메뉴 건너뛰기




Volumn 14, Issue 2, 2012, Pages 138-147

Clinical trials in acute repetitive seizures and status epilepticus

Author keywords

Clinical trial; Repetitive seizure; Status epilepticus; Tonic clonic

Indexed keywords

ACETAZOLAMIDE; CLOBAZAM; DIAZEPAM; FOSPHENYTOIN SODIUM; LORAZEPAM; MIDAZOLAM; PENTOBARBITAL; PHENOBARBITAL; PHENYTOIN; PLACEBO; PROPOFOL; THIOPENTAL; VALPROIC ACID;

EID: 84864535517     PISSN: 12949361     EISSN: 19506945     Source Type: Journal    
DOI: 10.1684/epd.2012.0514     Document Type: Conference Paper
Times cited : (21)

References (50)
  • 1
    • 34547699419 scopus 로고    scopus 로고
    • Randomized study of intravenous valproate and phenytoin in status epilepticus
    • Agarwal P, Kumar N, Chandra R, Gupta G, Antony AR, Garg N. Randomized study of intravenous valproate and phenytoin in status epilepticus. Seizure 2007; 16: 527-32.
    • (2007) Seizure , vol.16 , pp. 527-532
    • Agarwal, P.1    Kumar, N.2    Chandra, R.3    Gupta, G.4    Antony, A.R.5    Garg, N.6
  • 2
    • 0035975408 scopus 로고    scopus 로고
    • A comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus
    • Erratum in: 2001; 345: 1860
    • Alldredge BK, Gelb AM, Isaacs SM, et al. A comparison of lorazepam, diazepam, and placebo for the treatment of out-of-hospital status epilepticus. N Engl J Med 2001; 345: 631-7. Erratum in: 2001; 345: 1860.
    • (2001) N Engl J Med , vol.345 , pp. 631-637
    • Alldredge, B.K.1    Gelb, A.M.2    Isaacs, S.M.3
  • 3
    • 0029163420 scopus 로고
    • Lorazepam versus diazepam in the acute treatment of epileptic seizures and status epilepticus
    • Appleton R, Sweeney A, Choonara I, Robson J, Molyneux E. Lorazepam versus diazepam in the acute treatment of epileptic seizures and status epilepticus. Dev Med Child Neurol 1995; 37: 682-8.
    • (1995) Dev Med Child Neurol , vol.37 , pp. 682-688
    • Appleton, R.1    Sweeney, A.2    Choonara, I.3    Robson, J.4    Molyneux, E.5
  • 5
    • 0031797441 scopus 로고    scopus 로고
    • Treating repetitive seizures with a rectal diazepam formulation: A randomized study
    • The North American Diastat Study Group
    • Cereghino JJ, Mitchell WG, Murphy J, Kriel RL, Rosenfeld WE, Trevathan E. Treating repetitive seizures with a rectal diazepam formulation: a randomized study. The North American Diastat Study Group. Neurology 1998; 51: 1274-82.
    • (1998) Neurology , vol.51 , pp. 1274-1282
    • Cereghino, J.J.1    Mitchell, W.G.2    Murphy, J.3    Kriel, R.L.4    Rosenfeld, W.E.5    Trevathan, E.6
  • 6
    • 0036895147 scopus 로고    scopus 로고
    • Rectal diazepam gel for treatment of acute repetitive seizures in adults
    • North American Diastat Study Group
    • Cereghino JJ, Cloyd JC, Kuzniecky RI; North American Diastat Study Group. Rectal diazepam gel for treatment of acute repetitive seizures in adults. Arch Neurol 2002; 59: 1915-20.
    • (2002) Arch Neurol , vol.59 , pp. 1915-1920
    • Cereghino, J.J.1    Cloyd, J.C.2    Kuzniecky, R.I.3
  • 7
    • 0030948363 scopus 로고    scopus 로고
    • A prospective, randomized study comparing intramuscular midazolam with intravenous diazepam for the treatment of seizures in children
    • Chamberlain JM, Altieri MA, Futterman C, Young GM, Ochsenschlager DW, Waisman Y. A prospective, randomized study comparing intramuscular midazolam with intravenous diazepam for the treatment of seizures in children. Pediatr Emerg Care 1997; 13: 92-4.
    • (1997) Pediatr Emerg Care , vol.13 , pp. 92-94
    • Chamberlain, J.M.1    Altieri, M.A.2    Futterman, C.3    Young, G.M.4    Ochsenschlager, D.W.5    Waisman, Y.6
  • 8
    • 80053595048 scopus 로고    scopus 로고
    • Established status epilepticus treatment trial (ESETT)
    • Cock H. Established status epilepticus treatment trial (ESETT). Epilepsia 2011; 52: 50-2.
