Using Stochastic modelling to identify unusual continuous glucose monitor measurements and behaviour, in newborn infants

BioMedical Engineering Online

Volumn 11, Issue , 2012, Pages

  Signal, Matthew ^a,d   Le Compte, Aaron ^a,d   Harris, Deborah L ^b,c   Weston, Phil J ^c   Harding, Jane E ^b,d   Chase, Geoff ^d   Alsweiler, Jane ^d   Harris, Deborah ^d   Thompson, Ben ^d   Wouldes, Trecia ^d   Ansell, Judith ^d   Anstice, Nicola ^d   Arthur, Jo ^d   Bevan, Coila ^d   Bluett, Kate ^d   Campbell, Ellen ^d   Chakraborty, Arijit ^d   Crawford, Tineke ^d   Frost, Karen ^d   Gamble, Greg ^d   Jacobs, Rob ^d   Jones, Kelly ^d   Martin, Sapphire ^d   Matheson, Gill ^d   McKnight, Grace ^d   McQuoid, Christina ^d   Paynter, Janine ^d   Rogers, Jenny ^d   Stewart, Heather ^d   Timmings, Anna ^d   Young, Rebecca ^d   Yu, Sandy ^d   more..

^a UNIVERSITY OF CANTERBURY   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c WAIKATO DISTRICT HEALTH BOARD   (New Zealand)

^d NONE

Author keywords

Classify; Continuous Glucose Monitor; Glycaemia; Intensive care unit; Neonatal

Indexed keywords

DIAGNOSIS; ECONOMIC AND SOCIAL EFFECTS; GLUCOSE; INTENSIVE CARE UNITS; PHYSIOLOGICAL MODELS; RISK ASSESSMENT; STOCHASTIC SYSTEMS;

CLASSIFICATION METHODS; CLASSIFY; CONFIDENCE INTERVAL; CONTINUOUS GLUCOSEMONITORING (CGM); DETECTION AND DIAGNOSIS; GLUCOSE MONITORS; GLYCAEMIA; NEONATAL;

STOCHASTIC MODELS;

ARTICLE; BLOOD; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; MALE; METHODOLOGY; NEWBORN; PHYSIOLOGIC MONITORING; REPRODUCIBILITY; RETROSPECTIVE STUDY; RISK; STATISTICAL ANALYSIS; STATISTICAL MODEL; STATISTICS;

BLOOD GLUCOSE; DATA INTERPRETATION, STATISTICAL; FEMALE; HUMANS; HYPOGLYCEMIA; INFANT, NEWBORN; MALE; MODELS, STATISTICAL; MONITORING, PHYSIOLOGIC; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; RISK; STOCHASTIC PROCESSES;

EID: 84864519217     PISSN: None     EISSN: 1475925X     Source Type: Journal    
DOI: 10.1186/1475-925X-11-45     Document Type: Article

References (31)

