Effect of gender, season, and vitamin D status on bone biochemical markers in Saudi diabetes patients

Molecules

Volumn 17, Issue 7, 2012, Pages 8408-8418

  Al Daghri, Nasser M ^a,b   Alkharfy, Khalid M ^a,b,c   Al Othman, Abdulaziz ^b,d   Yakout, Sobhy M ^b   Al Saleh, Yousef ^b   Fouda, Mona A ^e   Sulimani, Riad ^e   Sabico, Shaun ^a,b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

^d KING SAUD UNIVERSITY   (Saudi Arabia)

^e KING KHALID UNIVERSITY HOSPITAL   (Saudi Arabia)

Author keywords

Osteocalcin; Osteoprotegerin; Saudi Arabia; Season; Vitamin D status

Indexed keywords

BIOLOGICAL MARKER; OSTEOCALCIN; VITAMIN D;

ADULT; ANTHROPOMETRY; ARTICLE; BLOOD; BONE; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; SAUDI ARABIA; SEASON; SEXUAL DEVELOPMENT;

ADULT; ANTHROPOMETRY; BIOLOGICAL MARKERS; BONE AND BONES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOCALCIN; SAUDI ARABIA; SEASONS; SEX CHARACTERISTICS; VITAMIN D;

EID: 84864585913     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17078408     Document Type: Article

References (39)

