Sunitinib in patients with cisplatin-refractory germ cell tumors

Onkologie

Volumn 35, Issue 7-8, 2012, Pages 455-456

  Reckova, Maria ^a,b,c   Mego, Michal ^b,c   Sycova Mila, Zuzana ^c   Obertova, Jana ^b,c   Svetlovska, Dana ^b,c   Mardiak, Jozef ^b,c  

^a Oncology Clinic Poprad   (Slovakia)

^b Faculty of Natural Sciences   (Slovakia)

^c CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; BEVACIZUMAB; CHORIONIC GONADOTROPIN BETA SUBUNIT; CISPLATIN; OXALIPLATIN; SUNITINIB; VASCULOTROPIN;

CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER REGRESSION; CANCER SURVIVAL; COMPUTER ASSISTED TOMOGRAPHY; DRUG EFFICACY; DRUG MECHANISM; GENE OVEREXPRESSION; GERM CELL TUMOR; HISTOLOGY; HUMAN; LETTER; LUNG METASTASIS; METASTASIS; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; PARAAORTIC LYMPH NODE; PHASE 2 CLINICAL TRIAL (TOPIC); PRIMARY TUMOR; TERATOCARCINOMA; TERATOMA; TREATMENT OUTCOME; TUMOR GROWTH;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHRONIC DISEASE; CISPLATIN; FEMALE; HUMANS; INDOLES; MALE; MIDDLE AGED; NEOPLASMS, GERM CELL AND EMBRYONAL; PYRROLES; SLOVAKIA; TREATMENT OUTCOME;

EID: 84864591995     PISSN: 0378584X     EISSN: 14230240     Source Type: Journal    
DOI: 10.1159/000341079     Document Type: Letter

References (6)

1. Oechsle K, Honecker F, Cheng T, et al.: Preclinical and clinical activity of sunitinib in patients with cisplatin-refractory or multiply relapsed germ cell tumors: A Canadian Urologic ncology Group/German Testicular Cancer Study Group cooperative study. Ann Oncol 2011;22:2654-60.
2. Feldman DR, Turkula S, Ginsberg MS, et al.: Phase II trial of sunitinib in patients with relapsed or refractory germ cell tumors. Invest New Drugs 2010; 28:523-8.
3. Adam M, Schmidt D, Wardelmann E, et al.: Angiogenetic protooncogene ets-1 induced neovascularization is involved in the metastatic process of testicular germ cell tumors. Eur Urol 2003;44:329-36.
4. Fukuda S, Shirahama T, Imazono Y, et al.: Expression of vascular endothelial growth factor in patients with testicular germ cell tumors as an indicator of metastatic disease. Cancer 1999;85:1323-30.
5. Ramasubbaiah R, Brames J, Johnston EL, et al.: Phase II study of oxaliplatin (O) and bevacizumab (B) chemotherapy in refractory germ cell tumors (GCT). J Clin Oncol 2010;28:abstr e15054.
6. Mego M, Recková M, Sycova-Mila Z, et al.: Bevacizumab in a growing teratoma syndrome. Case report. Ann Oncol 2007;18:962-3.