Brown adipose tissue and its relationship to bone structure in pediatric patients

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 8, 2012, Pages 2693-2698

  Ponrartana, Skorn ^a   Aggabao, Patricia C ^a   Hu, Houchun H ^a,b   Aldrovandi, Grace M ^a   Wren, Tishya A L ^a   Gilsanz, Vicente ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b University of Southern California   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADDUCTOR MUSCLE; ADOLESCENT; ADULT; ARTICLE; BODY HEIGHT; BODY WEIGHT; BONE STRUCTURE; BROWN ADIPOSE TISSUE; CHILD; CHILDHOOD CANCER; COMPUTER ASSISTED TOMOGRAPHY; CORTICAL BONE; CROSS-SECTIONAL STUDY; FEMALE; FEMUR; GENDER; HAMSTRING; HUMAN; MALE; POSITRON EMISSION TOMOGRAPHY; PRESCHOOL CHILD; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; SCHOOL CHILD; SKELETAL MUSCLE; SUBCUTANEOUS FAT;

ADIPOSE TISSUE, BROWN; ADOLESCENT; ADULT; BONE DEVELOPMENT; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; FEMUR; HUMANS; MALE; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; REGRESSION ANALYSIS;

EID: 84864793493     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-1589     Document Type: Article

References (25)

1. Cannon B, Nedergaard J 2004 Brown adipose tissue: function and physiological significance. Physiol Rev 84:277-359 (Pubitemid 38054374)
2. Gilsanz V, Chung SA, Jackson H, Dorey FJ, Hu HH2011 Functional brown adipose tissue is related to muscle volume in children and adolescents. J Pediatr 158:722-726
3. Gilsanz V, Smith ML, Goodarzian F, Kim M, Wren TA, Hu HH 2012 Changes in brown adipose tissue in boys and girls during childhood and puberty. J Pediatr 160:604-609.e601
4. Kajimura S, Seale P, Spiegelman BM 2010 Transcriptional control of brown fat development. Cell Metab 11:257-262
5. Farmer SR 2008 Brown fat and skeletal muscle: unlikely cousins? Cell 134:726-727
6. Calo E, Quintero-Estades JA, Danielian PS, Nedelcu S, Berman SD, Lees JA 2010 Rb regulates fate choice and lineage commitment in vivo. Nature 466:1110-1114
7. Thomas DM, Carty SA, Piscopo DM, Lee JS, Wang WF, Forrester WC, Hinds PW 2001 The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation. Mol Cell 8:303-316 (Pubitemid 32831548)
8. Fajas L, Egler V, Reiter R, Hansen J, Kristiansen K, Debril MB, Miard S, Auwerx J 2002 The retinoblastoma-histone deacetylase 3 complex inhibits PPARγ and adipocyte differentiation. Dev Cell 3:903-910 (Pubitemid 35460789)
9. Abdallah BM, Ding M, Jensen CH, Ditzel N, Flyvbjerg A, Jensen TG, Dagnaes-Hansen F, Gasser JA, Kassem M 2007 Dlk1/FA1 is a novel endocrine regulator of bone and fat mass and its serum level is modulated by growth hormone. Endocrinology 148:3111-3121 (Pubitemid 46996977)
10. Bredella MA, Fazeli PK, Freedman LM, Calder G, Lee H, Rosen CJ, Klibanski A 2012 Young women with cold-activated brown adipose tissue have higher bone mineral density and lower Pref-1 than women without brown adipose tissue: a study in women with anorexia nervosa, women recovered from anorexia nervosa, and normal-weight women. J Clin Endocrinol Metab 97:E584-E590
11. Hu HH, Chung SA, Nayak KS, Jackson HA, Gilsanz V 2011 Differential computed tomographic attenuation of metabolically active and inactive adipose tissues: preliminary findings. J Comput Assist Tomogr 35:65-71
12. Gelfand MJ, O'hara S M, Curtwright LA, Maclean JR 2005 Premedication to block [(18)F]FDG uptake in the brown adipose tissue of pediatric and adolescent patients. Pediatr Radiol 35:984-990
13. Pfannenberg C, Werner MK, Ripkens S, Stef I, Deckert A, Schmadl M, Reimold M, Häring HU, Claussen CD, Stefan N 2010 Impact of age on the relationships of brown adipose tissue with sex and adiposity in humans. Diabetes 59:1789-1793
14. Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, Nio-Kobayashi J, Iwanaga T, Miyagawa M, Kameya T, Nakada K, Kawai Y, Tsujisaki M 2009 High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 58:1526-1531
15. Lee P, Greenfield JR, Ho KK, Fulham MJ 2010 A critical appraisal of the prevalence and metabolic significance of brown adipose tissue in adult humans. Am J Physiol Endocrinol Metab 299:E601-E606
16. Kovanlikaya A, Loro ML, Hangartner TN, Reynolds RA, Roe TF, Gilsanz V 1996 Osteopenia in children: CT assessment. Radiology 198:781-784 (Pubitemid 26066298)
17. Seger RL, Cross RA, Rosen CJ, Causey RC, Gundberg CM, Carpenter TO, Chen TC, Halteman WA, Holick MF, Jakubas WJ, Keisler DH, Seger RM, Servello FA 2011 Investigating the mechanism for maintaining eucalcemia despite immobility and anuria in the hibernating American black bear (Ursus americanus). Bone 49:1205-1212
18. Frost HM 2003 Bone's mechanostat: a 2003 update. Anat Rec A Discov Mol Cell Evol Biol 275:1081-1101 (Pubitemid 37486785)
19. Fricke O, Schoenau E 2007 The 'Functional Muscle-Bone Unit': probing the relevance of mechanical signals for bone development in children and adolescents. Growth Horm IGF Res 17:1-9
20. Matsuoka T, Ahlberg PE, Kessaris N, Iannarelli P, Dennehy U, Richardson WD, McMahon AP, Koentges G 2005 Neural crest origins of the neck and shoulder. Nature 436:347-355 (Pubitemid 41059040)
21. Carmona MC, Hondares E, Rodríguez de la Concepción ML, Rodríguez-Sureda V, Peinado-Onsurbe J, Poli V, Iglesias R, Villarroya F, Giralt M 2005 Defective thermoregulation, impaired lipid metabolism, but preserved adrenergic induction of gene expression in brown fat of mice lacking C/EBPβ. Biochem J 389:47-56 (Pubitemid 40978006)
22. Zanotti S, Stadmeyer L, Smerdel-Ramoya A, Durant D, Canalis E 2009 Misexpression of CCAAT/enhancer binding protein β causes osteopenia. J Endocrinol 201:263-274
23. Motyl KJ, Rosen CJ 2011 Temperatures rising: brown fat and bone. Discov Med 11:179-185
24. Olmsted-Davis E, Gannon FH, Ozen M, Ittmann MM, Gugala Z, Hipp JA, Moran KM, Fouletier-Dilling CM, Schumara-Martin S, Lindsey RW, Heggeness MH, Brenner MK, Davis AR 2007 Hypoxic adipocytes pattern early heterotopic bone formation. Am J Pathol 170:620-632 (Pubitemid 47339399)
25. Egginton S, Fairney J, Bratcher J 2001 Differential effects of cold exposure on muscle fibre composition and capillary supply in hibernator and non-hibernator rodents. Exp Physiol 86:629-639 (Pubitemid 32910353)