Weakly charged cationic nanoparticles induce DNA bending and strand separation

Advanced Materials

Volumn 24, Issue 31, 2012, Pages 4261-4265

  Railsback, Justin G ^a   Singh, Abhishek ^a   Pearce, Ryan C ^a   McKnight, Timothy E ^b   Collazo, Ramõn ^a   Sitar, Zlatko ^a   Yingling, Yaroslava G ^a   Melechko, Anatoli V ^a  

^a North Carolina State University   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

cationic ligands; DNA compaction; DNA denaturing; DNA nanoparticle interactions; gold nanoparticles

Indexed keywords

BASE PAIRING; CATIONIC NANOPARTICLES; CHARGED LIGANDS; DNA BENDING; DNA COMPACTIONS; GOLD NANOPARTICLES; MOBILITY SHIFT; PHOSPHATE BACKBONE; STRAND SEPARATION; STRUCTURAL CHANGE; UV-VIS SPECTROPHOTOMETRY;

COMPACTION; ELECTROPHORESIS; LIGANDS; MOLECULAR DYNAMICS; NANOPARTICLES;

DNA;

CATION; DNA; GOLD; NANOPARTICLE;

ARTICLE; CHEMISTRY; CONFORMATION; DNA DENATURATION; MOLECULAR DYNAMICS; ULTRAVIOLET SPECTROPHOTOMETRY;

CATIONS; DNA; GOLD; MOLECULAR DYNAMICS SIMULATION; NANOPARTICLES; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84864685352     PISSN: 09359648     EISSN: 15214095     Source Type: Journal    
DOI: 10.1002/adma.201104891     Document Type: Article

References (27)

1. M. De, P. S. Ghosh, V. M. Rotello, Adv. Mater. 2008, 20, 4225.
2. P. S. Ghosh, C. K. Kim, G. Han, N. S. Forbes, V. M. Rotello, ACS Nano 2008, 2, 2213.
3. D. Li, G. P. Li, W. W. Guo, P. C. Li, E. K. Wang, J. Wang, Biomaterials 2008, 29, 2776.
4. G. Han, P. Ghosh, M. De, V. M. Rotello, Nanobiotechnology 2007, 3, 40.
5. M. Homberger, U. Simon, Philos. Trans. R. Soc A 2010, 368, 1405.
6. A. Kumar, M. Pattarkine, M. Bhadbhade, A. B. Mandale, K. N. Ganesh, S. S. Datar, C. V. Dharmadhikari, M. Sastry, Adv. Mater. 2001, 13, 341.
7. M. Emanuel, N. H. Radja, A. Henriksson, H. Schiessel, Phys. Biol. 2009, 6, 025008.
8. H. Schiessel, J. Phys. Condens. Matter 2003, 15, R699.
9. T. Akitaya, A. Seno, T. Nakai, N. Hazemoto, S. Murata, K. Yoshikawa, Biomacromolecules 2007, 8, 273.
10. C. F. Ke, S. Hou, H. Y. Zhang, Y. Liu, K. Yang, X. Z. Feng, Chem. Commun. 2007, 3374.
11. C. J. Su, C. Y. Chen, H. L. Chen, V. A. Ivanov, Future Trends Soft Mater. Res. Adv. Light Sources 2011, 272.
12. B. Nandy, P. K. Maiti, J. Phys. Chem. B 2011, 115, 217.
13. G. Han, C. T. Martin, V. M. Rotello, Chem. Biol. Drug Des. 2006, 67, 78.
14. C. M. Goodman, N. S. Chari, G. Han, R. Hong, P. Ghosh, V. M. Rotello, Chem. Biol. Drug. Des. 2006, 67, 297.
15. A. Estevez-Torres, D. Baigl, Soft Matter 2011, 7, 6746.
16. D. Zanchet, C. M. Micheel, W. J. Parak, D. Gerion, A. P. Alivisatos, Nano Lett. 2001, 1, 32.
17. D. B. Peckys, N. de Jonge, M. L. Simpson, T. E. McKnight, Nanotechnology 2008, 19.
18. K. Hamad-Schifferli, J. J. Schwartz, A. T. Santos, S. G. Zhang, J. M. Jacobson, Nature 2002, 415, 152.
19. I. Tinoco, J. Am. Chem. Soc. 1960, 82, 4785.
20. M. M. Bradford, Anal. Biochem. 1976, 72, 248.
21. X. Cai, P. J. Gray Jr., D. D. Von Hoff, Cancer Treat. Rev. 2009, 35, 437.
22. D. H. Turner, N. Sugimoto, S. M. Freier, Annu. Rev. Biophys. Biophys. Chem. 1988, 17, 167.
23. D. A. Case, T. A. Darden, T. E. Cheatham III, C. L. Simmerling, J. Wang, R. E. Duke, R. Luo, M. Crowley, R. C. Walker, W. Zhang, K. M. Merz, B. Wang, S. Hayik, A. Roitberg, G. Seabra, I. Kolossváry, K. F. Wong, F. Paesani, J. Vanicek, X. Wu, S. R. Brozell, T. Steinbrecher, H. Gohlke, L. Yang, C. Tan, J. Mongan, V. Hornak, G. Cui, D. H. Mathews, M. G. Seetin, C. Sagui, V. Babin, P. A. Kollman, AMBER11, University of California, San Francisco 2010.
24. Y. Duan, C. Wu, S. Chowdhury, M. C. Lee, G. M. Xiong, W. Zhang, R. Yang, P. Cieplak, R. Luo, T. Lee, J. Caldwell, J. M. Wang, P. Kollman, J. Comput. Chem. 2003, 24, 1999.
25. C. A. Fields-Zinna, R. Sardar, C. A. Beasley, R. W. Murray, J. Am. Chem. Soc. 2009, 131, 16266.
26. A. Singh, S. Snyder, L. Lee, A. P. R. Johnston, F. Caruso, Y. G. Yingling, Langmuir 2010, 26, 17339.
27. A. Singh, L. Sethaphong, Y. G. Yingling, Biophys. J. 2011, 101, 727.