Not all mice are equal: Welfare implications of behavioural habituation profiles in four 129 mouse substrains

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Boleij, Hetty ^a,b   Salomons, Amber R ^a,b   van Sprundel, Mariska ^a   Arndt, Saskia S ^a,b   Ohl, Frauke ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE BEHAVIOR; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; AROUSAL; ARTICLE; AVOIDANCE BEHAVIOR; EMOTIONALITY; ENVIRONMENTAL EXPOSURE; EVOLUTIONARY ADAPTATION; EXPERIMENTAL ANIMAL WELFARE; EXPLORATORY BEHAVIOR; HABITUATION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; OPEN FIELD BEHAVIOR; STRAIN DIFFERENCE;

ANIMAL WELFARE; ANIMALS; AROUSAL; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; CORTICOSTERONE; CROSSES, GENETIC; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; FEMALE; HABITUATION, PSYCHOPHYSIOLOGIC; LATENCY PERIOD (PSYCHOLOGY); LOCOMOTION; MALE; MICE; MICE, 129 STRAIN; RISK ASSESSMENT;

ANIMALIA; MUS;

EID: 84864561223     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042544     Document Type: Article

References (47)

1. Brambell FWR, (1965) Report of the technical committee to enquire into the welfare of animals kept under intensive livestock husbandry systems.
2. Boissy A, Manteuffel G, Jensen MB, Moe RO, Spruijt B, et al. (2007) Assessment of positive emotions in animals to improve their welfare. Physiol Behav 92(3): 375-397.
3. Yeates JW, Main DCJ, (2008) Assessment of positive welfare: A review. Vet J 175 (3): 293-300.
4. Ohl F, van der Staay FJ, (2012) Animal welfare: At the interface between science and society. Vet J 192 (1): 13-19.
5. Bracke MBM, Hopster H, (2006) Assessing the importance of natural behavior for animal welfare. J Agric Environ Ethics 19 (1): 77-89.
6. Salomons AR, Arndt SS, Ohl F, (2009) Anxiety in relation to animal environment and welfare. Scand J Lab Anim Sci 36 (1): 37-45.
7. Korte SM, Olivier B, Koolhaas JM, (2007) A new animal welfare concept based on allostasis. Physiol Behav 92 (3): 422-428.
8. Ohl F, Arndt SS, van der Staay FJ, (2008) Pathological anxiety in animals. Vet J 175 (1): 18-26.
9. Knierim U, Winckler C, (2009) On-farm welfare assessment in cattle: Validity, reliability and feasibility issues and future perspectives with special regard to the welfare quality® approach. Anim Welf 18 (4): 451-458.
10. Webster AJF, (1994) Animal welfare: A cool eye towards eden. Londen, UK: Blackwell Science ltd.
11. Jensen P, (2010) Domestication, selection, behaviour and welfare of animals- genetic mechanisms for rapid responses. Anim Welf 19 (SUPPL. 1): 7-9.
12. Belzung C, Griebel G, (2001) Measuring normal and pathological anxiety-like behaviour in mice: A review. Behav Brain Res 125 (1-2): 141-149.
13. Ohl F, Roedel A, Binder E, Holsboer F, (2003) Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice. Eur J Neurosci 17: 128-136.
14. Laarakker MC, Ohl F, Van Lith HA, (2008) Chromosomal assignment of quantitative trait loci influencing modified hole board behavior in laboratory mice using consomic strains, with special reference to anxiety-related behavior and mouse chromosome 19. Behav Genet 38 (2): 159-184.
15. Clément Y, Guisquet AML, Venault P, Chapouthier G, Belzung C, (2009) Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation. PLoS One 4 (11): e7745.
16. Crabbe JC, Wahlsten D, Dudek BC, (1999) Genetics of mouse behavior: Interactions with laboratory environment. Science 284 (5420): 1670-1672.
17. van der Staay FJ, Arndt SS, Nordquist RE, (2010) The standardization-generalization dilemma: A way out. Genes Brain Behav 9 (8): 849-855.
18. Abramov U, Puussaar T, Raud S, Kurrikoff K, Vasar E, (2008) Behavioural differences between C57BL/6 and 129S6/SvEv strains are reinforced by environmental enrichment. Neurosci Lett 443 (3): 223-227.
19. Pothion S, Bizot J, Trovero F, Belzung C, (2004) Strain differences in sucrose preference and in the consequences of unpredictable chronic mild stress. Behav Brain Res 155 (1): 135-146.
20. Salomons AR, Kortleve T, Reinders NR, Kirchhoff S, Arndt SS, et al. (2010) Susceptibility of a potential animal model for pathological anxiety to chronic mild stress. Behav Brain Res 209 (2): 241-248.
21. Ohl F, Roedel A, Storch C, Holsboer F, Landgraf R, (2002) Cognitive performance in rats differing in their inborn anxiety. Behav Neurosci 116 (3): 464-471.