    • (2011) Epilepsia , vol.52 , pp. 50-52
    • Cock, H.1
  • 10
    • 0032566037 scopus 로고    scopus 로고
    • A comparison of rectal diazepam gel and placebo for acute repetitive seizures
    • Dreifuss FE, Rosman NP, Cloyd JC, et al. A comparison of rectal diazepam gel and placebo for acute repetitive seizures. N Engl J Med 1998; 338: 1869-75.
    • (1998) N Engl J Med , vol.338 , pp. 1869-1875
    • Dreifuss, F.E.1    Rosman, N.P.2    Cloyd, J.C.3
  • 11
    • 0027272387 scopus 로고
    • Treatment of convulsive status epilepticus. Recommendations of the Epilepsy Foundation of America's Working Group on status epilepticus
    • EFA Working Group on Status Epilepticus
    • EFA Working Group on Status Epilepticus. Treatment of convulsive status epilepticus. Recommendations of the Epilepsy Foundation of America's Working Group on status epilepticus. JAMA 1993; 270: 854-9.
    • (1993) JAMA , vol.270 , pp. 854-859
  • 12
    • 0019947210 scopus 로고
    • Clobazam in catamenial epilepsy. A model for evaluating anticonvulsants
    • Feely M, Calvert R, Gibson J. Clobazam in catamenial epilepsy. A model for evaluating anticonvulsants. Lancet 1982; 2: 71-3.
    • (1982) Lancet , vol.2 , pp. 71-73
    • Feely, M.1    Calvert, R.2    Gibson, J.3
  • 13
    • 0036247445 scopus 로고    scopus 로고
    • Effects of intranasal midazolam and rectal diazepam on acute convulsions in children: Prospective randomized study
    • Fisgin T, Gurer Y, Tezic T, et al. Effects of intranasal midazolam and rectal diazepam on acute convulsions in children: prospective randomized study. J Child Neurol 2002; 17: 123-6.
    • (2002) J Child Neurol , vol.17 , pp. 123-126
    • Fisgin, T.1    Gurer, Y.2    Tezic, T.3
  • 14
    • 53549097641 scopus 로고    scopus 로고
    • Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin
    • Gilad R, Izkovitz N, Dabby R, et al. Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin. Acta Neurol Scand 2008; 118: 296-300.
    • (2008) Acta Neurol Scand , vol.118 , pp. 296-300
    • Gilad, R.1    Izkovitz, N.2    Dabby, R.3
  • 15
    • 38949184571 scopus 로고    scopus 로고
    • Intravenous levetiracetam in children with epilepsy
    • Goraya JS, Khurana DS, Valencia I, et al. Intravenous levetiracetam in children with epilepsy. Pediatr Neurol 2008; 38: 177-80.
    • (2008) Pediatr Neurol , vol.38 , pp. 177-180
    • Goraya, J.S.1    Khurana, D.S.2    Valencia, I.3
  • 16
    • 34249872188 scopus 로고    scopus 로고
    • Efficacy of intravenous midazolam for status epilepticus in childhood
    • Hayashi K, Osawa M, Aihara M, et al. Efficacy of intravenous midazolam for status epilepticus in childhood. Pediatr Neurol 2007; 36: 366-72.
    • (2007) Pediatr Neurol , vol.36 , pp. 366-372
    • Hayashi, K.1    Osawa, M.2    Aihara, M.3
  • 17
    • 77955371725 scopus 로고    scopus 로고
    • Intranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy
    • Holsti M, Dudley N, Schunk J, et al. Intranasal midazolam vs rectal diazepam for the home treatment of acute seizures in pediatric patients with epilepsy. Arch Pediatr Adolesc Med 2010; 164: 747-53.
    • (2010) Arch Pediatr Adolesc Med , vol.164 , pp. 747-753
    • Holsti, M.1    Dudley, N.2    Schunk, J.3
  • 18
    • 78650789188 scopus 로고    scopus 로고
    • Intravenous lacosamide for treatment of status epilepticus
    • Kellinghaus C, Berning S, Immisch I, et al. Intravenous lacosamide for treatment of status epilepticus. Acta Neurol Scand 2011; 123: 137-41.
    • (2011) Acta Neurol Scand , vol.123 , pp. 137-141
    • Kellinghaus, C.1    Berning, S.2    Immisch, I.3
  • 21
    • 0033771030 scopus 로고    scopus 로고
    • The safety of rapid valproic acid infusion
    • Limdi NA, Faught E. The safety of rapid valproic acid infusion. Epilepsia 2000; 41: 1342-5.
