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Volumn 849, Issue , 2012, Pages 347-359

Cell-to-cell transmission of α-synuclein aggregates

Author keywords

Synuclein; Lewy body disease; Neurodegeneration; Neurons; Parkinson's disease; Propagation; Protein dissemination

Indexed keywords

ALPHA SYNUCLEIN; LENTIVIRUS VECTOR;

EID: 84864629186     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-551-0_23     Document Type: Article
Times cited : (45)

References (34)
  • 1
    • 7044238416 scopus 로고    scopus 로고
    • Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
    • Forman, M.S., Trojanowski, J.Q. and Lee, V.M. (2004). Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 10 , 1055-63
    • (2004) Nat Med , vol.10 , pp. 1055-1063
    • Forman, M.S.1    Trojanowski, J.Q.2    Lee, V.M.3
  • 2
    • 77955943958 scopus 로고    scopus 로고
    • Tau cleavage and tau aggregation in neurodegenerative disease
    • Hanger, D.P. and Wray, S. (2010) Tau cleavage and tau aggregation in neurodegenerative disease. Biochem Soc Trans 38 , 1016-20
    • (2010) Biochem Soc Trans , vol.38 , pp. 1016-1020
    • Hanger, D.P.1    Wray, S.2
  • 3
    • 84880187014 scopus 로고    scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis: An update and reappraisal
    • Hardy, J. (2006). Alzheimer's disease: the amyloid cascade hypothesis: an update and reappraisal. J Alzheimers Dis 9 , 151-3
    • (2006) J Alzheimers Dis , vol.9 , pp. 151-153
    • Hardy, J.1
  • 4
    • 0028267440 scopus 로고
    • Normal and abnormal biology of the beta-amyloid precursor protein
    • Selkoe, D.J. (1994). Normal and abnormal biology of the beta-amyloid precursor protein. Annu Rev Neurosci 17 , 489-517
    • (1994) Annu Rev Neurosci , vol.17 , pp. 489-517
    • Selkoe, D.J.1
  • 5
    • 0035409575 scopus 로고    scopus 로고
    • Alpha-synuclein and neurodegenerative diseases
    • Goedert, M. (2001). Alpha-synuclein and neurodegenerative diseases. Nat Rev Neurosci 2 , 492-501
    • (2001) Nat Rev Neurosci , vol.2 , pp. 492-501
    • Goedert, M.1
  • 6
    • 0035031135 scopus 로고    scopus 로고
    • Parkinson's disease and other alpha-synucleinopathies
    • Goedert, M. (2001). Parkinson's disease and other alpha- synucleinopathies. Clin Chem Lab Med 39 , 308-12
    • (2001) Clin Chem Lab Med , vol.39 , pp. 308-312
    • Goedert, M.1
  • 7
    • 3142640821 scopus 로고    scopus 로고
    • Huntington's disease: New paths to pathogenesis
    • Ross, C.A. (2004). Huntington's disease: new paths to pathogenesis. Cell 118 , 4-7
    • (2004) Cell , vol.118 , pp. 4-7
    • Ross, C.A.1
  • 8
    • 0036669881 scopus 로고    scopus 로고
    • Amyloid-beta oligomers: Their production, toxicity and therapeutic inhibition
    • Walsh, D.M., Klyubin, I., Fadeeva, J.V., Rowan, M.J. and Selkoe, D.J. (2002). Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition. Biochem Soc Trans 30 , 552-7
    • (2002) Biochem Soc Trans , vol.30 , pp. 552-557
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Rowan, M.J.4    Selkoe, D.J.5
  • 9
    • 2542427690 scopus 로고    scopus 로고
    • Oligomers on the brain: The emerging role of soluble protein aggregates in neurodegeneration
    • Walsh, D.M. and Selkoe, D.J. (2004). Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration. Protein Pept Lett 11 , 213-28
    • (2004) Protein Pept Lett , vol.11 , pp. 213-228
    • Walsh, D.M.1    Selkoe, D.J.2
  • 10
    • 34248190279 scopus 로고    scopus 로고
    • A beta oligomers-A decade of discovery
    • Walsh, D.M. and Selkoe, D.J. (2007). A beta oligomers-A decade of discovery. J Neurochem 101 , 1172-84
    • (2007) J Neurochem , vol.101 , pp. 1172-1184
    • Walsh, D.M.1    Selkoe, D.J.2
  • 11
    • 0038038389 scopus 로고    scopus 로고
    • Soluble oligomers for the diagnosis of neurodegenerative diseases
    • El-Agnaf, O.M., Walsh, D.M. and Allsop, D. (2003). Soluble oligomers for the diagnosis of neurodegenerative diseases. Lancet Neurol 2 , 461-2
    • (2003) Lancet Neurol , vol.2 , pp. 461-462
