Pharmacogenomics 8(11), 1535-1544 (2007).
-
(2007)
Pharmacogenomics
, vol.8
, Issue.11
, pp. 1535-1544
-
-
Momary, K.M.1
Shapiro, N.L.2
Viana, M.A.3
-
50
-
-
34548822941
-
Genetic-based dosing in orthopaedic patients beginning warfarin therapy
-
Millican E, Jacobsen-Lenzini PA, Milligan PE et al. Genetic-based dosing in orthopaedic patients beginning warfarin therapy. Blood 110(5), 1511-1515 (2007).
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1511-1515
-
-
Millican, E.1
Jacobsen-Lenzini, P.A.2
Milligan, P.E.3
-
51
-
-
49949106034
-
Dosing algorithms to predict warfarin maintenance dose in Caucasians and African Americans
-
Schelleman H, Chen J, Chen Z et al. Dosing algorithms to predict warfarin maintenance dose in Caucasians and African Americans. Clin. Pharmacol. Ther. 84(3), 332-339 (2008).
-
(2008)
Clin. Pharmacol. Ther.
, vol.84
, Issue.3
, pp. 332-339
-
-
Schelleman, H.1
Chen, J.2
Chen, Z.3
-
52
-
-
79956119832
-
Contribution of VKORC1 and CYP2C9 polymorphisms in the interethnic variability of warfarin dose in Malaysian populations
-
Gan GG, Phipps ME, Lee MM et al. Contribution of VKORC1 and CYP2C9 polymorphisms in the interethnic variability of warfarin dose in Malaysian populations. Ann. Hematol. 90(6), 635-641 (2011).
-
(2011)
Ann. Hematol.
, vol.90
, Issue.6
, pp. 635-641
-
-
Gan, G.G.1
Phipps, M.E.2
Lee, M.M.3
-
53
-
-
4544288090
-
Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose
-
Zhao F, Loke C, Rankin SC et al. Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose. Clin. Pharmacol. Ther. 76(3), 210-219 (2004).
-
(2004)
Clin. Pharmacol. Ther.
, vol.76
, Issue.3
, pp. 210-219
-
-
Zhao, F.1
Loke, C.2
Rankin, S.C.3
-
54
-
-
0030061531
-
Factors determining the maintenance dose of warfarin in Chinese patients
-
Yu HC, Chan TY, Critchley JA, Woo KS. Factors determining the maintenance dose of warfarin in Chinese patients. Q JM 89(2), 127-135 (1996).
-
(1996)
QJM
, vol.89
, Issue.2
, pp. 127-135
-
-
Yu, H.C.1
Chan, T.Y.2
Critchley, J.A.3
Woo, K.S.4
-
55
-
-
0029667388
-
Global patterns of linkage disequilibrium at the CD4 locus and modern human origins
-
Tishkoff SA, Dietzsch E, Speed W et al. Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science 271(5254), 1380-1387 (1996).
-
(1996)
Science
, vol.271
, Issue.5254
, pp. 1380-1387
-
-
Tishkoff, S.A.1
Dietzsch, E.2
Speed, W.3
-
56
-
-
0034921210
-
Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans
-
Dickmann LJ, Rettie AE, Kneller MB et al. Identification and functional characterization of a new CYP2C9 variant (CYP2C9. *5) expressed among African Americans. Mol. Pharmacol. 60(2), 382-387 (2001).
-
(2001)
Mol. Pharmacol.
, vol.60
, Issue.2
, pp. 382-387
-
-
Dickmann, L.J.1
Rettie, A.E.2
Kneller, M.B.3
-
57
-
-
27444433157
-
CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population
-
Allabi AC, Gala JL, Horsmans Y. CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population. Pharmacogenet. Genomics 15(11), 779-786 (2005).
-
(2005)
Pharmacogenet. Genomics
, vol.15
, Issue.11
, pp. 779-786
-
-
Allabi, A.C.1
Gala, J.L.2
Horsmans, Y.3
-
58
-
-
4243052841
-
Discovery of new potentially defective alleles of human CYP2C9
-
Blaisdell J, Jorge-Nebert LF, Coulter S et al. Discovery of new potentially defective alleles of human CYP2C9. Pharmacogenetics 14(8), 527-537 (2004).
