Field application of serodiagnostics to identify elephants with tuberculosis prior to case confirmation by culture

Clinical and Vaccine Immunology

Volumn 19, Issue 8, 2012, Pages 1269-1275

  Lyashchenko, Konstantin P ^a   Greenwald, Rena ^a   Esfandiari, Javan ^a   Mikota, Susan ^b,c   Miller, Michele ^d   Moller, Torsten ^e   Vogelnest, Larry ^f   Gairhe, Kamal P ^e   Robbe Austerman, Suelee ^g   Gai, Jackie ^h   Waters, W Ray ⁱ  

^a CHEMBIO DIAGNOSTIC SYSTEMS INC   (United States)

^b Elephant Care International   (United States)

^c Elephant Sanctuary in Tennessee   (United States)

^d Palm Beach Zoo   (United States)

^e Kolmarden Zoo and Wildlife Park ^*  (Nepal)

^f Taronga Zoo   (Australia)

^g National Veterinary Services Laboratories   (United States)

^h Zoo and Exotic Animal Consultation   (United States)

ⁱ NATIONAL ANIMAL DISEASE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCOBACTERIAL AGENT; BACTERIUM ANTIBODY; CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; MYCOBACTERIUM ANTIGEN;

ANIMAL TISSUE; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIMICROBIAL THERAPY; ARTICLE; AUTOPSY; BACTERIUM CULTURE; BACTERIUM ISOLATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DIAGNOSTIC VALUE; DUAL PATH PLATFORM VETTB ASSAY; ELEPHANT; ELEPHANTTB STAT PAK KIT; FEMALE; IMMUNOASSAY; IMMUNOREACTIVITY; INTERMETHOD COMPARISON; MULTIANTIGEN PRINT IMMUNOASSAY; NONHUMAN; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RELAPSE; SERODIAGNOSIS; TUBERCULOSIS;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CLINICAL LABORATORY TECHNIQUES; DRUG MONITORING; ELEPHANTS; MYCOBACTERIUM TUBERCULOSIS; REAGENT KITS, DIAGNOSTIC; RECURRENCE; SEROLOGIC TESTS; TUBERCULOSIS; VETERINARY MEDICINE;

EID: 84864569008     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00163-12     Document Type: Article

References (29)

