Dynamic changes in MELD score not only predict survival on the waiting list but also overall survival after liver transplantation

Transplant International

Volumn 25, Issue 9, 2012, Pages 935-940

  Györi, Georg P ^a   Silberhumer, Gerd R ^a   Zehetmayer, Sonja ^a   Kern, Barbara ^a   Hetz, Hubert ^a   Soliman, Thomas ^a   Steininger, Rudolf ^a   Mühlbacher, Ferdinand ^a   Berlakovich, Gabriela A ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

liver transplantation; MELD; post transplant survival

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL DISEASE; HOSPITAL ADMISSION; HUMAN; KIDNEY FAILURE; LIVER FAILURE; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MELD SCORE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; POST TREATMENT SURVIVAL; POSTOPERATIVE INFECTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; RETROSPECTIVE STUDY; RISK ASSESSMENT; SCORING SYSTEM; SURGICAL INFECTION; SURGICAL MORTALITY; SURVIVAL PREDICTION;

ADULT; AGED; ALGORITHMS; COHORT STUDIES; FEMALE; HUMANS; LIVER FAILURE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; MODELS, STATISTICAL; MULTIVARIATE ANALYSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME; WAITING LISTS;

EID: 84864653841     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2012.01519.x     Document Type: Article

References (28)

1. Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC,. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology 2000; 31: 864.
2. Brown RS, Jr., Kumar KS, Russo MW, et al. Model for end-stage liver disease and Child-Turcotte-Pugh score as predictors of pretransplantation disease severity, posttransplantation outcome, and resource utilization in United Network for Organ Sharing status 2A patients. Liver Transpl 2002; 8: 278.
3. Kamath PS, Wiesner RH, Malinchoc M, et al. A model to predict survival in patients with end-stage liver disease. Hepatology 2001; 33: 464.
4. Edwards EB, Harper AM,. Application of a continuous disease severity score to the OPTN liver waiting list. Clin Transpl 2001: 19.
5. Freeman RB, Jr., Edwards EB,. Liver transplant waiting time does not correlate with waiting list mortality: implications for liver allocation policy. Liver Transpl 2000; 6: 543.
6. Wiesner R, Edwards E, Freeman R, et al. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology 2003; 124: 91.
7. Wiesner RH, McDiarmid SV, Kamath PS, et al. MELD and PELD: application of survival models to liver allocation. Liver Transpl 2001; 7: 567.
8. Saab S, Wang V, Ibrahim AB, et al. MELD score predicts 1-year patient survival post-orthotopic liver transplantation. Liver Transpl 2003; 9: 473.
9. Onaca NN, Levy MF, Netto GJ, et al. Pretransplant MELD score as a predictor of outcome after liver transplantation for chronic hepatitis C. Am J Transplant 2003; 3: 626.
10. Desai NM, Mange KC, Crawford MD, et al. Predicting outcome after liver transplantation: utility of the model for end-stage liver disease and a newly derived discrimination function. Transplantation 2004; 77: 99.
11. Silberhumer GR, Hetz H, Rasoul-Rockenschaub S, et al. Is MELD score sufficient to predict not only death on waiting list, but also post-transplant survival? Transpl Int 2006; 19: 275.
12. Hayashi PH, Forman L, Steinberg T, et al. Model for end-stage liver disease score does not predict patient or graft survival in living donor liver transplant recipients. Liver Transpl 2003; 9: 737.
13. Oberkofler CE, Dutkowski P, Stocker R, et al. Model of end stage liver disease (MELD) score greater than 23 predicts length of stay in the ICU but not mortality in liver transplant recipients. Crit Care 2010; 14: R117.
14. Merion RM, Wolfe RA, Dykstra DM, Leichtman AB, Gillespie B, Held PJ,. Longitudinal assessment of mortality risk among candidates for liver transplantation. Liver Transpl 2003; 9: 12.
15. Bambha K, Kim WR, Kremers WK, et al. Predicting survival among patients listed for liver transplantation: an assessment of serial MELD measurements. Am J Transplant 2004; 4: 1798.
16. Northup PG, Berg CL,. Preoperative delta-MELD score does not independently predict mortality after liver transplantation. Am J Transplant 2004; 4: 1643.
17. Foxton MR, Kendrick S, Sizer E, et al. Change in model for end-stage liver disease score on the transplant waiting list predicts survival in patients undergoing liver transplantation. Transpl Int 2006; 19: 988.
18. Silberhumer GR, Pokorny H, Hetz H, et al. Combination of extended donor criteria and changes in the model for end-stage liver disease score predict patient survival and primary dysfunction in liver transplantation: a retrospective analysis. Transplantation 2007; 83: 588.
19. Bernardi M, Gitto S, Biselli M,. The MELD score in patients awaiting liver transplant: strengths and weaknesses. J Hepatol 2011; 54: 1297.
20. Weismuller TJ, Fikatas P, Schmidt J, et al. Multicentric evaluation of model for end-stage liver disease-based allocation and survival after liver transplantation in Germany-limitations of the 'sickest first'-concept. Transpl Int. 2011; 24: 91.
21. Metselaar HJ, Lerut J, Kazemier G,. The true merits of liver allocation according to MELD scores: survival after transplantation tells only one side of the story. Transpl Int 2011; 24: 132.
22. Schaubel DE, Guidinger MK, Biggins SW, et al. Survival benefit-based deceased-donor liver allocation. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. [Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S.]. 2009; 9: 970.
23. Freeman RB, Wiesner RH, Edwards E, Harper A, Merion R, Wolfe R,. Results of the first year of the new liver allocation plan. Liver Transpl 2004; 10: 7.
24. Kim WR, Biggins SW, Kremers WK, et al. Hyponatremia and mortality among patients on the liver-transplant waiting list. N Engl J Med. [Comparative Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Validation Studies]. 2008; 359: 1018.
25. Onaca NN, Levy MF, Sanchez EQ, et al. A correlation between the pretransplantation MELD score and mortality in the first two years after liver transplantation. Liver Transpl 2003; 9: 117.
26. Feng S, Goodrich NP, Bragg-Gresham JL, et al. Characteristics associated with liver graft failure: the concept of a donor risk index. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. [Research Support, U.S. Gov't, P.H.S.]. 2006; 6: 783.
27. Rana A, Hardy MA, Halazun KJ, et al. Survival outcomes following liver transplantation (SOFT) score: a novel method to predict patient survival following liver transplantation. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. [Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S.]. 2008; 8: 2537.
28. Halldorson JB, Bakthavatsalam R, Fix O, Reyes JD, Perkins JD,. D-MELD, a simple predictor of post liver transplant mortality for optimization of donor/recipient matching. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. [Research Support, U.S. Gov't, P.H.S.]. 2009; 9: 318.