-
(2004)
Pharmacogenetics
, vol.14
, Issue.8
, pp. 527-537
-
-
Blaisdell, J.1
Jorge-Nebert, L.F.2
Coulter, S.3
-
59
-
-
3543006619
-
Functional impact of CYP2C95, CYP2C96, CYP2C98, and CYP2C911 in vivo among black Africans
-
Allabi AC, Gala JL, Horsmans Y et al. Functional impact of CYP2C95, CYP2C96, CYP2C98, and CYP2C911 in vivo among black Africans. Clin. Pharmacol. Ther. 76(2), 113-118 (2004).
-
(2004)
Clin. Pharmacol. Ther.
, vol.76
, Issue.2
, pp. 113-118
-
-
Allabi, A.C.1
Gala, J.L.2
Horsmans, Y.3
-
60
-
-
84862796555
-
Decreased warfarin clearance with the CYP2C9 R150H (.*8) polymorphism
-
Lui Y, Hyun-Young J, Takahashi H et al. Decreased warfarin clearance with the CYP2C9 R150H (*8) polymorphism. Clin. Pharmacol. Ther. 91(4), 660-665 (2012).
-
(2012)
Clin. Pharmacol. Ther.
, vol.91
, Issue.4
, pp. 660-665
-
-
Lui, Y.1
Hyun-Young, J.2
Takahashi, H.3
-
61
-
-
79960777339
-
Novel CYP2C9 and VKORC1 gene variants associated with warfarin dosage variability in the South African black population
-
Mitchell C, Gregersen N, Krause A. Novel CYP2C9 and VKORC1 gene variants associated with warfarin dosage variability in the South African black population. Pharmacogenomics 12(7), 953-963 (2011).
-
(2011)
Pharmacogenomics
, vol.12
, Issue.7
, pp. 953-963
-
-
Mitchell, C.1
Gregersen, N.2
Krause, A.3
-
62
-
-
66849132349
-
CYP4F2 is a vitamin K1 oxidase: An explanation for altered warfarin cose in carriers of the V433M variant
-
McDonald MG, Rieder MJ, Nakano M, Hsia CH, Rettie AE. CYP4F2 is a vitamin K1 oxidase: An explanation for altered warfarin cose in carriers of the V433M variant. Mol. Pharmacol. 75(6), 1337-1346 (2009).
-
(2009)
Mol. Pharmacol.
, vol.75
, Issue.6
, pp. 1337-1346
-
-
McDonald, M.G.1
Rieder, M.J.2
Nakano, M.3
Hsia, C.H.4
Rettie, A.E.5
-
63
-
-
2942627237
-
The inhibitory effect of calumenin on the vitamin K-dependent g-carboxylation system characterization of the system in normal and warfarin-resistant rats
-
Wajih N, Sane DC, Hutson SM, Wallin R. The inhibitory effect of calumenin on the vitamin K-dependent g-carboxylation system. Characterization of the system in normal and warfarin-resistant rats. J. Biol. Chem. 279(24), 25276-25283 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.24
, pp. 25276-25283
-
-
Wajih, N.1
Sane, D.C.2
Hutson, S.M.3
Wallin, R.4
-
64
-
-
79951682471
-
Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients
-
Shahin MH, Khalifa SI, Gong Y et al. Genetic and nongenetic factors associated with warfarin dose requirements in Egyptian patients. Pharmacogenet. Genomics 21(3), 130-135 (2011).
-
(2011)
Pharmacogenet. Genomics
, vol.21
, Issue.3
, pp. 130-135
-
-
Shahin, M.H.1
Khalifa, S.I.2
Gong, Y.3
-
65
-
-
4143112300
-
Compound heterozygous mutations in the g-glutamyl carboxylase gene cause combined deficiency of all vitamin K-dependent blood coagulation factors
-
Rost S, Fregin A, Koch D et al. Compound heterozygous mutations in the g-glutamyl carboxylase gene cause combined deficiency of all vitamin K-dependent blood coagulation factors. Br. J. Haematol. 126(4), 546-549 (2004).