    • (2000) Epilepsia , vol.41 , pp. 1342-1345
    • Limdi, N.A.1    Faught, E.2
  • 22
    • 1842636822 scopus 로고    scopus 로고
    • Comparison of intranasal midazolam with intravenous diazepam for treating acute seizures in children
    • Mahmoudian T, Zadeh MM. Comparison of intranasal midazolam with intravenous diazepam for treating acute seizures in children. Epilepsy Behav 2004; 5: 253-5.
    • (2004) Epilepsy Behav , vol.5 , pp. 253-255
    • Mahmoudian, T.1    Zadeh, M.M.2
  • 23
    • 22144451868 scopus 로고    scopus 로고
    • Safety and efficacy of buccal midazolam versus rectal diazepam for emergency treatment of seizures in children: A randomised controlled trial
    • McIntyre J, Robertson S, Norris E, et al. Safety and efficacy of buccal midazolam versus rectal diazepam for emergency treatment of seizures in children: a randomised controlled trial. Lancet 2005; 366: 205-10.
    • (2005) Lancet , vol.366 , pp. 205-210
    • McIntyre, J.1    Robertson, S.2    Norris, E.3
  • 24
    • 34547881203 scopus 로고    scopus 로고
    • Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: A randomized controlled trial
    • Mehta V, Singhi P, Singhi S. Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: a randomized controlled trial. J Child Neurol 2007; 22: 1191-7.
    • (2007) J Child Neurol , vol.22 , pp. 1191-1197
    • Mehta, V.1    Singhi, P.2    Singhi, S.3
  • 25
    • 33744741385 scopus 로고    scopus 로고
    • EFNS guideline on the management of status epilepticus
    • Meierkord H, Boon P, Engelsen B, et al. EFNS guideline on the management of status epilepticus. Eur J Neurol 2006; 13: 445-50.
    • (2006) Eur J Neurol , vol.13 , pp. 445-450
    • Meierkord, H.1    Boon, P.2    Engelsen, B.3
  • 26
    • 77649174487 scopus 로고    scopus 로고
    • EFNS guideline on the management of status epilepticus in adults
    • Meierkord H, Boon P, Engelsen B, et al. EFNS guideline on the management of status epilepticus in adults. Eur J Neurol 2010; 17: 348-55.
    • (2010) Eur J Neurol , vol.17 , pp. 348-355
    • Meierkord, H.1    Boon, P.2    Engelsen, B.3
  • 27
    • 33845543071 scopus 로고    scopus 로고
    • Treatment of status epilepticus in adults: Guidelines of the Italian league against epilepsy
    • Minicucci F, Muscas G, Perucca E, Capovilla G, Vigevano F, Tinuper P. Treatment of status epilepticus in adults: guidelines of the Italian league against epilepsy. Epilepsia 2006; 47: 9-15.
    • (2006) Epilepsia , vol.47 , pp. 9-15
    • Minicucci, F.1    Muscas, G.2    Perucca, E.3    Capovilla, G.4    Vigevano, F.5    Tinuper, P.6
  • 28
    • 33747070541 scopus 로고    scopus 로고
    • Sodium valproate vs phenytoin in status epilepticus: A pilot study
    • Misra UK, Kalita J, Patel R. Sodium valproate vs phenytoin in status epilepticus: a pilot study. Neurology 2006; 67: 340-2.
    • (2006) Neurology , vol.67 , pp. 340-342
    • Misra, U.K.1    Kalita, J.2    Patel, R.3
  • 29
    • 38049048636 scopus 로고    scopus 로고
    • Comparison of buccal midazolam with rectal diazepam in the treatment of prolonged seizures in Ugandan children: A randomized clinical trial
    • Mpimbaza A, Ndeezi G, Staedke S, Rosenthal PJ, Byarugaba J. Comparison of buccal midazolam with rectal diazepam in the treatment of prolonged seizures in Ugandan children: a randomized clinical trial. Pediatrics 2008; 121: e58-64.
    • (2008) Pediatrics , vol.121
    • Mpimbaza, A.1    Ndeezi, G.2    Staedke, S.3    Rosenthal, P.J.4    Byarugaba, J.5
  • 30
    • 79960127918 scopus 로고    scopus 로고
    • Buccal midazolam or rectal diazepam for treatment of residential adult patients with serial seizures or status epilepticus
    • Nakken KO, Lossius MI. Buccal midazolam or rectal diazepam for treatment of residential adult patients with serial seizures or status epilepticus. Acta Neurol Scand 2011; 24: 99-103.