22. Livesey PJ, (1986) Learning and emotion: A biological synthesis. Hillsdale, New Jersey: Lawrence Erlbaum Associates, publishers.
23. Eisenstein EM, Eisenstein D, (2006) A behavioral homeostasis theory of habituation and sensitization: II. further developments and predictions. Rev Neurosci 17 (5): 533-557.
24. Salomons AR, van Luijk JAKR, Reinders NR, Kirchhoff S, Arndt SS, et al. (2010) Identifying emotional adaptation: Behavioural habituation to novelty and immediate early gene expression in two inbred mouse strains. Genes Brain Behav 9(1): 1-10.
25. National Research Council (2010) Guide for the care and use of laboratory animals. Washington, DC: National Academies Press.
26. Simpson EM, Linder CC, Sargent EE, Davidsson MT, Mobraaten LE, et al. (1997) Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice. Nat Genet 16.
27. Tang X, Sanford LD, (2005) Home cage activity and activity-based measures of anxiety in 129P3/J, 129X1/SvJ and C57BL/6J mice. Physiol Behav 84 (1): 105-115.
28. Bothe GWM, Bolivar VJ, Vedder MJ, Geistfeld JG, (2005) Behavioral differences among fourteen inbred mouse strains commonly used as disease models. Comp Med 55 (4): 326-334.
29. Bothe GWM, Bolivar VJ, Vedder MJ, Geistfeld JG, (2004) Genetic and behavioral differences among five inbred mouse strains commonly used in the production of transgenic and knockout mice. Genes Brain Behav 3 (3): 149-157.
30. Cook MN, Bolivar VJ, McFadyen MP, Flaherty L, (2002) Behavioral differences among 129 substrains: Implications for knockout and transgenic mice. Behav Neurosci 116 (4): 600-611.
31. Ohl F, Sillaber I, Binder E, Keck ME, Holsboer F, (2001) Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole board test. J Psychiatr Res 35: 147-154.
32. Salomons AR, Bronkers G, Kirchhoff S, Arndt SS, Ohl F, (2010) Behavioural habituation to novelty and brain area specific immediate early gene expression in female mice of two inbred strains. Behav Brain Res 215 (1): 95-101.
33. Bolivar VJ, (2009) Intrasession and intersession habituation in mice: From inbred strain variability to linkage analysis. Neurobiol Learn Mem 92 (2): 206-214.
34. Pratte M, Jamon M, (2009) Detection of social approach in inbred mice. Behav Brain Res 203 (1): 54-64.
35. de Visser L, van den Bos R, Kuurman WW, Kas MJH, Spruijt BM, (2006) Novel approach to the behavioural characterization of inbred mice: Automated home cage observations. Genes Brain Behav 5 (6): 458-466.
36. Sik A, van Nieuwehuyzen P, Prickaerts J, Blokland A, (2003) Performance of different mouse strains in an object recognition task. Behav Brain Res 147 (1-2): 49-54.
37. Gray JA, (1982) The neuropsychology of anxiety. Oxford and New York: Oxford University Press New York, Clarendon Press Oxford.
38. O'Keefe J, (1999) Do hippocampal pyramidal cells signal non-spatial as well as spatial information? Hippocampus 9 (4): 352-364. 2-1.
39. Montkowski A, Poettig M, Mederer A, Holsboer F, (1997) Behavioural performance in three substrains of mouse strain 129. Brain Res 762 (1-2): 12-18.
40. Kim D, Chae S, Lee J, Yang H, Shin HS, (2005) Variations in the behaviors to novel objects among five inbred strains of mice. Genes Brain Behav 4 (5): 302-306.
41. Salomons AR, Arndt SS, Ohl F, (2012) Impact of anxiety-profiles on cognitive performance in BALB/c and 129P2 mice. Cogn Affect and Behav Neurosci in press.
42. Casellas J, (2011) Inbred mouse strains and genetic stability: A review. Anim 5 (1): 1-7.
43. Chesler EJ, Wilson SG, Lariviere WR, Rodriguez-Zas SL, Mogil JS, (2002) Identification and ranking of genetic and laboratory environment factors influencing a behavioral trait, thermal nociception, via computational analysis of a large data archive. Neurosci Biobehav Rev 26 (8): 907-923.
44. Belzung C, Berton F, (1997) Further pharmacological validation of the BALB/c neophobia in the free exploratory paradigm as an animal model of trait anxiety. Behav Pharmacol 8 (6-7): 541-548.
45. Clément Y, Calatayud F, Belzung C, (2002) Genetic basis of anxiety-like behaviour: A critical review. Brain Res Bull 57 (1): 57-71.
46. Camp M, Norcross M, Whittle N, Feyder M, D'Hanis W, et al. (2009) Impaired pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain. Genes Brain Behav 8 (8): 744-752.
47. Hefner K, Whittle N, Juhasz J, Norcross M, Karlsson R, et al. (2008) Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain. J Neurosci 28 (32): 8074-8085.