-
(2004)
Br. J. Haematol.
, vol.126
, Issue.4
, pp. 546-549
-
-
Rost, S.1
Fregin, A.2
Koch, D.3
-
66
-
-
34248580622
-
Genotypes of vitamin K epoxide reductase, g-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients
-
Kimura R, Miyashita K, Kokubo Y et al. Genotypes of vitamin K epoxide reductase, g-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients. Thromb. Res. 120(2), 181-186 (2007).
-
(2007)
Thromb. Res.
, vol.120
, Issue.2
, pp. 181-186
-
-
Kimura, R.1
Miyashita, K.2
Kokubo, Y.3
-
67
-
-
27744516938
-
Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing
-
Chen LY, Eriksson N, Gwilliam R et al. Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing. Blood 106(10), 3673-3674 (2005).
-
(2005)
Blood
, vol.106
, Issue.10
, pp. 3673-3674
-
-
Chen, L.Y.1
Eriksson, N.2
Gwilliam, R.3
-
68
-
-
77958129007
-
G-glutamyl carboxylase and its influence on warfarin dose
-
King CR, Deych E, Milligan P et al. g-glutamyl carboxylase and its influence on warfarin dose. Thromb. Haemost. 104(4), 750-754 (2010).
-
(2010)
Thromb. Haemost.
, vol.104
, Issue.4
, pp. 750-754
-
-
King, C.R.1
Deych, E.2
Milligan, P.3
-
69
-
-
40449120615
-
Genetic determinants of response to warfarin during initial anticoagulation
-
Schwarz UI, Ritchie MD, Bradford Y et al. Genetic determinants of response to warfarin during initial anticoagulation. N. Engl. J. Med. 358(10), 999-1008 (2008).
-
(2008)
N. Engl. J. Med.
, vol.358
, Issue.10
, pp. 999-1008
-
-
Schwarz, U.I.1
Ritchie, M.D.2
Bradford, Y.3
-
70
-
-
42449136621
-
Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: Comparison with other equations
-
Wu AH, Wang P, Smith A et al. Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: Comparison with other equations. Pharmacogenomics 9(2), 169-178 (2008).
-
(2008)
Pharmacogenomics
, vol.9
, Issue.2
, pp. 169-178
-
-
Wu, A.H.1
Wang, P.2
Smith, A.3
-
71
-
-
77953745542
-
Comparative performance of gene-based warfarin dosing algorithms in a multiethnic population
-
Lubitz SA, Scott SA, Rothlauf EB et al. Comparative performance of gene-based warfarin dosing algorithms in a multiethnic population. J. Thromb. Haemost. 8(5), 1018-1026 (2010).
-
(2010)
J. Thromb. Haemost.
, vol.8
, Issue.5
, pp. 1018-1026
-
-
Lubitz, S.A.1
Scott, S.A.2
Rothlauf, E.B.3
-
72
-
-
80051689137
-
Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients
-
Huang RS, Johnatty SE, Gamazon ER et al. Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients. Clin. Cancer. Res. 17(16), 5490-5500 (2011).
-
(2011)
Clin. Cancer. Res.
, vol.17
, Issue.16
, pp. 5490-5500
-
-
Huang, R.S.1
Johnatty, S.E.2
Gamazon, E.R.3
-
74
-
-
79957993750
-
Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue
-
Innocenti F, Cooper GM, Stanaway IB et al. Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue. PLoS Genet. 7(5), E1002078 (2011).
-
(2011)
Plos Genet.
, vol.7
, Issue.5
-
-
Innocenti, F.1
Cooper, G.M.2
Stanaway, I.B.3
-
75
-
-
84864861048
-
Novel SNPs associated with warfarin dose in a large multicenter cohort of African Americans: Genome wide association study and replication results
-
Perera MA, Limdi NA, Cavallari L et al. Novel SNPs associated with warfarin dose in a large multicenter cohort of African Americans: Genome wide association study and replication results. Circulation 124(Suppl. 1), 15518 (2011).