1. Calvo, M.S.; Eyre, D.R.; Gundberg, C.M. Molecular basis and clinical application of biological markers of bone turnover. Endocr. Rev. 1996, 17, 333-368. (Pubitemid 26277979)
2. Midtby, M.; Magnus, J.H.; Joakimsen, R.M. The Tromso Study: A population-based study on the variation in bone formation markers with age, gender, anthropometry and season in both men and women. Osteoporos. Int. 2001, 12, 835-843. (Pubitemid 33086270)
3. Maimoun, L.; Coste, O.; Puech, A.M.; Peruchon, E.; Jaussent, A.; Paris, F.; Rossi, M.; Sultan, C.; Mariano-Goulart, D. No negative impact of reduced leptin secretion on bone metabolism in male decathletes. Eur. J. Appl. Physiol. 2008, 102, 343-351. (Pubitemid 350245959)
4. Rector, R.S.; Rogers, R.; Ruebel, M.; Hinton, P.S. Participation in road cycling vs. running is associated with lower bone mineral density in men. Metabolism 2008, 57, 226-232.
5. Seibel, M.J. Biochemical markers of bone turnover: Part I: Biochemistry and variability. Clin. Biochem. Rev. 2005, 26, 97-122.
6. Compston, J. Monitoring osteoporosis treatment. Best Pract. Res. Clin. Rheumatol. 2009, 23, 781-788.
7. Blumsohn, A.; Eastell, R. The performance and utility of biochemical markers of bone turnover: do we know enough to use them in clinical practice? Ann. Clin. Biochem. 1997, 34, 449-459. (Pubitemid 27379831)
8. Looker, A.C.; Bauer, D.C.; Chesnut, C.H., III.; Gundberg, C.M.; Hochberg, M.C.; Klee, G.; Kleerekoper, M.; Watts, N.B.; Bell, N.H. Clinical use of biochemical markers of bone remodeling: current status and future directions. Osteoporos. Int. 2000, 11, 467-480.
9. Garnero, P. Bone markers in osteoporosis. Curr. Osteoporos. Rep. 2009, 7, 84-90.
10. Schoppet, M.; Preissner, K.T.; Hofbauer, L.C. RANK ligand and osteoprotegerin: Paracrine regulators of bone metabolism and vascular function. Arterioscler. Thromb. Vasc. Biol. 2002, 22, 549-553. (Pubitemid 34408732)
11. Hsu, H.; Lacey, D.L.; Dunstan, C.R.; Solovyev, I.; Colombero, A.; Timms, E.; Tan, H.L.; Elliott, G.; Kelley, M.J.; Sarosi, I.; et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc. Natl. Acad. Sci. USA 1999, 96, 3540-3545. (Pubitemid 29168945)
12. Schoppet, M.; Sattler, A.M.; Schaefer, J.R.; Herzum, M.; Maisch, B.; Hofbauer, L.C. Increased osteoprotegerin serum levels in men with coronary artery disease. J. Clin. Endocrinol. Metab. 2003, 88, 1024-1028. (Pubitemid 36337751)
13. Brown, L.F.; Berse, B.; van de Water, L.; Papadopoulos-Sergiou, A.; Perruzzi, C.A.; Manseau, E.J.; Dvorak, H.F.; Senger, D.R. Expression and distribution of osteopontin in human tissues: Widespread association with luminal epithelial surfaces. Mol. Biol. Cell 1992, 3, 1169-1180. (Pubitemid 23088966)
14. Larson-Meyer, D.E.; Willis, K.S. Vitamin D and athletes. Curr. Sports Med. Rep. 2010, 9, 220-226.
15. Storm, D.; Eslin, R.; Porter, E.S.; Musgrave, K.; Vereault, D.; Patton, C.; Kessenich, C.; Mohan, S.; Chen, T.; Holick, M.F.; Rosen, C.J. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: A randomized placebo-controlled trial. J. Clin. Endocrinol. Metab. 1998, 83, 3817-3825. (Pubitemid 28513556)
16. Woitge, H.W.; Knothe, A.; Witte, K.; Schmidt-Gayk, H.; Ziegler, R.; Lemmer, B.; Seibel, M.J. Circaannual rhythms and interactions of vitamin D metabolites, parathyroid hormone, and biochemical markers of skeletal homeostasis: A prospective study. J. Bone Miner. Res. 2000, 15, 2443-2450.
17. Thomsen, K.; Eriksen, E.F.; Jorgensen, J.C.; Charles, P.; Mosekilde, L. Seasonal variation of serum bone GLA protein. Scand. J. Clin. Lab. Invest. 1989, 49, 605-611.
18. Vanderschueren, D.; Gevers, G.; Dequeker, J.; Geusens, P.; Nijs, J.; Devos, P.; de Roo, M.; Bouillon, R. Seasonal variation in bone metabolism in young healthy subjects. Calcif. Tissue Int. 1991, 49, 84-89.
19. Tsai, K.S.; Wahner, H.W.; Offord, K.P.; Melton, L.J.; Kumar, R.; Riggs, B.L. Effect of aging on vitamin D stores and bone density in women. Calcif. Tissue Int. 1987, 40, 241-243. (Pubitemid 19014735)
20. Maeda, S.S.; Kunii, I.S.; Hayashi, L.F.; Lazaretti-Castro, M. Increases in summer serum 25-hydroxyvitamin D (25OHD) concentrations in elderly subjects in Sao Paulo, Brazil vary with age, gender and ethnicity. BMC Endocr. Disord. 2010, 10, doi:10.1186/1472-6823-10-12.