    • El-Agnaf, O.M.1    Walsh, D.M.2    Allsop, D.3
  • 13
    • 77949881747 scopus 로고    scopus 로고
    • Review: Autophagy and neurodegeneration: Survival at a cost
    • Cherra, S.J., 3 rd, Dagda, R.K. and Chu, C.T. (2010). Review: autophagy and neurodegeneration: survival at a cost? Neuropathol Appl Neurobiol 36 , 125-32
    • (2010) Neuropathol Appl Neurobiol , vol.36 , pp. 125-132
    • Cherra, S.J.1    Dagda, R.K.2    Chu, C.T.3
  • 14
    • 77949504405 scopus 로고    scopus 로고
    • Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alphasynucleinopathy
    • Crews, L. et al. (2010). Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alphasynucleinopathy. PLoS One 5, e9313
    • (2010) PLoS One , vol.5
    • Crews, L.1
  • 15
    • 77953463398 scopus 로고    scopus 로고
    • Protein degradation, aggregation, and misfolding
    • Cuervo, A.M., Wong, E.S. and Martinez-Vicente, M. (2010). Protein degradation, aggregation, and misfolding. Mov Disord 25 Suppl 1 , S49-54
    • (2010) Mov Disord , vol.25 , Issue.SUPPL. 1
    • Cuervo, A.M.1    Wong, E.S.2    Martinez-Vicente, M.3
  • 16
    • 77949902558 scopus 로고    scopus 로고
    • Collective roles of molecular chaperones in protein degradation pathways associated with neurodegenerative diseases
    • Luo, G.R. and Le, W.D. (2010). Collective roles of molecular chaperones in protein degradation pathways associated with neurodegenerative diseases. Curr Pharm Biotechnol 11 , 180-7
    • (2010) Curr Pharm Biotechnol , vol.11 , pp. 180-187
    • Luo, G.R.1    Le, W.D.2
  • 17
    • 75149126921 scopus 로고    scopus 로고
    • Does impairment of the ubiquitin-proteasome system or the autophagy-lysosome pathway predispose individuals to neurodegenerative disorders such as Parkinson's disease
    • Matsuda, N. and Tanaka, K. (2010). Does impairment of the ubiquitin-proteasome system or the autophagy-lysosome pathway predispose individuals to neurodegenerative disorders such as Parkinson's disease? J Alzheimers Dis 19 , 1-9
    • (2010) J Alzheimers Dis , vol.19 , pp. 1-9
    • Matsuda, N.1    Tanaka, K.2
  • 19
    • 67650747654 scopus 로고    scopus 로고
    • Getting a grip on prions: Oligomers, amyloids, and pathological membrane interactions
    • Caughey, B., Baron, G.S., Chesebro, B. and Jeffrey, M. (2009). Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions. Annu Rev Biochem 78 , 177-204
    • (2009) Annu Rev Biochem , vol.78 , pp. 177-204
    • Caughey, B.1    Baron, G.S.2    Chesebro, B.3    Jeffrey, M.4
  • 20
    • 69149089854 scopus 로고    scopus 로고
    • Inclusion formation and neuronal cell death through neuron-toneuron transmission of alpha-synuclein
    • Desplats, P. et al. (2009). Inclusion formation and neuronal cell death through neuron-toneuron transmission of alpha-synuclein. Proc Natl Acad Sci USA 106 , 13010-5
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13010-13015
    • Desplats, P.1
  • 21
    • 43249114934 scopus 로고    scopus 로고
    • Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
    • Kordower, J.H., Chu, Y., Hauser, R.A., Freeman, T.B. and Olanow, C.W. (2008). Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 14 , 504-6
    • (2008) Nat Med , vol.14 , pp. 504-506
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Freeman, T.B.4    Olanow, C.W.5
  • 22
    • 44749090147 scopus 로고    scopus 로고
    • Clearance and deposition of extracellular alpha-synuclein aggregates in microglia
    • Lee, H.J., Suk, J.E., Bae, E.J. and Lee, S.J. (2008). Clearance and deposition of extracellular alpha-synuclein aggregates in microglia. Biochem Biophys Res Commun 372 , 423-8
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 423-428
    • Lee, H.J.1    Suk, J.E.2    Bae, E.J.3    Lee, S.J.4
  • 23
    • 40749094842 scopus 로고    scopus 로고
    • Origins and effects of extracellular alpha-synuclein: Implications in Parkinson's disease
    • Lee, S.J. (2008). Origins and effects of extracellular alpha-synuclein: implications in Parkinson's disease. J Mol Neurosci 34 , 17-22
