Short-term levosimendan treatment protects rat testes against oxidative stress

Brazilian Journal of Medical and Biological Research

Volumn 45, Issue 8, 2012, Pages 716-720

  Yuksel, M B ^a   Kavak, S ^b   Gecit, I ^b   Basel, H ^c   Gumrukcuoglu H A ^b   Demir, H ^b   Meral, I ^b  

^a State Hospital of Mus   (Turkey)

^b YUZUNCU YIL UNIVERSITY   (Turkey)

^c University Hospital   (Turkey)

Author keywords

GSH Px; Levosimendan; MDA; Oxidative stress; Rat testes; Reactive oxygen species; SOD

Indexed keywords

CADMIUM; CARBONATE DEHYDRATASE; CATALASE; COBALT; COPPER; GLUTATHIONE PEROXIDASE; IRON; LEAD; LEVOSIMENDAN; MAGNESIUM; MALONALDEHYDE; MANGANESE; SUPEROXIDE DISMUTASE; ZINC;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; SHORT COURSE THERAPY; TESTIS; TISSUE LEVEL;

ANIMALIA; RATTUS;

EID: 84864650451     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2012007500075     Document Type: Article

References (40)

1. Adams JG Jr, Dhar A, Shukla SD, Silver D. Effect of pentoxifylline on tissue injury and platelet-activating factor production during ischemia-reperfusion injury. J Vasc Surg 1995; 21: 742-748.
2. Troyer-Caudle J. Reperfusion injury. J Vasc Nurs 1993; 11: 76-79.
3. Sucu N, Unlu A, Tamer L, Aytacoglu B, Coskun B, Bilgin R, et al. Effects of trimetazidine on tissue damage in kidney after hindlimb ischemia-reperfusion. Pharmacol Res 2002; 46: 345-349.
4. Neary P, Redmond HP. Ischemia-reperfusion injury and the systemic inflammatory response syndrome. Ischemiareperfusion injury. London: Blackwell Science; 1999.
5. Özer AB, Kaman D. Effects of epigallocatechin 3-gallate in rat cardiac tissue on oxidant and antioxidant system exposed to sevoflurane anesthesia. Fýrat Týp Dergisi 2007; 12: 93-96.
6. Free MJ, Schluntz GA, Jaffe RA. Respiratory gas tensions in tissues and fluids of the male rat reproductive tract. Biol Reprod 1976; 14: 481-488.
7. Peltola V, Mantyla E, Huhtaniemi I, Ahotupa M. Lipid peroxidation and antioxidant enzyme activities in the rat testis after cigarette smoke inhalation or administration of polychlorinated biphenyls or polychlorinated naphthalenes. J Androl 1994; 15: 353-361.
8. Quinn PG, Payne AH. Oxygen-mediated damage of microsomal cytochrome P-450 enzymes in cultured Leydig cells. Role in steroidogenic desensitization. J Biol Chem 1984; 259: 4130-4135.
9. Chen H, Liu J, Luo L, Baig MU, Kim JM, Zirkin BR. Vitamin E, aging and Leydig cell steroidogenesis. Exp Gerontol 2005; 40: 728-736.
10. Follath F, Cleland JG, Just H, Papp JG, Scholz H, Peuhkurinen K, et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial. Lancet 2002; 360: 196-202.
11. Parissis JT, Adamopoulos S, Antoniades C, Kostakis G, Rigas A, Kyrzopoulos S, et al. Effects of levosimendan on circulating pro-inflammatory cytokines and soluble apoptosis mediators in patients with decompensated advanced heart failure. Am J Cardiol 2004; 93: 1309-1312.
12. Kavak S, Ayaz L, Emre M, Inal T, Tamer L, Gunay I. The effects of rosiglitazone on oxidative stress and lipid profile in left ventricular muscles of diabetic rats. Cell Biochem Funct 2008; 26: 478-485.
13. Kavak S, Ayaz L, Emre M. Effects of insulin on oxidative stress and free fatty acid level in left ventricular muscles of diabetic rats. Asian J Chem 2009; 21: 5677-5684.
14. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967; 70: 158-169.
15. Aebi H. Catalase in vitro. In: Bergmayer HU (Editor), Methods of enzymatic analysis. New York: Academic Press Inc.; 1974. p 673-677.
16. Durak I, Canbolat O, Kavutcu M, Ozturk HS, Yurtarslani Z. Activities of total, cytoplasmic, and mitochondrial superoxide dismutase enzymes in sera and pleural fluids from patients with lung cancer. J Clin Lab Anal 1996; 10: 17-20.
17. Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 1968; 25: 192-205.
18. Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121-126.
