Expression and Cellular Localization of Inducible Nitric Oxide Synthase in Lipopolysaccharide-treated Rat Kidneys

Journal of Histochemistry and Cytochemistry

Volumn 60, Issue 4, 2012, Pages 301-315

  Choi, Jae Youn ^a   Nam, Sun Ah ^a   Jin, Dong Chan ^a   Kim, Jin ^a   Cha, Jung Ho ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

enzyme histochemistry; immunohistochemistry; in situ reverse transcriptase polymerase chain reaction; inducible nitric oxide synthase; kidney; lipopolysaccharide; rat; transmission electron microscopy

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME HISTOCHEMISTRY; ENZYME LOCALIZATION; EPITHELIUM CELL; EXAMINATION; GLOMERULUS; IMMUNOHISTOCHEMISTRY; KIDNEY CELL; KIDNEY COLLECTING TUBULE; KIDNEY EPITHELIUM; MALE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; SPRAGUE DAWLEY RAT;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; IMMUNOHISTOCHEMISTRY; KIDNEY; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

RATTUS;

EID: 84864818798     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/0022155411436131     Document Type: Article

References (42)

1. Abdel-latief M,Garbe LA,Koch M,Ruther J.An epoxide hydrolase involved in the biosynthesis of an insect sex attractant and its use to localize the production site.Proc Natl Acad Sci U S A. 2008;105:8914-8919.
2. Ahn KY,Mohaupt MG,Madsen KM,Kone BC.In situ hybridization localization of mRNA encoding inducible nitric oxide synthase in rat kidney.Am J Physiol. 1994;267:F748-F757.
3. Bates TE,Loesch A,Burnstock G,Clark JB.Mitochondrial nitric oxide synthase: a ubiquitous regulator of oxidative phosphorylation?.Biochem Biophys Res Commun. 1996;218:40-44.
4. Buffoli B,Pechánová O,Kojsová S,Andriantsitohaina R,Giugno L,Bianchi R,Rezzani R.Provinol prevents CsA-induced nephrotoxicity by reducing reactive oxygen species, iNOS, and NF-κB expression.J Histochem Cytochem. 2005;53:1459-1468.
5. Cha JH,Woo SK,Han KH,Kim YH,Handler JS,Kim J,Kwon HM.Hydration status affects nuclear distribution of transcription factor tonicity responsive enhancer binding protein in rat kidney.J Am Soc Nephrol. 2001;12:2221-2230.
6. Doi K,Leelahavanichkul A,Yuen PS,Star RA.Animal models of sepsis and sepsis-induced kidney injury.J Clin Invest. 2009;119:2868-2878.
7. Elfering SL,Sarkela TM,Giulivi C.Biochemistry of mitochondrial nitric-oxide synthase.J Biol Chem. 2002;277:38079-38086.
8. Fellet AL,Balaszczuk AM,Arranz C,López-Costa JJ,Boveris A,Bustamante J.Autonomic regulation of pacemaker activity: role of heart nitric oxide synthases.Am J Physiol Heart Circ Physiol. 2006;291:H1246-H1254.
9. Forstermann U,Closs EI,Pollock JS,Nakane M,Schwarz P,Gath I,Kleinert H.Nitric oxide synthase isozymes characterization, purification, molecular cloning, and functions.Hypertension. 1994;23:1121-1131.
10. Fujihara CK,Mattar AL,Vieira JM,Malheiros DMAC,Noronha IDL,Goncalves ARR,Nucci GD,Zatz R.Evidence for the existence of two distinct functions for the inducible NO synthase in the rat kidney: effect of aminoguanidine in rats with 5/6 ablation.J Am Soc Nephrol. 2002;13:2278-2287.
11. Gabbott PL,Bacon SJ.Histochemical localization of NADPH-dependent diaphorase (nitric oxide synthase) activity in vascular endothelial cells in the rat brain.Neuroscience. 1993;57:79-95.
12. Ghafourifar P,Richter C.Nitric oxide synthase activity in mitochondria.FEBS Lett. 1997;418:291-296.
13. Ghafourifar P,Schenk U,Klein SD,Richter C.Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria: evidence for intramitochondrial peroxynitrite formation.J Biol Chem. 1999;274:31185-1188.
14. Heemskerk S,Masereeuw R,Russel FGM,Pickkers P.Selective iNOS inhibition for the treatment of sepsis-induced acute kidney injury.Nat Rev Nephrol. 2009;5:629-640.
15. Holmqvist B,Olsson CF,Svensson M-L,Svanborg C,Forsell J,Alm P.Expression of nitric oxide synthase isoforms in the mouse kidney: cellular localization and influence by lipopolysaccharide and Toll-like receptor 4.J Mol Hist. 2005;36:499-516.
16. Hope BT,Michael GJ,Knigge KM,Vincent SR.Neuronal NADPH diaphorase is a nitric oxide synthase.Proc Natl Acad Sci U S A. 1991;88:2811-2814.
17. Johnson RA,Freeman RH.Renin release in rats during blockade of nitric oxide synthesis.Am J Physiol. 1994;266:R1723-R1729.
18. Kipari T,Cailhier JF,Ferenbach D,Watson S,Houlberg K,Walbaum D,Clay S,Savill J,Hughes J.Nitric oxide is an important mediator of renal tubular epithelial cell death in vitro and in murine experimental hydronephrosis.Am J Pathol. 2006;169:388-399.
