Effects of resveratrol on vascular endothelial growth factor expression in osteosarcoma cells and cell proliferation

Oncology Letters

Volumn 4, Issue 4, 2012, Pages 837-839

  Liu, Zhonghe ^a   Li, Yanlan ^b   Yang, Rui ^b  

^a THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIVERSITY   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

Esophageal cancer; Resveratrol; Vascular endothelial growth factor

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; RESVERATROL; VASCULOTROPIN;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL ASSAY; CELL PROLIFERATION; COLORIMETRY; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OSTEOSARCOMA; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84864698421     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.824     Document Type: Article

References (20)

1. Aggarwal BB, Bhardwj A, Aggarwal RS, Seeram NP, Shishodia S and Takada Y: Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res 24: 2783-2840, 2004.
2. Kundu JK, Chun KS, Kim SO and Surh YJ: Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets. Biofactors 21: 33-39, 2004.
3. Aziz MH, Kumar R and Ahmad N: Cancer chemoprevention by resveratrol in vitro and in vivo studies and the underlying mechanisms (review). Int J Oncol 23: 17-28, 2003.
4. Jiang H, Zhang U, Kuo J, et al: Resveratrol-induced apoptotic death in human U251 glioma cells. Mol Cancer Ther 4: 554-561, 2005.
5. Wang TT, Schoene NW, Kim EK and Kim YS: Pleiotropic effects of the sirtuin inhibitor sirtinol involves concentration-dependent modulation of multiple nuclear receptor-mediated pathways in androgen-responsive prostate cancer cell LNCaP. Mol Carcinog: Apr 11, 2012 (Epub ahead of print). doi: 10.1002/mc.21906
6. Juan ME, Alfaras I and Planas JM: Colorectal cancer chemopre-vention by trans-resveratrol. Pharmacol Res 65: 584-591, 2012.
7. Liu P, Wang X, Hu C and Hu T: Inhibition of proliferation and induction of apoptosis by trimethoxyl stilbene (TMS) in a lung cancer cell line. Asian Pac J Cancer Prev 12: 2263-2269, 2011.
8. Zhou JH, Cheng HY, Yu ZQ, et al: Resveratrol induces apoptosis in pancreatic cancer cells. Chin Med J (Engl) 124: 1695-1699, 2011.
9. Yu HB, Zhang HF, Zhang X, et al: Resveratrol inhibits VEGF expression of human hepatocellular carcinoma cells through a NF-kappa B-mediated mechanism. Hepatogastroenterology 57: 1241-1246, 2010.
10. Li Y, Bäckesjö CM, Haldosén LA and Lindgren U: Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells. Eur J Pharmacol 609: 13-18, 2009.
11. Dvorak HF, Brown LF, Detmar M and Dvorak AM: Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 146: 1029-1039, 1995.
12. Ranieri G, Patruno R, Ruggieri E, Montemurro S, Valerio P and Ribatti D: Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic. Curr Med Chem 13: 1845-1857, 2006.
13. Baker LC, Boult JK, Walker-Samuel S, et al: The HIF-pathway inhibitor NSC-13 4754 induces metabolic changes and anti-tumour activity while maintaining vascular function. Br J Cancer 106: 1638-1647, 2012.
14. Rieske P, Bartkowiak JK, Szadowska A M, Olborski B, Harezga-Bal B and Debiec-Rychter M: A comparative study of P53/MDM2 genes alterations and P53/MDM2 proteins immunoreactivity in soft-tissue sarcomas. J Exp Clin Cancer Res 18: 403-416, 1999.
15. Kim AL, Zhu Y, Zhu H, et al: Resveratrol inhibits proliferation of human epidermoid carcinoma A431 cells by modulating MEK1 and Ap-1 signalling pathways. Exp Dermatol 15: 538-546, 2006.
16. Kuwajerwala N, Cifuentes E, Gautam S, et al: Resveratrol induces prostate cancer cell entry into s phase and inhibits DNA synthesis. Cancer Res 62: 2488-2492, 2002.
17. Vyas S, Asmerem Y and De León DD: Resveratrol regulates insulin-like growth factor-II in breast cancer cells. Endocrinology 146: 4224-4233, 2005.
18. Golkar L, Ding XZ, Ujiki MB, et al: Resveratrol inhibits pancreatic cancer cell proliferation through transcriptional induction of macrophage inhibitory cytokine-1. J Surg Res 138: 163-169, 2007.
19. Gora-Tybor J, Blonski JZ and Robak T: Circulating vascular endothelial growth factor (VEGF) and its soluble receptors in patients with chronic lymphocytic leukemia. Eur Cytokine Netw 16: 41-46, 2005.
20. Hicklin DJ and Ellis LM: Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 23: 1011-1027, 2005.