-
(2011)
Circulation
, vol.124
, Issue.SUPPL. 1
, pp. 15518
-
-
Perera, M.A.1
Limdi, N.A.2
Cavallari, L.3
-
76
-
-
84859109645
-
The limits of genome-wide methods for pharmacogenomics
-
Gamazon ER, Skol AD, Perera MA. The limits of genome-wide methods for pharmacogenomics. Pharmacogenet. Genomics 22(4), 261-272 (2012).
-
(2012)
Pharmacogenet. Genomics
, vol.22
, Issue.4
, pp. 261-272
-
-
Gamazon, E.R.1
Skol, A.D.2
Perera, M.A.3
-
77
-
-
83055174032
-
Role of pharmacogenomics in the management of traditional and novel oral anticoagulants
-
Cavallari LH, Shin J, Perera MA. Role of pharmacogenomics in the management of traditional and novel oral anticoagulants. Pharmacotherapy 31(12), 1192-1207 (2011).
-
(2011)
Pharmacotherapy
, vol.31
, Issue.12
, pp. 1192-1207
-
-
Cavallari, L.H.1
Shin, J.2
Perera, M.A.3
-
78
-
-
84856699090
-
Executive summary: Antithrombotic therapy and prevention of thrombosis
-
9th Edition). American College of Chest Physicians evidence-based clinical practice guidelines
-
Guyatt GH, Akl EA, Crowther M, Gutterman DD, Schunemann HJ. Executive summary: Antithrombotic therapy and prevention of thrombosis (9th Edition). American College of Chest Physicians evidence-based clinical practice guidelines. Chest 141(Suppl. 2), S7-S47 (2012).
-
(2012)
Chest
, vol.141
, Issue.SUPPL. 2
-
-
Guyatt, G.H.1
Akl, E.A.2
Crowther, M.3
Gutterman, D.D.4
Schunemann, H.J.5
-
79
-
-
39449137238
-
Pharmacogenetic testing of CYP2C9 and VKORC1 alleles for warfarin
-
Flockhart DA, O'Kane D, Williams MS et al. Pharmacogenetic testing of CYP2C9 and VKORC1 alleles for warfarin. Genet. Med. 10(2), 139-150 (2008).
-
(2008)
Genet. Med.
, vol.10
, Issue.2
, pp. 139-150
-
-
Flockhart, D.A.1
O'Kane, D.2
Williams, M.S.3
-
80
-
-
39449086981
-
CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: A prospective randomized controlled study
-
Caraco Y, Blotnick S, Muszkat M. CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: A prospective randomized controlled study. Clin. Pharmacol. Ther. 83(3), 460-470 (2008).
-
(2008)
Clin. Pharmacol. Ther.
, vol.83
, Issue.3
, pp. 460-470
-
-
Caraco, Y.1
Blotnick, S.2
Muszkat, M.3
-
81
-
-
77953304931
-
Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo warfarin effectiveness study)
-
Epstein RS, Moyer TP, Aubert RE et al. Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo warfarin effectiveness study). J. Am. Coll. Cardiol. 55(25), 2804-2812 (2010).
-
(2010)
J. Am. Coll. Cardiol.
, vol.55
, Issue.25
, pp. 2804-2812
-
-
Epstein, R.S.1
Moyer, T.P.2
Aubert, R.E.3
-
82
-
-
78349294600
-
Statistical design of personalized medicine interventions: The clarification of optimal anticoagulation through genetics (coag) trial
-
French B, Joo J, Geller NL et al. Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial. Trials 11, 108 (2010).
-
(2010)
Trials
, vol.11
, Issue.108
-
-
French, B.1
Joo, J.2
Geller, N.L.3
-
83
-
-
80052962391
-
Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing
-
Johnson JA, Gong L, Whirl-Carrillo M et al. Clinical pharmacogenetics implementation consortium guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing. Clin. Pharmacol. Ther. 90(4), 625-629 (2011).
-
(2011)
Clin. Pharmacol. Ther.
, vol.90
, Issue.4
, pp. 625-629
-
-
Johnson, J.A.1
Gong, L.2
Whirl-Carrillo, M.3
|