19. Lan HY,Mu W,Nikolic-Paterson DJ,Atkins RC.A novel, simple, reliable, and sensitive method for multiple immunoenzyme staining: use of microwave oven heating to block antibody crossreactivity and retrieve antigens.J Histochem Cytochem. 1995;43:97-102.
20. Lancaster JR.Simulation of the diffusion and reaction of endogenously produced nitric oxide.Proc Natl Acad Sci U S A. 1994;91:8137-8141.
21. Lau KS,Nakashima O,Aalund GR,Hogarth L,Ujiie K,Yuen J,Star RA.TNF-alpha and IFN-gamma induce expression of nitric oxide synthase in cultured rat medullary interstitial cells.Am J Physiol. 1995;269:F212-F217.
22. Lortie MJ,Ishizuka S,Schwartz D,Blantz RC.Bioactive products of arginine in sepsis: tissue and plasma composition after LPS and iNOS blockade.Am J Physiol Cell Physiol. 2000;278:C1191-C1199.
23. Madsen KM,Zhang L,Shamat A-RA,Siegfried S,Cha JH.Ultrastructural localization of osteopontin in the kidney: induction by lipopolysaccharide.J Am Soc Nephrol. 1997;8:1043-1053.
24. Meyer-Schwesinger C,Dehde S,von Ruffer C,Gatzemeier S,Klug P,Wenzel UO,Stahl RAK,Thaiss F,Meyer TN.Rho kinase inhibition attenuates LPS-induced renal failure in mice in part by attenuation of NF-κB p65 signaling.Am J Physiol Renal Physiol. 2009;296:F1088-F1099.
25. Pannabecker TL,Abbott DE,Dantzler WH.Three-dimensional functional reconstruction of inner medullary thin limbs of Henle's loop.Am J Physiol Renal Physiol. 2004;286:F38-F45.
26. Qi X,Guy J.Localization of NADPH diaphorase/nitric oxide synthase in the optic nerve of the normal guinea pig: a light and electron microscopic study.J Comp Neurol. 1996;370:396-404.
27. Sade K,Schwartz D,Wolman Y,Schwartz I,Chernichovski T,Blum M,Brazowski E,Keynan S,Raz I,Blantz RC, et al.Time course of lipopolysaccharide-induced nitric oxide synthase mRNA expression in rat glomeruli.J Lab Clin Med. 1999;134:471-477.
28. Sato M,Nakakura T,Ogushi Y,Akabane G,Kurabuchi S,Suzuki M,Tanaka S.Expression of a mammalian aquaporin 3 homolog in the anterior pituitary gonadotrophs of the tree frog, Hyla japonica.Cell Tissue Res. 2011;343:595-603.
29. Schrier RW,Wang W.Acute renal failure and sepsis.N Engl J Med. 2004;351:159-169.
30. Spessert R,Claassen M.Histochemical differentiation between nitric oxide synthase-related and -unrelated diaphorase activity in the rat olfactory bulb.Histochem J. 1998;30:41-50.
31. Spessert R,Layes E.Fixation conditions affect the intensity but not the pattern of NADPH-diaphorase staining as a marker for neuronal nitric oxide synthase in rat olfactory bulb.J Histochem Cytochem. 1994;42:1309-1315.
32. Tatoyan A,Giulivi C.Purification and characterization of a nitric-oxide synthase from rat liver mitochondria.J Biol Chem. 1998;273:11044-11048.
33. Taylor BS,Alarcon LH,Billiar TR.Inducible nitric oxide synthase in the liver: regulation and function.Biochemistry (Mosc). 1998;63:766-781.
34. Tojo A,Gross SS,Zhang L,Tisher CC,Schmidt HH,Wilcox CS,Madsen KM.Immunocytochemical localization of distinct isoforms of nitric oxide synthase in the juxtaglomerular apparatus of normal rat kidney.J Am Soc Nephrol. 1994;4:1438-1447.
35. Tracey WR,Nakane M,Pollock JS,Förstermann U.Nitric oxide synthases in neuronal cells, macrophages and endothelium are NADPH diaphorases, but represent only a fraction of total cellular NADPH diaphorase activity.Biochem Biophys Res Commun. 1993;195:1035-1040.
36. Uckert S,Stanarius A,Stief CG,Wolf G,Jonas U,Machtens S.Immunocytochemical distribution of nitric oxide synthase in the human seminal vesicle: a light and electron microscopical study.Urol Res. 2003;31:262-266.
37. Vodovotz Y,Russell D,Xie QW,Bogdan C,Nathan C.Vesicle membrane association of nitric oxide synthase in primary mouse macrophages.J Immunol. 1995;154:2914-2925.
38. Wolkow PP.Involvement and dual effects of nitric oxide in septic shock.Inflamm Res. 1998;47:152-166.
39. Yamaguchi N,Jesmin S,Zaedi S,Shimojo N,Maeda S,Gando S,Koyama A,Miyauchi T.Time-dependent expression of renal vaso-regulatory molecules in LPS-induced endotoxemia in rat.Peptides. 2006;27:2258-2270.
40. Young HM,Furness JB,Shuttleworth CW,Bredt DS,Snyder SH.Co-localization of nitric oxide synthase immunoreactivity and NADPH diaphorase staining in neurons of the guineapig intestine.Histochemistry. 1992;97:375-378.
41. Zhai X-Y,Fenton RA,Andreasen A,Thomsen JS,Christensen EI.Aquaporin-1 is not expressed in descending thin limbs of short-loop nephrons.J Am Soc Nephrol. 2007;18:2937-2944.
42. Zhai X-Y,Thomsen JS,Birn H,Kristoffersen IB,Andreasen A,Christensen EI.Three-dimensional reconstruction of the mouse nephron.J Am Soc Nephrol. 2006;17:77-88.