Complete remission after neoadjuvant chemotherapy of an advanced vulvar cancer patient: A case reportjog

Journal of Obstetrics and Gynaecology Research

Volumn 38, Issue 7, 2012, Pages 1036-1039

  Achilli, Chiara ^a   Palaia, Innocenza ^a   Perniola, Giorgia ^a   Donato, Violante Di ^a   Marchetti, Claudia ^a   Panici, Pierluigi Benedetti ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Advanced vulvar cancer; Neoadjuvant chemotherapy; Vulvectomy

Indexed keywords

CISPLATIN; TOPOTECAN;

ABSENCE OF SIDE EFFECTS; ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; ADVANCED CANCER; AGED; ARTICLE; BLOOD TOXICITY; CANCER STAGING; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; LYMPHADENECTOMY; LYMPHADENOPATHY; LYMPHOCELE; OPERATION DURATION; RECTUM HEMORRHAGE; TREATMENT OUTCOME; UROGENITAL SYSTEM EXAMINATION; VULVA CANCER;

AGED; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CISPLATIN; FEMALE; HUMANS; NEOADJUVANT THERAPY; NEOPLASM STAGING; REMISSION INDUCTION; TOPOTECAN; VULVAR NEOPLASMS;

EID: 84864587789     PISSN: 13418076     EISSN: 14470756     Source Type: Journal    
DOI: 10.1111/j.1447-0756.2011.01821.x     Document Type: Article

References (20)

1. Sturgeon SR, Brinton LA, Devesa SS, Kurman RJ. In situ and invasive vulvar cancer incidence trends (1973 to 1987). Am J Obstet Gynecol 1992; 166: 1482-1485.
2. Monaghan JM. The management of carcinoma of the vulva. In: Shepherd JH, Monaghan JM (eds). Clinical Gynaecological Oncology, 2nd edn. Oxford: Blackwell Scientific Publications, 1990; 140-167.
3. Gadducci A, Prato B, Fanucchi A, Bonuccelli A, Cristofani R, Facchini V. Disease-free survival in patients with squamous cell carcinoma of the vulva treated with radical vulvectomy and bilateral inguinal-femoral lymphadenectomy:Analysis of prognostic variables. Cancer J 1993; 6: 269-273.
4. Geisler JP, Wiemann MC, Geisler HE. Pelvic exenteration in the elderly female. J Pelvic Surg 1995; 1: 204-209.
5. Gadducci A, Cionini L, Romanini A et al. Old and new perspectives in the management of high-risk, locally advanced or recurrent, and metastatic vulvar cancer. Oncol Hematol 2006; 60: 227-241.
6. Boronow RC, Hickham BT, Reagan MT et al. Combined therapy as an alternative to exenteration for locally advanced vulvovaginal cancer. Results, complications, dosimetric and surgical considerations. Am J Clin Oncol 1987; 10: 171-181.
7. Gerszten K, Selvaraj RN, Kelley J et al. Preoperative chemoradiation for locally advanced carcinoma of the vulva. Gynecol Oncol 2005; 99: 640-644.
8. Wahlen A, Slater JD, Wagner RJ et al. Concurrent radiation therapy and chemotherapy in the treatment of primary squamous cell carcinoma of the vulva. Cancer 1995; 75: 2289-2294.
9. Gerszten K, Selvaraj RN, Kelley J, Faul C. Preoperative chemoradiation for locally advanced carcinoma of the vulva. Gynecol Oncol 2005; 99: 640-644. Epub 2005 Sep 19.
10. Montana GS, Thomas GM, Moore DH et al. Preoperative chemo-radiation for carcinoma of the vulva with N2/N3 nodes: A Gynecologic Oncology Group study. Int J Radiat Oncol Biol Phys 2000; 48: 1007-1013.
11. Maggioni A, Roviglione G, Landoni F et al. Pelvic exenteration: Ten-year experience at the European Institute of Oncology in Milan. Gynecol Oncol 2009; 114: 64-68. Epub 2009 May 2.
12. Fleisch MC, Pantke P, Beckmann MW et al. Predictors for long-term survival after interdisciplinary salvage surgery for advanced or recurrent gynecologic cancers. J Surg Oncol 2007; 95: 476-484.
13. Lupi G, Raspagliesi F, Zucali R et al. Combined preoperative chemoradiotherapy followed by radical surgery in locally advanced vulvar carcinoma: A pilot study. Cancer 1996; 77: 1472-1478.
14. Shimizu Y, Hasumi K, Masubuchi K. Effective chemotherapy consisting of bleomycin, vincristine, mitomycin C, and cisplatin (BOMP) for a patient with inoperable vulvar cancer. Gynecol Oncol 1990; 36: 423-427.
15. Durrant KR, Mangioni C, Lacave AJ et al. Bleomycin, methotrexate, and CCNU in advanced inoperable squamous cell carcinoma of the vulva: A phase II study of the EORTC Gynaecological Cancer Coop- erative Group (GCCG). Gynecol Oncol 1990; 37: 359-362.
16. Wagenaar HC, Colombo N, Vergote I et al. Bleomycin, methotrexate, and CCNU in locally advanced or recurrent, inoperable, squamous- cell carcinoma of the vulva: An EORTC Gynaecological Cancer Cooperative Group Study. European Organization for Research and Treatment of Cancer. Gynecol Oncol 2001; 81: 348-354.
17. Benedetti-Panici P, Greggi S, Scambia G, Salerno G, Mancuso S. Cisplatin (P), bleomycin (B), and methotrexate (M) preoperative chemotherapy in locally advanced vulvar carcinoma. Gynecol Oncol 1993; 50: 49-53.
18. Geisler JP, Manahan KJ, Buller RE. Neoadjuvant chemotherapy in vulvar cancer: Avoiding primary exenteration. Gynecol Oncol 2006; 100: 53-57.
19. Domingues AP, Mota F, Durão M, Frutuoso C, Amaral N, de Oliveira CF. Neoadjuvant chemotherapy in advanced vulvar cancer. Int J Gynecol Cancer 2010; 20: 294-298.
20. Lorusso D, Pietragalla A, Mainenti S, Masciullo V, Di Vagno G, Scambia G. Review role of topotecan in gynaecological cancers: Current indications and perspectives. Crit Rev Oncol Hematol 2010; 74: 163-174.