A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development

PLoS Genetics

Volumn 8, Issue 7, 2012, Pages

  Bharti, Kapil ^a   Gasper, Melanie ^a,c   Ou, Jingxing ^a   Brucato, Martha ^a,d   Clore Gronenborn, Katharina ^a   Pickel, James ^b   Arnheiter, Heinz ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; DICKKOPF HOMOLOG 3 PROTEIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EC; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DICKKOPF HOMOLOG 3 GENE; EMBRYO; FIBROBLAST GROWTH FACTOR 15 GENE; GENE; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY; HOMOZYGOSITY; MITF GENE; MOUSE; NONHUMAN; PAIRED BOX 6 GENE; PIGMENT EPITHELIUM; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA DEVELOPMENT; SIGNAL TRANSDUCTION; SIX HOMEO BOX 6 GENE; TRANSCRIPTION FACTOR EC GENE; VISUAL SYSTEM HOMEOBOX 2 GENE; WNT SIGNALING PATHWAY;

ANIMALS; CELL TRANSDIFFERENTIATION; EMBRYONIC DEVELOPMENT; EYE PROTEINS; FIBROBLAST GROWTH FACTORS; GENE DOSAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; PAIRED BOX TRANSCRIPTION FACTORS; REPRESSOR PROTEINS; RETINA; RETINAL PIGMENT EPITHELIUM; WNT SIGNALING PATHWAY;

MUS; VERTEBRATA;

EID: 84864607961     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002757     Document Type: Article

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