19. Rickli EE, Ghazanfar SA, Gibbons BH, Edsall JT. Carbonic anhydrases from human erythrocytes. Preparation and properties of two enzymes. J Biol Chem 1964; 239: 1065-1078.
20. Bush VJ, Moyer TP, Batts KP, Parisi JE. Essential and toxic element concentrations in fresh and formalin-fixed human autopsy tissues. Clin Chem 1995; 41: 284-294.
21. Yaman M, Akdeniz I. Sensitivity enhancement in flame atomic absorption spectrometry for determination of copper in human thyroid tissues. Anal Sci 2004; 20: 1363-1366.
22. Kaur P, Kaur G, Bansal MP. Tertiary-butyl hydroperoxide induced oxidative stress and male reproductive activity in mice: role of transcription factor NF-kappaB and testicular antioxidant enzymes. Reprod Toxicol 2006; 22: 479-484.
23. Kang YJ, Chen Y, Epstein PN. Suppression of doxorubicin cardiotoxicity by overexpression of catalase in the heart of transgenic mice. J Biol Chem 1996; 271: 12610-12616.
24. Nordberg J, Arner ES. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic Biol Med 2001; 31: 1287-1312.
25. Zini A, Schlegel PN. Catalase mRNA expression in the male rat reproductive tract. J Androl 1996; 17: 473-480.
26. Peltola V, Huhtaniemi I, Ahotupa M. Antioxidant enzyme activity in the maturing rat testis. J Androl 1992; 13: 450-455.
27. Yazar E, Konyalioglu S, Col R, Osman Birdane Y, Levent B, Elmas M. Effects of vitamin E and prednisolone on some oxidative stress markers in endotoxemic rabbits. Rev Méd Vét 2004; 155: 538-542.
28. Oteiza PL, Olin KL, Fraga CG, Keen CL. Oxidant defense systems in testes from zinc-deficient rats. Proc Soc Exp Biol Med 1996; 213: 85-91.
29. Celino FT, Yamaguchi S, Miura C, Ohta T, Tozawa Y, Iwai T, et al. Tolerance of spermatogonia to oxidative stress is due to high levels of Zn and Cu/Zn superoxide dismutase. PLoS One 2011; 6: e16938.
30. Merker HJ, Gunther T, Hollriegl V, Vormann J, Schumann K. Lipid peroxidation and morphology of rat testis in magnesium deficiency. Andrologia 1996; 28: 43-51.
31. Ikeda M, Kodama H, Fukuda J, Shimizu Y, Murata M, Kumagai J, et al. Role of radical oxygen species in rat testicular germ cell apoptosis induced by heat stress. Biol Reprod 1999; 61: 393-399.
32. Smith R, Kaune H, Parodi D, Madariaga M, Morales I, Rios R, et al. [Extent of sperm DNA damage in spermatozoa from men examined for infertility. Relationship with oxidative stress]. Rev Med Chil 2007; 135: 279-286.
33. Unsal A, Eroglu M, Avci A, Cimentepe E, Guven C, Derya BM, et al. Protective role of natural antioxidant supplementation on testicular tissue after testicular torsion and detorsion. Scand J Urol Nephrol 2006; 40: 17-22.
34. Uguralp S, Usta U, Mizrak B. Resveratrol may reduce apoptosis of rat testicular germ cells after experimental testicular torsion. Eur J Pediatr Surg 2005; 15: 333-336.
35. Dokmeci D, Inan M, Basaran UN, Yalcin O, Aydogdu N, Turan FN, et al. Protective effect of L-carnitine on testicular ischaemia-reperfusion injury in rats. Cell Biochem Funct 2007; 25: 611-618.
36. Atik E, Gorur S, Kiper AN. The effect of caffeic acid phenethyl ester (CAPE) on histopathological changes in testicular ischemia-reperfusion injury. Pharmacol Res 2006; 54: 293-297.
37. Agarwal A, Prabakaran S, Allamaneni SS. Relationship between oxidative stress, varicocele and infertility: a metaanalysis. Reprod Biomed Online 2006; 12: 630-633.
38. Agbaje IM, Rogers DA, McVicar CM, McClure N, Atkinson AB, Mallidis C, et al. Insulin dependent diabetes mellitus: implications for male reproductive function. Hum Reprod 2007; 22: 1871-1877.
39. Cay A, Alver A, Kucuk M, Isik O, Eminagaoglu MS, Karahan SC, et al. The effects of N-acetylcysteine on antioxidant enzyme activities in experimental testicular torsion. J Surg Res 2006; 131: 199-203.
40. Liu ZM, Zheng XM, Yang ZW, Li SW. [Protective effect of pentoxifylline on spermatogenesis following testicular torsion/ detorsion in rats]. Zhonghua Nan Ke Xue 2006; 12: 323-5, 329.