Evidence that 3-hydroxyisobutyric acid inhibits key enzymes of energy metabolism in cerebral cortex of young rats

International Journal of Developmental Neuroscience

Volumn 26, Issue 3-4, 2008, Pages 293-299

  Viegas, Carolina Maso ^a   da Costa Ferreira, Gustavo ^a   Schuck, Patrícia Fernanda ^a   Tonin, Anelise Miotti ^a   Zanatta, Ângela ^a   de Souza Wyse, Angela Terezinha ^a   Dutra Filho, Carlos Severo ^a   Wannmacher, Clóvis Milton Duval ^a   Wajner, Moacir ^a,b,c  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

3 Hydroxyisobutyric acid; 3 Hydroxyisobutyric aciduria; Cerebral cortex; Creatine kinase; Energy metabolism; K+ ATPase; Na+; Respiratory chain

Indexed keywords

3 HYDROXY 2 METHYLPROPIONIC ACID; ADENOSINE TRIPHOSPHATASE (POTASSIUM); ALPHA TOCOPHEROL; CATALASE; CREATINE KINASE; GLUTAMIC ACID; GLUTATHIONE; HYDROGEN PEROXIDE; LACTIC ACID; MALIC ACID; PEROXY RADICAL; SODIUM ION; SUCCINIC ACID; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN METABOLISM; CELL RESPIRATION; CONTROLLED STUDY; ELECTRON TRANSPORT; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; MITOCHONDRIAL RESPIRATION; NERVE DEGENERATION; NEUROTRANSMISSION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT;

3-HYDROXYBUTYRIC ACID; AGING; ANIMALS; ANTIOXIDANTS; BRAIN CHEMISTRY; BRAIN DISEASES, METABOLIC, INBORN; CELL MEMBRANE; CELL RESPIRATION; CEREBRAL CORTEX; CREATINE KINASE; ELECTRON TRANSPORT COMPLEX I; ENERGY METABOLISM; MITOCHONDRIA; OXYGEN CONSUMPTION; RATS; RATS, WISTAR; SODIUM-POTASSIUM-EXCHANGING ATPASE; SUBCELLULAR FRACTIONS; SYNAPTIC MEMBRANES;

RATTUS;

EID: 41649087110     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2008.01.007     Document Type: Article

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