Ocular tolerance of a new formulation of nonpreserved diclofenac;Intérêt d'une nouvelle formulation de diclofénac sans conservateur pour la surface oculaire

Journal Francais d'Ophtalmologie

Volumn 27, Issue 7, 2004, Pages 739-744

  Chiambaretta, F ^a   Creuzot Garcher, C ^b   Pilon, F ^a   Pouliquen, P ^c   Rebika, H ^c   Dubray, C ^d   Rigal, D ^a  

^a SERVICE DE RHUMATOLOGIE   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

^c Laboratoires Thea   (France)

^d CRNH AUVERGNE   (France)

Author keywords

Ocular toxicity; Phase I; Preservative; Thiomersal

Indexed keywords

ABAK; DICLOABAK; DICLOFENAC; THIOMERSAL;

ADULT; ARTICLE; BIOMICROSCOPY; BURNING SENSATION; CLINICAL TRIAL; CONJUNCTIVITIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG FORMULATION; DRUG STABILITY; DRUG TOLERABILITY; DRY EYE; EYE DISEASE; EYE IRRITATION; EYE TOXICITY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; VISUAL ANALOG SCALE;

EID: 4744366389     PISSN: 01815512     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0181-5512(04)96208-0     Document Type: Article

References (25)

1. Fabian E, Von Denffer H, Wertheimer R. Diclofenac eye drops to maintain mydriasis during extracapsular cataract extraction. Ophthalmo-Chirurgie, 1991;3:115-9.
2. Ertürk H, Öxçetin H, Avci R. Diclofenac sodium for the prevention of surgically induced miosis. Eur J Implant Refract Surg, 1991;3:55-7.
3. Antcliff RJ, Trew DR. The maintenance of per-operative mydriasis in phacoemulsification with topical diclofenac sodium. Eye, 1997;11:389-91.
4. Rossetti L, Bujtar E, Castoldi D, Torrazza C, Orzalesi N. Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery. J Cataract Refract Surg, 1996;22:794-9.
5. Miyake K, Masuda K, Shirato S, Oshika T, Eguchi K, Hoshi H, et al. Comparison of diclofenac and fluorometholone in preventing cystoid macular edema after small incision cataract surgery: a multicentered prospective trial. Jpn J Ophthalmol, 2000;44:58-67.
6. Othenin-Girard P, Tritten JJ, Rittet N, Herbort CP. Dexamethasone versus diclofenac sodium eyedrops to treat inflammation after cataract surgery. J Cataract Refract, 1994;20:9-12.
7. Roberts CW, Brennan KM. A comparison of topical diclofenac with prednisolone for postcataract inflammation. Arch Ophthalmol, 1995;113:725-7.
8. Rossetti L, Bellucci R, Cillino S, Monreale D, Bonomi L, Ponte F, et al. Efficacy and safety of combined diclofenac 0.1% and gentamicin 0.3% eyedrops after phacoemulsification. J Cataract Refract Surg 1997;23:745-9.
9. Kent AR, Dubiner HB, Whitaker R, Mundorf TK, Stewart JA, Cate EA, et al. The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. Ophthalmic Surg Lasers, 1998;29:562-9.
10. Apt L, Voo I, Isenberg SJ. A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery. Ophthalmology, 1998;105:1448-54.
11. Snir M, Axer-Siegel R, Friling R, Weinberger D. Efficacy of diclofenac versus dexamethasone for treatment after strabismus surgery. Ophthalmology, 2000;107:1884-8.
12. Dadeya S, Kamlesh. Comparative evaluation of diclofenac and dexamethasone following strabismus surgery. J Pediatr Ophthalmol Strabismus, 2002;39:166-8.
13. Forster W, Ratkay I, Krueger R, Busse H. Topical diclofenac sodium after excimer laser phototherapeutic keratectomy. J Refract Surg, 1997;13:311-3.
14. Appiotti A, Gualdi L, Alberti M, Gualdi M. Comparative study of the analgesic efficacy of flurbiprofen and diclofenac in patients following excimer laser photorefractive keratectomy. Clin Ther, 1998;20:913-20.
15. Jayamanne DG, Fitt AW, Dayan M, Andrews RM, Mitchell KW, Griffiths PG. The effectiveness of topical diclofenac in relieving discomfort following traumatic corneal abrasions. Eye, 1997;11:9-83.
16. Tauber J, Raizman MB, Ostrov CS, Laibovitz RA, Abelson MB, Betts JG, et al. A multicenter comparison of the ocular efficacy and safety of diclofenac 0.1% solution with that of ketorolac 0.5% solution in patients with acute seasonal allergic conjunctivitis. J Ocul Pharmacol Ther, 1998;14:137-45.
17. D'Angelo G, Lambiase A, Cortes M, Sgrulletta R, Pasqualetti R, Lamagna A, et al. Preservative-free diclofenac sodium 0.1% for vernal keratoconjunctivitis. Graefes Arch Clin Exp Ophthalmol, 2003;241:192-5.
18. Struck HG, Schafer K, Foja C, Giessler C, Lautenschlager C. Effect of diclofenac and flurbiprofen on the course of inflammation after cataract extraction. Ophthalmologe, 1994;91:482-5.
19. Diestelhorst M, Schmidl B, Konen W, Mester U, Raj PS. Efficacy and tolerance of diclofenac sodium 0.1%, flurbiprofen 0.03%, and indomethacin 1.0% in controlling postoperative inflammation. J Cataract Refract Surg, 1996;22:788-93.
20. Kraff MC, Sanders DR, McGuigan L, Raanan MG. Inhibition of blood-aqueous humor barrier breakdown with diclofenac. Arch Ophthalmol, 1990;108:380-3.
21. Becquet F, Goldschild M, Moldovan MS, Ettaiche M, Gastaud P, Baudouin C. Histopathological effects of topical ophthalmic preservatives on rat corneoconjunctival surface. Curr Eye Res, 1998;17:419-25.
22. Debbasch C, Brignole F, Pisella PJ, Warnet JM, Rat P, Baudouin C. Quaternary ammoniums and other preservatives contribution in oxidative stress and apoptosis on Chang conjunctival cells. Invest Ophthalmol Vis Sci, 2001;42:642-52.
23. Congdon NG, Schein OD, von Kulajta P, Lubomski LH, Gilbert D, Katz J. Corneal complications associated with topical ophthalmic use of nonsteroidal antiinflammatory drugs. J Cataract Refract Surg, 2001;27:622-31.
24. Mester U, Lohmann C, Pleyer U, Steinkamp G, Völcker E, Kruger H, et al. A comparison of two different formulations of diclofenac sodium 0.1 % in the treatment of inflammation following cataract-intraocular lens surgery. Drugs 2002;3:143-51.
25. Hessemer V, Schmidt KG, Schartner H. Minimally inflammatory cataract surgery. Klin Monatsbl Augenheilkd, 1996;209:331-9.