1. Angkawanish T, et al. 2010. Mycobacterium tuberculosis infection of domesticated Asian elephants, Thailand. Emerg. Infect. Dis. 16:1949-1951.
2. Boadella M, et al. 2012. Performance of immunochromatographic and ELISA tests for detecting fallow deer infected with Mycobacterium bovis. Prev. Vet. Med. 104:160-164.
3. Boadella M, et al. 2011. Serologic tests for detecting antibodies against Mycobacterium bovis and Mycobacterium avium subspecies paratuberculosis in Eurasian wild boar (Sus scrofa scrofa). J. Vet. Diagn. Invest. 23:77-83.
4. Buddle BM, et al. 2010. Sensitivity, specificity, and confounding factors of novel serological tests used for the rapid diagnosis of bovine tuberculosis in farmed red deer (Cervus elaphus). Clin. Vaccine Immunol. 17:626-630. doi:10.1128/CVI.00010-10.
5. Chambers MA, et al. 2008. Validation of the BrockTB STAT-PAK assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy. J. Clin. Microbiol. 46:1498-1500. (Pubitemid 351563600)
6. Committee on Tuberculosis. 2010. Guidelines for the control of tuberculosis in elephants, p 578-639. Proceedings of 114th Annual Meeting. U.S. Animal Health Association, St. Joseph, MO.
7. Greenwald R, et al. 2009. Highly accurate antibody assays for early and rapid detection of tuberculosis in African and Asian elephants. Clin. Vaccine Immunol. 16:605-612. doi:10.1128/CVI.00038-09.
8. Harmsen D, et al. 2003. Ridom: comprehensive and public sequence database for identification of mycobacterium species. BMC Infect. Dis. 3:26. doi:10.1186/1471-2334-3-26.
9. Higgins J, et al. 2011. Identification of Mycobacterium spp. of veterinary importance using rpoB gene sequencing. BMC Vet. Res. 7:77.
10. Lacasse C, et al. 2007. Two cases of atypical mycobacteriosis caused by Mycobacterium szulgai associated with mortality in captive African elephants (Loxodonta africana). J. Zoo Wildl. Med. 38:101-107. (Pubitemid 46525227)
11. Larsen RS, et al. 2000. Evaluation of a multiple-antigen enzyme-linked immunosorbent assay for detection of Mycobacterium tuberculosis infection in captive elephants. J. Zoo Wildl. Med. 31:291-302.
12. Lesellier S, et al. 2009. Immunological responses and protective immunity in BCG vaccinated badgers following endobronchial infection with Mycobacterium bovis. Vaccine 27:402-409. doi:10.1016/j.vaccine.2008.10.068.
13. Lewerin SS, et al. 2005. Outbreak of Mycobacterium tuberculosis infection among captive Asian elephants in a Swedish zoo. Vet. Rec. 156:171-175.
14. Lyashchenko K, et al. 2004. Association of tuberculin-boosted antibody responses with pathology and cell-mediated immunity in cattle vaccinated with Mycobacterium bovis BCG and infected with M. bovis. Infect. Immun. 72:2462-2467. (Pubitemid 38542370)
15. Lyashchenko KP, et al. 2006. Tuberculosis in elephants: antibody responses to defined antigens of Mycobacterium tuberculosis, potential for early diagnosis, and monitoring of treatment. Clin. Vaccine Immunol. 13:722-732. doi:10.1128/CVI.00133-06.
16. Lyashchenko KP, et al. 2007. PrimaTB STAT-PAK assay, a novel rapid lateral-flow test for tuberculosis in nonhuman primates. Clin. Vaccine Immunol. 14:1158-1164. doi:10.1128/CVI.00230-07. (Pubitemid 47518082)
17. Lyashchenko KP, et al. 2008. Animal-side assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife. Vet. Microbiol. 132:283-292.
18. Lyashchenko KP, et al. 2011. Diagnostic value of animal-side antibody assays for rapid detection of Mycobacterium bovis or Mycobacterium microti infection in South American camelids. Clin. Vaccine Immunol. 18:2143-2147. doi:10.1128/CVI.05386-11.
19. Michalak K, et al. 1998. Mycobacterium tuberculosis infection as a zoonotic disease: transmission between humans and elephants. Emerg. Infect. Dis. 4:283-287. (Pubitemid 28311216)
20. Mikota SK. 2008. Tuberculosis in elephants, p 355-364. In Fowler ME, Miller RE (ed), Zoo and wild animal medicine, current therapy, 6th ed. Saunders Elsevier, St. Louis, MO.
21. Mikota SK, Larsen RS, Montali RJ. 2000. Tuberculosis in elephants in North America. Zoo Biol. 19:393-403. doi:10.1002/1098-2361(2000)19: 5〈393::AID-ZOO9〉3.0.CO;2-T.
22. Mikota SK, et al. 2001. Epidemiology and diagnosis of Mycobacteriumtuberculosis in captive Asian elephants (Elephas maximus). J. Zoo Wildl. Med. 32:1-16. (Pubitemid 33695861)
23. Mikota SK, Maslow JN. 2011. Tuberculosis at the human-animal interface: an emerging disease of elephants. Tuberculosis 91:208-211. doi:10.1016/j.tube. 2011.02.007.
24. Moller T, Roken B, Petersson L, Vitaud C, Lyashchenko K. 2005. Preliminary results of a new serological test for detection of TB infection (Mycobacterium tuberculosis) in elephants (Elephas maximus and Loxodonta africanum) - Swedish case studies. Verh. ber. Erkrg. Zootiere 42:173-181.
25. Montali RJ, Mikota SK, Cheng LI. 2001. Mycobacterium tuberculosis in zoo and wildlife species. Rev. Sci. Tech. 20:291-303. (Pubitemid 33585269)
26. Murphree R, Warkentin JV, Dunn JR, Schaffner W, Jones TF. 2011. Elephant-to-human transmission of tuberculosis, 2009. Emerg. Infect. Dis. 17:366-371.
27. Oh P, et al. 2002. Human exposure following Mycobacterium tuberculosis infection of multiple animal species in a metropolitan zoo. Emerg. Infect. Dis. 8:1290-1293. (Pubitemid 35334703)
28. Rhodes SG, et al. 2011. Comparative study of IFNγ and antibody tests for feline tuberculosis. Vet. Immunol. Immunopathol. 144:129-134. doi: 10.1016/j.vetimm.2011.07.020.
29. Waters, WR, et al. 2011. Bovine tuberculosis in a Nebraska herd of farmed elk and fallow deer: a failure of the tuberculin skin test and opportunities for serodiagnosis. Vet. Med. Int. 2011:953985.