Coronary microvascular dysfunction is associated with higher frequency of thin-cap fibroatheroma

Atherosclerosis

Volumn 223, Issue 2, 2012, Pages 384-388

  Dhawan, Saurabh S ^a   Corban, Michel T ^a   Nanjundappa, Ravi A ^a   Eshtehardi, Parham ^a   McDaniel, Michael C ^a   Kwarteng, Collins A ^a   Samady, Habib ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atherosclerosis; Coronary flow reserve; Intravascular ultrasound; Microvascular function; Plaque vulnerability; Thin cap fibroatheroma; Virtual histology

Indexed keywords

C REACTIVE PROTEIN; GLYCERYL TRINITRATE;

ACUTE CORONARY SYNDROME; ADULT; ARTERY CATHETER; ARTICLE; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; CORONARY FLOW RESERVE; CORONARY MICROVASCULAR DYSFUNCTION; DISEASE ASSOCIATION; FEMALE; FRACTIONAL FLOW RESERVE; HUMAN; HYPOTHESIS; INTRAVASCULAR ULTRASOUND; INVASIVE PROCEDURE; MAJOR CLINICAL STUDY; MALE; MICROANGIOPATHY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; ULTRASOUND SCANNER; VIRTUAL HISTOLOGY INTRAVASCULAR ULTRASOUND;

AGED; BIOLOGICAL MARKERS; BLOOD FLOW VELOCITY; C-REACTIVE PROTEIN; CORONARY ARTERY DISEASE; CORONARY CIRCULATION; CORONARY VESSELS; CROSS-SECTIONAL STUDIES; FEMALE; FIBROSIS; FRACTIONAL FLOW RESERVE, MYOCARDIAL; GEORGIA; HUMANS; INFLAMMATION MEDIATORS; MALE; MICROVESSELS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NECROSIS; PLAQUE, ATHEROSCLEROTIC; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; ULTRASONOGRAPHY, INTERVENTIONAL; UP-REGULATION;

EID: 84864778080     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.05.034     Document Type: Article

References (28)

1. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999, 340:115-126.
2. Cheruvu P.K., Finn A.V., Gardner C., et al. Frequency and distribution of thin-cap fibroatheroma and ruptured plaques in human coronary arteries: a pathologic study. J Am Coll Cardiol 2007, 50:940-949.
3. Finn A.V., Nakano M., Narula J., Kolodgie F.D., Virmani R. Concept of vulnerable/unstable plaque. Arterioscler Thromb Vasc Biol 2010, 30:1282-1292.
4. Kolodgie F.D., Burke A.P., Farb A., et al. The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes. Curr Opin Cardiol 2001, 16:285.
5. Moreno P.R., Bernardi V.H., Lopez-Cuellar J., et al. Macrophages, smooth muscle cells, and tissue factor in unstable angina. Implications for cell-mediated thrombogenicity in acute coronary syndromes. Circulation 1996, 94:3090-3097.
6. Moreno P.R. The high-risk thin-cap fibroatheroma: a new kid on the block. Circ Cardiovasc Interv 2009, 2:500-502.
7. Chamuleau S.A.J., Tio R.A., de Cock C.C., et al. Prognostic value of coronary blood flow velocity and myocardial perfusion in intermediate coronary narrowings and multivessel disease. J Am Coll Cardiol 2002, 39:852-858.
8. Pepine C.J., Anderson R.D., Sharaf B.L., et al. Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia: results from the National Heart, Lung and Blood Institute WISE (Women's Ischemia Syndrome Evaluation) study. J Am Coll Cardiol 2010, 55:2825-2832.
9. Sicari R., Rigo F., Cortigiani L., Gherardi S., Galderisi M., Picano E. Additive prognostic value of coronary flow reserve in patients with chest pain syndrome and normal or near-normal coronary arteries. Am J Cardiol 2009, 103:626-631.
10. Herrmann J. Peri-procedural myocardial injury: 2005 update. Eur Heart J 2005, 26:2493-2519.
11. Lerman A., Holmes D.R., Herrmann J., Gersh B.J. Microcirculatory dysfunction in ST-elevation myocardial infarction: cause, consequence, or both?. Eur Heart J 2007, 28:788-797.
12. Neri Serneri G.G., Boddi M., Modesti P.A., et al. Immunomediated and ischemia-independent inflammation of coronary microvessels in unstable angina. Circ Res 2003, 92:1359-1366.
13. Dhawan S.S., Eshtehardi P., McDaniel M.C., et al. The role of plasma aminothiols in the prediction of coronary microvascular dysfunction and plaque vulnerability. Atherosclerosis 2011, 219:266-272.
14. Samady H., Eshtehardi P., McDaniel M.C., et al. Coronary artery wall shear stress is associated with progression and transformation of atherosclerotic plaque and arterial remodeling in patients with coronary artery disease. Circulation 2011, 124:779-788.
15. Eshtehardi P., Luke J., McDaniel M.C., Samady H. Intravascular imaging tools in the cardiac catheterization laboratory: comprehensive assessment of anatomy and physiology. J Cardiovasc Transl Res 2011, 4:393-403.
16. Kern M.J., Samady H. Current concepts of integrated coronary physiology in the catheterization laboratory. J Am Coll Cardiol 2010, 55:173-185.
17. McDaniel M., Samady H. Use of coronary physiology in the catheterization laboratory to guide treatment in patients with coronary artery disease. Curr Treat Options Cardiovasc Med 2011, 13:35-45.
18. Garcia-Garcia H.M., Mintz G.S., Lerman A., et al. Tissue characterisation using intravascular radiofrequency data analysis: recommendations for acquisition, analysis, interpretation and reporting. EuroIntervention 2009, 5:177-189.
19. McDaniel M.C., Eshtehardi P., Sawaya F.J., Douglas J.S., Samady H. Contemporary clinical applications of coronary intravascular ultrasound. JACC Cardiovasc Interv 2011, 4:1155-1167.
20. Stone G.W., Maehara A., Lansky A.J., et al. A prospective natural-history study of coronary atherosclerosis. N Engl J Med 2011, 364:226-235.
21. Dhawan S.S., Avati Nanjundappa R.P., Branch J.R., et al. Shear stress and plaque development. Expet Rev Cardiovasc Ther 2010, 8:545-556.
22. Tomai F., Ribichini F., Ghini A.S., et al. Elevated C-reactive protein levels and coronary microvascular dysfunction in patients with coronary artery disease. Eur Heart J 2005, 26:2099-2105.
23. Philipp S., Böse D., Wijns W., et al. Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry. Eur Heart J 2010, 31:196-202.
24. Pundziute G., Schuijf J.D., van Velzen J.E., et al. Assessment with multi-slice computed tomography and gray-scale and virtual histology intravascular ultrasound of gender-specific differences in extent and composition of coronary atherosclerotic plaques in relation to age. Am J Cardiol 2010, 105:480-486.
25. Zheng M., Choi S.-Y., Tahk S.-J., et al. The relationship between volumetric plaque components and classical cardiovascular risk factors and the metabolic syndrome: a 3-vessel coronary artery virtual histology-intravascular ultrasound analysis. JACC Cardiovasc Interv 2011, 4:503-510.
26. Marso S.P., House J.A., Klauss V., Lerman A., Margolis P., Leon M.B. Diabetes mellitus is associated with plaque classified as thin cap fibroatheroma: an intravascular ultrasound study. Diab Vasc Dis Res 2010, 7:14-19.
27. Lindsey J.B., House J.A., Kennedy K.F., Marso S.P. Diabetes duration is associated with increased thin-cap fibroatheroma detected by intravascular ultrasound with virtual histology. Circ Cardiovasc Interv 2009, 2:543-548.
28. Marso S.P., Frutkin A.D., Menta S.K., et al. Intravascular ultrasound measures of coronary atherosclerosis are associated with the Framingham risk score: an analysis from a global IVUS registry. EuroIntervention 2009, 5:212-218.