Isolated tramadol overdose associated with brugada ECG pattern

PACE - Pacing and Clinical Electrophysiology

Volumn 35, Issue 8, 2012, Pages

  Cole, Jon B ^a,b   Sattiraju, Srinivasan ^c   Bilden, Elisabeth F ^a   Asinger, Richard W ^b   Bertog, Stefan C ^d  

^a Hennepin Regional Poison Center   (United States)

^b HENNEPIN COUNTY MEDICAL CENTER   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

brugada; ECG pattern; sodium channel blockers; tramadol

Indexed keywords

NALOXONE; SODIUM CHANNEL; TRAMADOL;

ADULT; ARTIFICIAL VENTILATION; BLOOD EXAMINATION; BRUGADA SYNDROME; CASE REPORT; CLINICAL ASSESSMENT; ELECTROCARDIOGRAPHY; HOSPITAL DISCHARGE; HUMAN; HYPOVENTILATION; INTOXICATION; MALE; MENTAL HEALTH; PHYSICAL EXAMINATION; REVIEW; ST SEGMENT ELEVATION; SUICIDE;

ANALGESICS, OPIOID; BRUGADA SYNDROME; HUMANS; MALE; MIDDLE AGED; NALOXONE; NARCOTIC ANTAGONISTS; PRESCRIPTION DRUG MISUSE; SODIUM CHANNEL BLOCKERS; TRAMADOL; TREATMENT OUTCOME;

EID: 84864664201     PISSN: 01478389     EISSN: 15408159     Source Type: Journal    
DOI: 10.1111/j.1540-8159.2010.02924.x     Document Type: Review

References (16)

1. Stork CM, Redd JT, Fine K, Hoffman RS,. Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate-a case report. J Toxicol Clin Toxicol 1995; 33: 179-183.
2. Akhtar M, Goldschlager NF,. Brugada electrocardiographic pattern due to tricyclic antidepressant overdose. J Electrocardiol 2006; 39: 336-339.
3. Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D, Gussak I, et al,. Brugada syndrome: Report of the Second Consensus Conference: Endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. Circulation 2005; 111: 659-670.
4. Gussak I, Antzelevitch C, Bjerregaard P, Towbin JA, Chaitman BR,. The Brugada syndrome: Clinical, electrophysiologic and genetic aspects. J Am Coll Cardiol 1999; 33: 5-15.
5. Haeseler G, Foadi N, Ahrens J, Dengler R, Hecker H, Leuwer M,. Tramadol, fentanyl and sufentanil but not morphine block voltage-operated sodium channels. Pain 2006; 126: 234-244.
6. Katsuki R, Fujita T, Koga A, Liu T, Nakatsuka T, Nakashima M, Kumamoto E,. Tramadol, but not its major metabolite (mono-O-desmethyl tramadol) depresses compound action potentials in frog sciatic nerves. Br J Pharmacol 2006; 149: 319-327.
7. Altunkaya H, Ozer Y, Kargi E, Ozkocak I, Hosnuter M, Demirel CB, Babuccu O,. The postoperative analgesic effect of Tramadol when used as subcutaneous local anesthetic. Anesth Analg 2004; 99: 1461-1464.
8. Hudson CJ, Whitner TE, Rinaldi MJ, Littman L,. Brugada electrocardiographic pattern elicited by inadvertent flecainide overdose. Pacing Clin Electrophysiol 2004; 27: 1311-1313.
9. Ott P, Freund NS,. Brugada-pattern ekg in a febrile patient. J Emerg Med 2007; 33: 281-282.
10. Kovacic JC, Kuchar DL,. Brugada pattern electrocardiographic changes associated with profound electrolyte disturbance. Pacing Clin Electrophysiol 2004; 27: 1020-1023.
11. Mok NS, Tong CK, Yuen HC,. Concomitant-acquired Long QT and Brugada syndromes associated with indapamide-induced hypokalemia and hyponatremia. Pacing Clin Electrophysiol 2008; 31: 772-775.
12. Tamene A, Sattiraju S, Wang K, Benditt DG,. Brugada-like electrocardiography pattern induced by severe hyponatraemia. Europace 2010; 12: 905-907.
13. Bebarta VS, Summers S,. Brugada. Electrocardiographic pattern induced by cocaine toxicity. Ann Emerg Med 2007; 49: 827-829.
14. Al Aloul B, Adabag AS, Houghland MA, Tholakanahalli V,. Brugada pattern electrocardiogram associated with supratherapeutic phenytoin levels and the risk of sudden death. Pacing Clin Electrophysiol 2007; 30: 713-715.
15. Wang K, Asinger RW, Marriott JHL,. ST Segment elevation in conditions other than acute myocardial infarction. N Engl J Med 2003; 349: 2128-2135.
16. Shadnia S, Soltaninejad K, Heydari K, Sasanian G, Abdollahi M,. Tramadol intoxication: A review of 114 cases. Hum Ex Toxicol 2008; 27: 201-205.