Novel synthesis of trans-4,6-diaryl-5-nitropiperidin-2-ones via four-component reaction from substituted nitrostyrenes, aromatic aldehydes, dimethyl malonate, and formamide

Synlett

Volumn 23, Issue 15, 2012, Pages 2255-2260

  Zhou, Zhengquan ^a   Liu, Hui ^a   Sun, Qian ^a   Li, Yun ^a   Yang, Jing ^a   Liu, Juanjuan ^a   Yan, Peiyun ^a   Wang, Cunde ^a  

^a YANGZHOU UNIVERSITY   (China)

Author keywords

combinatorial chemistry; Michael addition; multicomponent reaction; piperidin 2 ones; piperidines

Indexed keywords

2 (1 ARYL 2 NITROETHYL)MALONIC ACID; 2 (3 AMINO 2 NITRO 1,3 DIARYLPROPYL)MALONIC ACID; 2 (3 FORMYLAMINO 2 NITRO 1,3 DIARYLPROPYL)MALONIC ACID; 4,6 DIARYL 5 NITROPIPERIDIN 2 ONE DERIVATIVE; ALDEHYDE; ARYLIMINE; CHEMICAL COMPOUND; DIMETHYL MALONIC ACID; FORMAMIDE; NITROSTYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; FOUR COMPONENT REACTION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SUBSTITUTION REACTION;

EID: 84864720617     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0032-1317044     Document Type: Article

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