Evaluation of pain in intravitreal bevacizumab injections

Current Eye Research

Volumn 37, Issue 9, 2012, Pages 813-817

  Moisseiev, Elad ^a   Regenbogen, Michael ^a   Bartfeld, Yael ^a   Barak, Adiel ^a  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Bevacizumab; Intravitreal injection; Pain; Quadrant; Visual Analog Score

Indexed keywords

BEVACIZUMAB; CIPROFLOXACIN; ESCARAINE JELLY; LIDOCAINE; RANIBIZUMAB; UNCLASSIFIED DRUG;

ADULT; AGED; CORRELATION ANALYSIS; DIABETES MELLITUS; DIABETIC MACULAR EDEMA; DIABETIC RETINOPATHY; FEMALE; HUMAN; INJECTION SITE; INJECTION SITE PAIN; LENS; MAJOR CLINICAL STUDY; MALE; PAIN ASSESSMENT; PATIENT COMPLIANCE; PRIORITY JOURNAL; RETINA BLOOD VESSEL OCCLUSION; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA CYSTOID EDEMA; RETINA NEOVASCULARIZATION; REVIEW; TREATMENT INDICATION; VISUAL ANALOG SCALE;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL, HUMANIZED; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTRAVITREAL INJECTIONS; MALE; MIDDLE AGED; PAIN; PAIN MEASUREMENT; RETINAL DISEASES; RETROSPECTIVE STUDIES;

EID: 84864843872     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2012.681335     Document Type: Review

References (30)

1. Yau GL, Jackman CS, Hooper PL, Sheidow TG. Intravitreal injection anesthesia-comparison of different topical agents: A prospective randomized controlled trial. Am J Ophthalmol 2011;151:333-337.
2. Gunther JB, Altaweel MM. Bevacizumab (Avastin) for the treatment of ocular disease. Surv Ophthalmol 2009;54:372-400.
3. Rosenfeld PJ, Brown DM, Heier JS et al.; MARINA Study Group. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006;355:1419-1431.
4. Brown DM, Kaiser PK, Michels M et al.; ANCHOR Study Group. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med 2006;355:1432-1444.
5. Elman MJ, Aiello LP, Beck RW et al.; Diabetic Retinopathy Clinical Research Network. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 2010;117:1064-1077.e35.
6. Mitchell P, Bandello F, Schmidt-Erfurth U et al.; RESTORE study group. The RESTORE study: Ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema. Ophthalmology 2011;118:615-625.
7. Campochiaro PA, Heier JS, Feiner L et al.; BRAVO Investigators. Ranibizumab for macular edema following branch retinal vein occlusion: Six-month primary end point results of a phase III study. Ophthalmology 2010;117:1102-1112.e1.
8. Ciulla TA, Rosenfeld PJ. Anti-vascular endothelial growth factor therapy for neovascular ocular diseases other than age-related macular degeneration. Curr Opin Ophthalmol 2009;20:166-174.
9. Martin DF, Maguire MG, Ying GS, Grunwald JE, Fine SL, Jaffe GJ; CATT Research Group. Ranibizumab and bevacizumab for neovascular age-related macular degeneration. N Engl J Med 2011;364:1897-1908.
10. Peyman GA, Lad EM, Moshfeghi DM. Intravitreal injection of therapeutic agents. Retina (Philadelphia, Pa) 2009;29:875-912.
11. Heimann H. (2007). Intravitreal injections: TECHNIQUES and sequelae. In: HOLZ FG, Spaide RF, eds. Medical Retina (Essentials in Ophthalmology). 1st ed. Berlin: SPRINGER-Verlag Berlin Heidelberg, 67-87.
12. Prenner JL. Anesthesia for intravitreal injection. Retina (Philadelphia, Pa) 2011;31:433-434.
13. Blaha GR, Tilton EP, Barouch FC, Marx JL. Randomized trial of anesthetic methods for intravitreal injections. Retina (Philadelphia, Pa) 2011;31:535-539.
14. Cintra LP, Lucena LR, Da Silva JA, Costa RA, Scott IU, Jorge R. Comparative study of analgesic effectiveness using three different anesthetic techniques for intravitreal injection of bevacizumab. Ophthalmic Surg Lasers Imaging 2009;40:13-18.
15. LaHood BR, Sherwood D, Suter A. Comparative assessment of the effectiveness of anaesthesia for intravitreal bevacizumab injection. Clin Experiment Ophthalmol 2011;39:184-185.
16. Kaderli B, Avci R. Comparison of topical and subconjunctival anesthesia in intravitreal injection administrations. Eur J Ophthalmol 2006;16:718-721.
17. Kozak I, Cheng L, Freeman WR. Lidocaine gel anesthesia for intravitreal drug administration. Retina (Philadelphia, Pa) 2005;25:994-998.
18. Rodrigues EB, Grumann A Jr, Penha FM et al. Effect of needle type and injection technique on pain level and vitreal reflux in intravitreal injection. J Ocul Pharmacol Ther 2011;27:197-203.
19. Knecht PB, Michels S, Sturm V, Bosch MM, Menke MN. Tunnelled versus straight intravitreal injection: Intraocular pressure changes, vitreous reflux, and patient discomfort. Retina (Philadelphia, Pa) 2009;29:1175-1181.
20. Woods CA, Cumming B. The impact of test medium on use of visual analogue scales. Eye Contact Lens 2009;35:6-10.
21. Johnson C. Measuring Pain. Visual Analog Scale Versus Numeric Pain Scale: WHAT is the Difference J Chiropr Med 2005;4:43-44.
22. Breivik EK, Björnsson GA, Skovlund E. A comparison of pain rating scales by sampling from clinical trial data. Clin J Pain 2000;16:22-28.
23. Salo D, Eget D, Lavery RF, Garner L, Bernstein S, Tandon K. Can patients accurately read a visual analog pain scale Am J Emerg Med 2003;21:515-519.
24. Jacobi PC, Dietlein TS, Jacobi FK. A comparative study of topical vs retrobulbar anesthesia in complicated cataract surgery. Arch Ophthalmol 2000;118:1037-1043.
25. Crandall AS, Zabriskie NA, Patel BC et al. A comparison of patient comfort during cataract surgery with topical anesthesia versus topical anesthesia and intracameral lidocaine. Ophthalmology 1999;106:60-66.
26. Chiambaretta F, Creuzot-Garcher C, Pilon F et al. [Ocular tolerance of a new formulation of nonpreserved diclofenac]. J Fr Ophtalmol 2004;27:739-744.
27. Moisseiev E, Varssano D. Comparison of ocular tolerability between preserved and preservative-free diclofenac sodium drops. J Ocul Pharmacol Ther 2011;27:333-337.
28. He J, Bazan NG, Bazan HE. Mapping the entire human corneal nerve architecture. Exp Eye Res 2010;91:513-523.
29. Cousen P, Cackett P, Bennett H, Swa K, Dhillon B. Tear production and corneal sensitivity in diabetes. J Diabetes Complicat 2007;21:371-373.
30. Tavakoli M, Kallinikos PA, Efron N, Boulton AJ, Malik RA. Corneal sensitivity is reduced and relates to the severity of neuropathy in patients with diabetes. Diabetes Care 2007;30:1895-1897.