21. Johnson, L.K.; Hofso, D.; Aasheim, E.T.; Tanbo, T.; Holven, K.B.; Andersen, L.F.; Roislien, J.; Hjelmesaeth, J. Impact of gender on vitamin D deficiency in morbidly obese patients: A cross-sectional study. Eur. J. Clin. Nutr. 2011, 66, 83-90.
22. Nowson, C.A.; Margerison, C. Vitamin D intake and vitamin D status of Australians. Med. J. Aust. 2002, 177, 149-152. (Pubitemid 34918747)
23. Benjamin, A.; Moriakova, A.; Akhter, N.; Rao, D.; Xie, H.; Kukreja, S.; Barengolts, E. Determinants of 25-hydroxyvitamin D levels in African-American and Caucasian male veterans. Osteoporos. Int. 2009, 20, 1795-1803.
24. Douglas, A.S.; Miller, M.H.; Reid, D.M.; Hutchison, J.D.; Porter, R.W.; Robins, S.P. Seasonal differences in biochemical parameters of bone remodelling. J. Clin. Pathol. 1996, 49, 284-289. (Pubitemid 26142890)
25. Epstein, S.; Poser, J.; McClintock, R.; Johnston, C.C., Jr.; Bryce, G.; Hui, S. Differences in serum bone GLA protein with age and sex. Lancet 1984, 1, 307-310. (Pubitemid 14185336)
26. Steinberg, K.K.; Rogers, T.N. Alkaline phosphatase isoenzymes and osteocalcin in serum of normal subjects. Ann. Clin. Lab. Sci. 1987, 17, 241-250. (Pubitemid 17103643)
27. Van Hoof, V.O.; De Broe, M.E. Interpretation and clinical significance of alkaline phosphatase isoenzyme patterns. Crit. Rev. Clin. Lab. Sci. 1994, 31, 197-293. (Pubitemid 24320319)
28. Yasumura, S.; Aloia, J.F.; Gundberg, C.M.; Yeh, J.; Vaswani, A.N.; Yuen, K.; Lo Monte, A.F.; Ellis, K.J.; Cohn, S.H. Serum osteocalcin and total body calcium in normal pre- and postmenopausal women and postmenopausal osteoporotic patients. J. Clin. Endocrinol. Metab. 1987, 64, 681-685. (Pubitemid 17044532)
29. Gundberg, C.M.; Looker, A.C.; Nieman, S.D.; Calvo, M.S. Patterns of osteocalcin and bone specific alkaline phosphatase by age, gender, and race or ethnicity. Bone 2002, 31, 703-708. (Pubitemid 36092094)
30. Mauras, N.; O'Brien, K.O.; Klein, K.O.; Hayes, V. Estrogen suppression in males: Metabolic effects. J. Clin. Endocrinol. Metab. 2000, 85, 2370-2377. (Pubitemid 32269188)
31. Orwoll, E.S.; Belknap, J.K.; Klein, R.F. Gender specificity in the genetic determinants of peak bone mass. J. Bone Miner. Res. 2001, 16, 1962-1971. (Pubitemid 32995387)
32. Cadogan, J.; Blumsohn, A.; Barker, M.E.; Eastell, R. A longitudinal study of bone gain in pubertal girls: Anthropometric and biochemical correlates. J. Bone Miner. Res. 1998, 13, 1602-1612. (Pubitemid 28465301)
33. Christgau, S.; Rosenquist, C.; Alexandersen, P.; Bjarnason, N.H.; Ravn, P.; Fledelius, C.; Herling, C.; Qvist, P.; Christiansen, C. Clinical evaluation of the Serum CrossLaps One Step ELISA, a new assay measuring the serum concentration of bone-derived degradation products of type I collagen C-telopeptides. Clin. Chem. 1998, 44, 2290-2300. (Pubitemid 28511751)
34. Qvist, P.; Christgau, S.; Pedersen, B.J.; Schlemmer, A.; Christiansen, C. Circadian variation in the serum concentration of C-terminal telopeptide of type I collagen (serum CTx): Effects of gender, age, menopausal status, posture, daylight, serum cortisol, and fasting. Bone 2002, 31, 57-61. (Pubitemid 34754426)
35. Denhardt, D.T.; Giachelli, C.M.; Rittling, S.R. Role of osteopontin in cellular signaling and toxicant injury. Ann. Rev. Pharmacol. Toxicol. 2001, 41, 723-749. (Pubitemid 32385904)
36. Mark, M.P.; Prince, C.W.; Oosawa, T.; Gay, S.; Bronckers, A.L.; Butler, W.T. Immunohistochemical demonstration of a 44-KD phosphoprotein in developing rat bones. J. Histochem. Cytochem. 1987, 35, 707-715. (Pubitemid 17121592)
37. Magnusson, P.; Hager, A.; Larsson, L. Serum osteocalcin and bone and liver alkaline phosphatase isoforms in healthy children and adolescents. Pediatr. Res. 1995, 38, 955-961.
38. Szulc, P.; Seeman, E.; Delmas, P.D. Biochemical measurements of bone turnover in children and adolescents. Osteoporos. Int. 2000, 11, 281-294. (Pubitemid 30417180)
39. Al-Daghri, N.M.; Al-Attas, O.S.; Alokail, M.S.; Alkharfy, K.M.; El-Kholie, E.; Yousef, M.; Al-Othman, A.; Al-Saleh, Y.; Sabico, S.; Kumar, S.; et al. Increased vitamin D supplementation recommended during summer season in the gulf region: A counterintuitive seasonal effect in vitamin D levels in adult, overweight and obese Middle Eastern residents. Clin. Endocrinol. (Oxf) 2012, 76, 346-350.