Analytical and semipreparative enantioseparation of 9-hydroxyrisperidone, the main metabolite of risperidone, using high-performance liquid chromatography and capillary electrophoresis. Validation and determination of enantiomeric purity

Journal of Chromatography A

Volumn 1163, Issue 1-2, 2007, Pages 228-236

  Danel, Cécile ^a   Barthélémy, Christine ^a   Azarzar, Dalila ^a   Robert, Hugues ^a   Bonte, Jean Paul ^a   Odou, Pascal ^a   Vaccher, Claude ^a  

^a UNIV LILLE   (France)

Author keywords

Acid glycoprotein; 9 Hydroxyrisperidone; Chiral capillary electrophoresis; Chiral liquid chromatography; Cyclodextrins; Enantiomeric purity; Polysaccharides; Risperidone; Semipreparative enantioseparation

Indexed keywords

CAPILLARY ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES; PHASE SEPARATION; POLYSACCHARIDES;

9-HYDROXYRISPERIDONE; CHIRAL CAPILLARY ELECTROPHORESIS; CHIRAL LIQUID CHROMATOGRAPHY; ENANTIOMERIC PURITY; RISPERIDONE; SEMIPREPARATIVE ENANTIOSEPARATION;

KETONES;

CYCLODEXTRIN; OROSOMUCOID; PALIPERIDONE; RISPERIDONE;

ANALYTIC METHOD; ARTICLE; CAPILLARY ELECTROPHORESIS; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, CAPILLARY; ISOXAZOLES; MOLECULAR STRUCTURE; PYRIMIDINES; REPRODUCIBILITY OF RESULTS; RISPERIDONE; STEREOISOMERISM;

EID: 34547869242     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.06.023     Document Type: Article

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