Lab reports and cat scans: Can veterinary oncology guide our way to new treatments for human cancers?

Future Medicinal Chemistry

Volumn 4, Issue 11, 2012, Pages 1391-1394

  Airley, Rachel ^a  

^a UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

cancer; clinical trials; comparative oncology; synergy; tyrosine kinase inhibitor; veterinary

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLUORODEOXYGLUCOSE F 18; IMATINIB; MASITINIB; MATRIX METALLOPROTEINASE; PROSTAGLANDIN SYNTHASE; TOCERANIB;

ANIMAL DISEASE; BONE PAIN; BREAST CARCINOMA; BREAST METASTASIS; CANCER PATIENT; CHROMOSOME ABERRATION; CHRONIC MYELOID LEUKEMIA; COMPUTER ASSISTED TOMOGRAPHY; DISEASE MODEL; GASTROINTESTINAL STROMAL TUMOR; GENE MUTATION; HUMAN; LABORATORY TEST; LEUKEMIA; MASTOCYTOMA; MELANOMA; NEOPLASM; NONHUMAN; NOTE; OSTEOSARCOMA; PRIORITY JOURNAL; QUALITY OF LIFE; SARCOMA; VETERINARY MEDICINE;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CATS; DISEASE MODELS, ANIMAL; DOGS; FEMALE; HUMANS; INDOLES; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MAST-CELL SARCOMA; NEOPLASMS; PIPERAZINES; PROTEIN KINASE INHIBITORS; PYRIMIDINES; PYRROLES; THIAZOLES; TRANSCRIPTOME;

EID: 84864720114     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.12.81     Document Type: Note

References (21)

1. Martinez MN. Welcome to the animal pharmaceuticals special focus. Future Med. Chem. 3(7), 845-846 (2011).
2. Cardiff RD, Ward JM, Barthold SW. 'One medicine - one pathology': are veterinary and human pathology prepared? Lab. Invest. 88(1), 18-26 (2008).
3. Paoloni M, Davis S, Lana S et al. Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression. BMC Genomics 10, 625 (2009).
4. Breen M. Update on genomics in veterinary oncology. Top Companion Anim. Med. 24(3), 113-121 (2009).
5. Vail DM, MacEwen EG. Spontaneously occurring tumors of companion animals as models for human cancer. Cancer Invest. 18(8), 781-792 (2000).
6. Khanna C, Vail DM. Targeting the lung: preclinical and comparative evaluation of anticancer aerosols in dogs with naturally occurring cancers. Curr. Cancer Drug Targets 3(4), 265-273 (2003). (Pubitemid 36944260)
7. Pinho SS, Carvalho S, Cabral J, Reis CA, Gärtner F. Canine tumors: a spontaneous animal model of human carcinogenesis. Transl. Res. 159(3), 165-172 (2012).
8. Mueller F, Fuchs B, Kaser-Hotz B. Comparative biology of human and canine osteosarcoma. Anticancer Res. 27(1A), 155-164 (2007). (Pubitemid 46370589)
9. Rankin KS, Starkey M, Lunec J, Gerrand CH, Murphy S, Biswas S. Of dogs and men: comparative biology as a tool for the discovery of novel biomarkers and drug development targets in osteosarcoma. Pediatr. Blood Cancer 58(3), 327-333 (2012).
10. Brown DC, Boston R, Coyne JC, Farrar JT. A novel approach to the use of animals in studies of pain: validation of the canine brief pain inventory in canine bone cancer. Pain Med. 10(1), 133-142 (2009).
11. Queiroga FL, Raposo T, Carvalho MI, Prada J, Pires I. Canine mammary tumours as a model to study human breast cancer: most recent findings. In Vivo 25(3), 455-465 (2011).
12. Klopfleisch R, Lenze D, Hummel M, Gruber AD. The metastatic cascade is reflected in the transcriptome of metastatic canine mammary carcinomas. Vet. J. 190(2), 236-243 (2011).
13. Vail DM, Michels GM, Khanna C et al. Response evaluation criteria for peripheral nodal lymphoma in dogs (v1.0) - a Veterinary Cooperative Oncology Group (VCOG) consensus document. Vet. Comp. Oncol. 8(1), 28-37 (2010).
14. Leblanc AK, Miller AN, Galyon GD et al. Preliminary evaluation of serial 18FDG-PET/ CT to assess response to toceranib phosphate therapy in canine cancer. Vet. Radiol. Ultrasound 53(3), 348-357 (2012).
15. Croom KF, Perry CM. Imatinib mesylate: in the treatment of gastrointestinal stromal tumours. Drugs 63(5) 513-522; discussion 523-524 (2003).
16. Postow MA, Carvajal RD. Therapeutic Implications of KIT in Melanoma. Cancer J. 18(2), 137-141 (2012).
17. London CA. Tyrosine kinase inhibitors in veterinary medicine. Top. Companion Anim. Med. 24(3), 106-112 (2009).
18. Misdorp W. Mast cells and canine mast cell tumours. A review. Vet. Q. 26(4), 156-169 (2004). (Pubitemid 40109707)
19. Metcalfe DD. Regulation of normal and neoplastic human mast cell development in mastocytosis. Trans. Am. Clin. Climatol. Assoc. 116, 185-203; discussion 203-204 (2005).
20. Paoloni MC, Mazcko C, Fox E et al. Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs. PLoS ONE 5(6), e11013 (2010).
21. London CA, Bear MD, McCleese J et al. Phase I evaluation of STA-1474, a prodrug of the novel Hsp90 inhibitor ganetespib, in dogs with spontaneous cancer. PLoS ONE 6(11), e27018 (2011).