    • (2011) Acta Neurol Scand , vol.24 , pp. 99-103
    • Nakken, K.O.1    Lossius, M.I.2
  • 31
    • 0036287648 scopus 로고    scopus 로고
    • Comparative audit of intravenous lorazepam and diazepam in the emergency treatment of convulsive status epilepticus in children
    • Qureshi A, Wassmer E, Davies P, Berry K, Whitehouse WP. Comparative audit of intravenous lorazepam and diazepam in the emergency treatment of convulsive status epilepticus in children. Seizure 2002; 11: 141-4.
    • (2002) Seizure , vol.11 , pp. 141-144
    • Qureshi, A.1    Wassmer, E.2    Davies, P.3    Berry, K.4    Whitehouse, W.P.5
  • 32
    • 0037465779 scopus 로고    scopus 로고
    • Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoring
    • Rose AB, McCabe PH, Gilliam FG, et al. Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoring. Neurology 2003; 60: 975-8.
    • (2003) Neurology , vol.60 , pp. 975-978
    • Rose, A.B.1    McCabe, P.H.2    Gilliam, F.G.3
  • 34
    • 69249153500 scopus 로고    scopus 로고
    • Review of the efficacy of rectal paraldehyde in the management of acute and prolonged tonic-clonic convulsions
    • Rowland AG, Gill AM, Stewart AB, et al. Review of the efficacy of rectal paraldehyde in the management of acute and prolonged tonic-clonic convulsions. Arch Dis Child 2009; 94: 720-3.
    • (2009) Arch Dis Child , vol.94 , pp. 720-723
    • Rowland, A.G.1    Gill, A.M.2    Stewart, A.B.3
  • 35
    • 0033799614 scopus 로고    scopus 로고
    • Is intranasal midazolam an effective rescue medication in adolescents and adults with severe epilepsy?
    • Scheepers M, Scheepers B, Clarke M, Comish S, Ibitoye M. Is intranasal midazolam an effective rescue medication in adolescents and adults with severe epilepsy? Seizure 2000; 9: 417-22.
    • (2000) Seizure , vol.9 , pp. 417-422
    • Scheepers, M.1    Scheepers, B.2    Clarke, M.3    Comish, S.4    Ibitoye, M.5
  • 36
    • 0033056940 scopus 로고    scopus 로고
    • Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: A randomised trial
    • Scott RC, Besag FM, Neville BG. Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial. Lancet 1999; 353: 623-6.
    • (1999) Lancet , vol.353 , pp. 623-626
    • Scott, R.C.1    Besag, F.M.2    Neville, B.G.3
  • 37
    • 0023837005 scopus 로고
    • Treatment of status epilepticus: A prospective comparison of diazepam and phenytoin versus phenobarbital and optional phenytoin
    • Shaner DM, McCurdy SA, Herring MO, Gabor AJ. Treatment of status epilepticus: a prospective comparison of diazepam and phenytoin versus phenobarbital and optional phenytoin. Neurology 1988; 38: 202-7.
    • (1988) Neurology , vol.38 , pp. 202-207
    • Shaner, D.M.1    McCurdy, S.A.2    Herring, M.O.3    Gabor, A.J.4
  • 39
    • 80053597247 scopus 로고    scopus 로고
    • Super-refractory status epilepticus: An approach to therapy in this difficult clinical situation
    • Shorvon S. Super-refractory status epilepticus: an approach to therapy in this difficult clinical situation. Epilepsia 2011; 52: 53-6.
    • (2011) Epilepsia , vol.52 , pp. 53-56
    • Shorvon, S.1
  • 40
    • 80053616375 scopus 로고    scopus 로고
    • The treatment of super-refractory status epilepticus: A critical review of available therapies and a clinical treatment protocol
    • Shorvon S, Ferlisi M. The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol. Brain 2011; 134: 2802-18.
    • (2011) Brain , vol.134 , pp. 2802-2818
    • Shorvon, S.1    Ferlisi, M.2
  • 41
    • 84864544707 scopus 로고    scopus 로고
    • The outcome of therapies used in refractory and super-refractory status epilepticus: A review of the published literature and recommendations for therapy
    • in press
    • Shorvon S, Ferlisi M. The outcome of therapies used in refractory and super-refractory status epilepticus: a review of the published literature and recommendations for therapy. Brain 2012 (in press).
