Syntaxin4 interacting protein (Synip) binds phosphatidylinositol (3,4,5) triphosphate

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Saito, Tsugumichi ^a   Okada, Shuichi ^a   Nohara, Atsushi ^a   Tagaya, Yuko ^a   Osaki, Aya ^a   Oh i, Shinsuke ^a   Takahashi, Hiroki ^a   Tsuchiya, Takafumi ^a   Hashimoto, Koshi ^a   Satoh, Tetsurou ^a   Yamada, Masanobu ^a   Pessin, Jeffrey E ^b   Mori, Masatomo ^a  

^a GUNMA UNIVERSITY   (Japan)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 4; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHATIDYLINOSITOL 3,4 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; SYNTAXIN 4;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL FRACTIONATION; CELL MEMBRANE; CONTROLLED STUDY; DISSOCIATION; ENZYME LOCALIZATION; ENZYME SUBSTRATE COMPLEX; IN VITRO STUDY; INSULIN RESPONSE; NONHUMAN; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

3T3-L1 CELLS; ANIMALS; CELL MEMBRANE; GLUCOSE TRANSPORTER TYPE 4; INSULIN; MICE; MUTANT PROTEINS; PHOSPHATIDYLINOSITOL PHOSPHATES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; QA-SNARE PROTEINS; VESICULAR TRANSPORT PROTEINS;

EID: 84864534029     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042782     Document Type: Article

References (25)

1. White MF, Kahn CR, (1994) The insulin signaling system. J Biol Chem 269: 1-4.
2. Siddle K, (1992) The insulin receptor and type 1 IGF receptor: comparison of structure and function. Prog Gowth Factor Res 4: 301-320.
3. Watson RT, Pessin JE, (2001) Subcellular compartmentalization and trafficking of the insulin-responsive glucose transporter, GLUT4. Exp Cell Res 271: 75-83.
4. Farese RV, Sajan MP, Standaert ML, (2005) Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): Actions and defects in obesity and type II diabetes. Exp Biol Med 230: 593-605.
5. Bandyopahyay G, Standaert ML, Galloway L, Moscat J, Farese RV, (1997) Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology 138: 4721-4731.
6. Calera MR, Martinez C, Liu H, Jack AK, Birnbaum MJ, et al. (1998) Insulin increases the association of Akt-2 with Glut4-containing vesicles. J Biol Chem 273: 7201-7204.
7. Manna P, Jain SK, (2011) Hydrogen sulfide and L-Cysteine increase phosphatidylinositol 3,4,5-triphosphate (PIP3) and glucose utilization by inhibiting phosphatase and tensin homolog (PTEN) protein and activating phosphoinositide 3-kinase (PI3K)/serine/threonine protein kinase (AKT)/protein kinase Cζ/λ (PKCζ/λ) in 3T3l1 adipocytes. J Biol Chem 286: 39848-39859.
8. Lauritzen HP, Ploug T, Ai H, Donsmark M, Prats C, et al. (2008) Denervation and high-fat diet reduce insulin signaling in T-tubules in skeletal muscle of living mice. Diabetes 57: 13-23.
9. Min J, Okada S, Kanzaki M, Elmendorf JS, Coker KJ, et al. (1999) Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. Mol Cell 3: 751-760.
10. Yamada E, Okada S, Saito T, Ohshima K, Sato M, et al. (2005) Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles. J Cell Biol 168: 921-928.
11. Saito T, Okada S, Yamada E, Ohshima K, Shimizu H, et al. (2003) Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cell. J Biol Chem 278: 36718-36725.
12. Vicogne J, Vollenweider D, Smith JR, Huang P, Frohman MA, et al. (2006) Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion. Proc Natl Acad Sci USA 103: 14761-14766.
13. Macias MJ, Hyvönen M, Baraldi E, Schultz J, Sudol M, et al. (1996) Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide. Nature 382: 646-649.
14. Lu PJ, Zhou XZ, Shen M, Lu KP, (1999) Function of WW domains as phosphoserine- or phosphothreonine-binding modules. Science 283: 1325-1328.
15. Ilsley JL, Sudol M, Winder SJ, (2002) The WW domain: Linking cell signaling to the membrane cytoskeleton. Cell Signal 14: 183-189.
16. Waters SB, Yamauchi K, Pessin JE, (1995) Insulin-stimulated disassociation of the SOS-Grb2 complex. Mol Cell Biol 15: 2791-2799.
17. Okada S, Mori M, Pessin JE, (2003) Introduction of DNA into 3T3-L1 adipocytes by electraporation. Methods Mol Med 83: 93-96.
18. Kandror KV, Stephens JM, Pilch PF, (1995) Expression and compartmentalization of caveolin in adipose cells: coordinate regulation with and structural segregation from GLUT4. J Cell Biol 129: 999-1006.
19. Farese RV, Farese RV Jr, Sabir MA, Larson RE, Trudeau WL 3rd, et al. (1984) The mechanism of action of insulin on phospholipid metabolism in rat adipose tissue. Requirement for protein synthesis and a carbohydrate source, and relationship to activation of pyruvate dehydrogenase. Diabetes 33: 648-655.
20. Sandra A, Fyler DJ, (1982) The effect of membrane phospholipid modification on insulin action in adipocytes from normal and streptozotocin-induced diabetic rats. Horm Metab Res 14: 638-641.
21. Sandra A, Fyler DJ, Marshall SJ, (1985) Phospholipid-induced inhibition of insulin-stimulated glucose transport in isolated adipocytes: Interactions of phospholipids with inhibitors of glucose transport and insulinmimetic agents. Endocr Res 11: 95-111.
22. He J, Haeney RM, Vora M, Verkhusha VV, Stahelin RV, et al. (2008) Molecular mechanism of membrane targeting by the GRP1 PH domain. J Lipid Res 49: 1807-1815.
23. Shisheva A, (2008) Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns (3,4,5)P3. Am J Physiol Endocrinol Metab 295: E536-544.
24. Lu PJ, Zhou XZ, Liou YC, Noel JP, Lu KP, (2002) Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function. J Biol Chem 277: 2381-2384.
25. Hu H, Columbus J, Zhang Y, Wu D, Lian L, et al. (2004) A map of WW domain family interactions. Proteomics 4: 643-655.