No evidence for additional blood-brain barrier P-glycoprotein dysfunction in Alzheimer's disease patients with microbleeds

Journal of Cerebral Blood Flow and Metabolism

Volumn 32, Issue 8, 2012, Pages 1468-1471

  Van Assema, Daniëlle M E ^a,b   Goos, Jeroen D C ^b   Van Der Flier, Wiesje M ^a,b   Lubberink, Mark ^a,c   Boellaard, Ronald ^a   Windhorst, Albert D ^a   Scheltens, Philip ^b   Lammertsma, Adriaan A ^a   Van Berckel, Bart N M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

(R) 11C verapamil; Alzheimer's disease; blood brain barrier; cerebral amyloid angiopathy; P glycoprotein; positron emission tomography

Indexed keywords

GLYCOPROTEIN P; TRACER; UNCLASSIFIED DRUG; VERAPAMIL C 11;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; BRAIN HEMORRHAGE; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN FUNCTION;

AGED; ALZHEIMER DISEASE; BLOOD-BRAIN BARRIER; CARBON RADIOISOTOPES; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL HEMORRHAGE; FEMALE; HUMANS; MALE; MIDDLE AGED; P-GLYCOPROTEIN; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; VERAPAMIL;

EID: 84864568362     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2012.64     Document Type: Article

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