    • (2012) Brain
    • Shorvon, S.1    Ferlisi, M.2
  • 42
    • 47249113436 scopus 로고    scopus 로고
    • The drug treatment of status epilepticus in Europe: Consensus document from a workshop at the first London Colloquium on Status Epilepticus
    • TaskForce on Status Epilepticus of the ILAE Commission for European Affairs
    • Shorvon S, Baulac M, Cross H, Trinka E, Walker M; TaskForce on Status Epilepticus of the ILAE Commission for European Affairs. The drug treatment of status epilepticus in Europe: consensus document from a workshop at the first London Colloquium on Status Epilepticus. Epilepsia 2008; 49: 1277-85.
    • (2008) Epilepsia , vol.49 , pp. 1277-1285
    • Shorvon, S.1    Baulac, M.2    Cross, H.3    Trinka, E.4    Walker, M.5
  • 43
    • 80053598304 scopus 로고    scopus 로고
    • RAMPART (Rapid Anticonvulsant Medication Prior to Arrival Trial): A double-blind randomized clinical trial of the efficacy of intramuscular midazolam versus intravenous lorazepam in the prehospital treatment of status epilepticus by paramedics
    • Neurological Emergency Treatment Trial (NETT) investigators
    • Silbergleit R, Lowenstein D, Durkalski V, Conwit R, Neurological Emergency Treatment Trial (NETT) investigators. RAMPART (Rapid Anticonvulsant Medication Prior to Arrival Trial): a double-blind randomized clinical trial of the efficacy of intramuscular midazolam versus intravenous lorazepam in the prehospital treatment of status epilepticus by paramedics. Epilepsia 2011; 5: 45-7.
    • (2011) Epilepsia , vol.5 , pp. 45-47
    • Silbergleit, R.1    Lowenstein, D.2    Durkalski, V.3    Conwit, R.4
  • 44
    • 84857132739 scopus 로고    scopus 로고
    • Intramuscular versus intravenous therapy for prehospital status epilepticus
    • Silbergleit R, Durkalski V, Lowenstein D, et al. Intramuscular versus intravenous therapy for prehospital status epilepticus. N Engl J Med 2012; 366: 591-600.
    • (2012) N Engl J Med , vol.366 , pp. 591-600
    • Silbergleit, R.1    Durkalski, V.2    Lowenstein, D.3
  • 45
    • 75349104992 scopus 로고    scopus 로고
    • Lorazepam versus diazepam-phenytoin combination in the treatment of convulsive status epilepticus in children: A randomized controlled trial
    • Sreenath TG, Gupta P, Sharma KK, Krishnamurthy S. Lorazepam versus diazepam-phenytoin combination in the treatment of convulsive status epilepticus in children: a randomized controlled trial. Eur J Paediatr Neurol 2010; 14: 162-8.
    • (2010) Eur J Paediatr Neurol , vol.14 , pp. 162-168
    • Sreenath, T.G.1    Gupta, P.2    Sharma, K.K.3    Krishnamurthy, S.4
  • 46
    • 70350180759 scopus 로고    scopus 로고
    • Efficacy of buccal midazolam compared to intravenous diazepam in controlling convulsions in children: A randomized controlled trial
    • Talukdar B, Chakrabarty B. Efficacy of buccal midazolam compared to intravenous diazepam in controlling convulsions in children: a randomized controlled trial. Brain Dev 2009; 31: 744-9.
    • (2009) Brain Dev , vol.31 , pp. 744-749
    • Talukdar, B.1    Chakrabarty, B.2
  • 47
    • 0032541616 scopus 로고    scopus 로고
    • A comparison of four treatments for generalized convulsive status epilepticus
    • Veterans Affairs Status Epilepticus Cooperative Study Group
    • Treiman DM, Meyers PD, Walton NY, et al. A comparison of four treatments for generalized convulsive status epilepticus. Veterans Affairs Status Epilepticus Cooperative Study Group. N Engl J Med 1998; 339: 792-8.
    • (1998) N Engl J Med , vol.339 , pp. 792-798
    • Treiman, D.M.1    Meyers, P.D.2    Walton, N.Y.3
  • 48
    • 77953839730 scopus 로고    scopus 로고
    • What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam?
    • Trinka E. What is the relative value of the standard anticonvulsants: phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam? Epilepsia 2009; 50: 40-3.
    • (2009) Epilepsia , vol.50 , pp. 40-43
    • Trinka, E.1
  • 49
    • 0014298209 scopus 로고
    • Intravenous diphenylhydantoin in treatment of acute repetitive seizures
    • Wallis W, Kutt H, McDowell F. Intravenous diphenylhydantoin in treatment of acute repetitive seizures. Neurology 1968; 18: 513-25.
    • (1968) Neurology , vol.18 , pp. 513-525
    • Wallis, W.1    Kutt, H.2    McDowell, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.