Aqueous extract of Vitex trifolia L. (Labiatae) inhibits LPS-dependent regulation of inflammatory mediators in RAW 264.7 macrophages through inhibition of Nuclear Factor kappa B translocation and expression

Journal of Ethnopharmacology

Volumn 143, Issue 1, 2012, Pages 24-32

  Matsui, Mariko ^a   Adib Conquy, Minou ^b   Coste, Agnès ^c   Kumar Roiné, Shilpa ^c   Pipy, Bernard ^c   Laurent, Dominique ^c   Pauillac, Serge ^b  

^a Institut Pasteur de Nouvelle Caledonie Noumea   (New Caledonia)

^b INSTITUT PASTEUR   (France)

^c Hôpital Purpan   (French Polynesia)

Author keywords

Anti inflammatory activity; Chemokines; COX 2; Cytokines; Lipopolysaccharide; Nuclear factor kappa B; Vitex trifolia

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; NUCLEAR FACTOR; PLANT EXTRACT; UNCLASSIFIED DRUG; VITEX TRIFOLIA EXTRACT;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; IN VITRO STUDY; INCUBATION TIME; INFLAMMATION; INHIBITION KINETICS; MACROPHAGE; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT LEAF; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STRESS; TOXICITY; UNINDEXED SEQUENCE; VITEX TRIFOLIA;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL TRANSPORT; CHEMOKINE CCL3; CHEMOKINE CXCL10; CHEMOKINES; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; GENE EXPRESSION; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; PHYTOTHERAPY; PLANT EXTRACTS; RNA, MESSENGER; TRANSCRIPTION FACTOR RELA; VITEX;

LAMIACEAE; VITEX TRIFOLIA;

EID: 84864666660     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.05.043     Document Type: Article

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