    • (2008) J Mol Neurosci , vol.34 , pp. 17-22
    • Lee, S.J.1
  • 25
    • 0032540327 scopus 로고    scopus 로고
    • Stabilization of alphasynuclein secondary structure upon binding to synthetic membranes
    • Davidson, W.S., Jonas, A., Clayton, D.F. and George, J.M. (1998). Stabilization of alphasynuclein secondary structure upon binding to synthetic membranes. J Biol Chem 273 , 9443-9
    • (1998) J Biol Chem , vol.273 , pp. 9443-9449
    • Davidson, W.S.1    Jonas, A.2    Clayton, D.F.3    George, J.M.4
  • 26
    • 0034718160 scopus 로고    scopus 로고
    • Properties of NACP/alphasynuclein and its role in Alzheimer's disease
    • Iwai, A. (2000). Properties of NACP/alphasynuclein and its role in Alzheimer's disease. Biochim. Biophys. Acta 1502 , 95-109
    • (2000) Biochim. Biophys. Acta , vol.1502 , pp. 95-109
    • Iwai, A.1
  • 27
    • 0028985267 scopus 로고
    • The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
    • Iwai, A., Masliah, E., Yoshimoto, M., Ge, N., Flanagan, L., de Silva, H.A., Kittel, A. and Saitoh, T. (1995). The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron 14 , 467-75
    • (1995) Neuron , vol.14 , pp. 467-475
    • Iwai, A.1    Masliah, E.2    Yoshimoto, M.3    Ge, N.4    Flanagan, L.5    De Silva, H.A.6    Kittel, A.7    Saitoh, T.8
  • 28
    • 0029904487 scopus 로고    scopus 로고
    • NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
    • Weinreb, P.H., Zhen, W., Poon, A.W., Conway, K.A. and Lansbury, P.T., Jr. (1996). NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35 , 13709-15
    • (1996) Biochemistry , vol.35 , pp. 13709-13715
    • Weinreb, P.H.1    Zhen, W.2    Poon, A.W.3    Conway, K.A.4    Lansbury Jr., P.T.5
  • 29
    • 52349111812 scopus 로고    scopus 로고
    • Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases
    • Tsigelny, I.F. et al. (2008). Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases. PLoS One 3 , e3135
    • (2008) PLoS One , vol.3
    • Tsigelny, I.F.1
  • 30
    • 42549125512 scopus 로고    scopus 로고
    • Review: Familial Parkinson's disease-genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease
    • Schiesling, C., Kieper, N., Seidel, K. and Kruger, R. (2008). Review: Familial Parkinson's disease-genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease. Neuropathol Appl Neurobiol 34 , 255-71
    • (2008) Neuropathol Appl Neurobiol , vol.34 , pp. 255-271
    • Schiesling, C.1    Kieper, N.2    Seidel, K.3    Kruger, R.4
  • 31
    • 84880188930 scopus 로고    scopus 로고
    • Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the Consortium on DLB International Workshop
    • McKeith, I.G. (2006). Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop. J Alzheimers Dis 9 , 417-23
    • (2006) J Alzheimers Dis , vol.9 , pp. 417-423
    • McKeith, I.G.1
  • 32
    • 33144489150 scopus 로고    scopus 로고
    • Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium
    • McKeith, I.G. et al. (2005). Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 65 , 1863-72
    • (2005) Neurology , vol.65 , pp. 1863-1872
    • McKeith, I.G.1
  • 33
    • 21344456506 scopus 로고    scopus 로고
    • Intravesicular localization and exocytosis of alpha-synuclein and its aggregates
    • Lee, H.J., Patel, S. and Lee, S.J. (2005). Intravesicular localization and exocytosis of alpha-synuclein and its aggregates. J Neurosci 25 , 6016-24
    • (2005) J Neurosci , vol.25 , pp. 6016-6024
    • Lee, H.J.1    Patel, S.2    Lee, S.J.3
  • 34
    • 77950571596 scopus 로고    scopus 로고
    • Direct transfer of alphasynuclein from neuron to astroglia causes infl ammatory responses in synucleinopathies
    • Lee, H.J. et al. (2010). Direct transfer of alphasynuclein from neuron to astroglia causes infl ammatory responses in synucleinopathies. J Biol Chem 285 , 9262-72.
    • (2010) J Biol Chem , vol.285 , pp. 9262-9272
    • Lee, H.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.