1. Capes SE, Hunt D, Malmberg K, Gerstein HC. Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview. Lancet 2000, 355:773-778. 10.1016/S0140-6736(99)08415-9, 10711923.
2. Finney SJ, Zekveld C, Elia A, Evans TW. Glucose control and mortality in critically ill patients. JAMA: the journal of the American Medical Association 2003, 290:2041-2047.
3. Krinsley JS. Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients. Mayo Clinic proceedings Mayo Clinic 2003, 78:1471-1478.
4. McCowen KC, Malhotra A, Bistrian BR. Stress-induced hyperglycemia. Crit Care Clin 2001, 17:107-124. 10.1016/S0749-0704(05)70154-8, 11219223.
5. Mizock BA. Alterations in fuel metabolism in critical illness: hyperglycaemia. Best Pract Res Clin Endocrinol Metab 2001, 15:533-551. 10.1053/beem.2001.0168, 11800522.
6. Umpierrez GE, Isaacs SD, Bazargan N, You X, Thaler LM, Kitabchi AE. Hyperglycemia: an independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metab 2002, 87:978-982. 10.1210/jc.87.3.978, 11889147.
7. Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001, 345:1359-1367. 10.1056/NEJMoa011300, 11794168.
8. Bistrian BR. Hyperglycemia and infection: which is the chicken and which is the egg?. JPEN J Parenter Enteral Nutr 2001, 25:180-181. 10.1177/0148607101025004180, 11434647.
9. Beardsall K, Vanhaesebrouck S, Ogilvy-Stuart AL, Vanhole C, Palmer CR, van Weissenbruch M, Midgley P, Thompson M, Thio M, Cornette L, et al. Early Insulin Therapy in Very-Low-Birth-Weight Infants. N Engl J Med 2008, 359:1873-1884. 10.1056/NEJMoa0803725, 18971490.
10. Le Compte A, Chase J, Lynn A, Hann C, Shaw G, Wong X, Lin J. Blood Glucose Controller for Neonatal Intensive Care: Virtual trials development and 1st clinical trials. Journal of Diabetes Science and Technology 2009, 3:1066-1081. 2769904, 20144420.
11. Egi M, Bellomo R, Stachowski E, French CJ, Hart G. Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology 2006, 105:244-252. 10.1097/00000542-200608000-00006, 16871057.
12. Egi M, Bellomo R, Stachowski E, French CJ, Hart GK, Taori G, Hegarty C, Bailey M. Hypoglycemia and outcome in critically ill patients. Mayo Clinic proceedings Mayo Clinic 2010, 85:217-224. 2843109, 20176928.
13. Hermanides J, Bosman RJ, Vriesendorp TM, Dotsch R, Rosendaal FR, Zandstra DF, Hoekstra JB, DeVries JH. Hypoglycemia is associated with intensive care unit mortality. Crit Care Med 2010, 38:1430-1434. 10.1097/CCM.0b013e3181de562c, 20386307.
14. Krinsley JS. Glycemic variability: a strong independent predictor of mortality in critically ill patients. Crit Care Med 2008, 36:3008-3013. 10.1097/CCM.0b013e31818b38d2, 18824908.
15. Carayon P, Gurses AP. A human factors engineering conceptual framework of nursing workload and patient safety in intensive care units. Intensive Crit Care Nurs 2005, 21:284-301. 10.1016/j.iccn.2004.12.003, 16182125.
16. Chase JG, Andreassen S, Jensen K, Shaw GM. Impact of Human Factors on Clinical Protocol Performance: A Proposed Assessment Framework and Case Examples. Journal of Diabetes Science and Technology 2008, 2:409-416. 2769730, 19885205.
17. Mackenzie I, Ingle S, Zaidi S, Buczaski S. Tight glycaemic control: a survey of intensive care practice in large English hospitals. Intensive Care Med 2005, 31:1136. 10.1007/s00134-005-2677-2, 16052274.
18. Goldberg PA, Siegel MD, Russell RR, Sherwin RS, Halickman JI, Cooper DA, Dziura JD, Inzucchi SE. Experience with the continuous glucose monitoring system in a medical intensive care unit. Diabetes Technol Ther 2004, 6:339-347. 10.1089/152091504774198034, 15198837.
19. Brunner R, Kitzberger R, Miehsler W, Herkner H, Madl C, Holzinger U. Accuracy and reliability of a subcutaneous continuous glucose-monitoring system in critically ill patients. Crit Care Med 2011, 39:659-664. 10.1097/CCM.0b013e318206bf2e, 21221002.
20. Lorencio C, Leal Y, Bonet A, Bondia J, Palerm CC, Tache A, Sirvent JM, Vehi J. Real-Time Continuous Glucose Monitoring in an Intensive Care Unit: Better Accuracy in Patients with Septic Shock. Diabetes Technol Ther 2012, 14:568-575.
21. De Block C, Manuel YKB, Van Gaal L, Rogiers P. Intensive insulin therapy in the intensive care unit: assessment by continuous glucose monitoring. Diabetes Care 2006, 29:1750-1756. 10.2337/dc05-2353, 16873775.
22. Breton M, Kovatchev B. Analysis, modeling, and simulation of the accuracy of continuous glucose sensors. J Diabetes Sci Technol 2008, 2:853-862. 2740661,2740661, 19750186.
23. Klonoff DC. Continuous Glucose Monitoring: Roadmap for 21st century diabetes therapy. Diabetes Care 2005, 28:1231-1239. 10.2337/diacare.28.5.1231, 15855600.
24. Klonoff DC. A review of continuous glucose monitoring technology. Diabetes Technol Ther 2005, 7:770-775. 10.1089/dia.2005.7.770, 16447333.
25. Chee F, Fernando T, van Heerden PV. Closed-loop glucose control in critically ill patients using continuous glucose monitoring system (CGMS) in real time. IEEE Trans Inf Technol Biomed 2003, 7:43-53. 10.1109/TITB.2003.808509, 12670018.
26. Chee F, Fernando TL, Savkin AV, van Heeden V. Expert PID control system for blood glucose control in critically ill patients. IEEE Trans Inf Technol Biomed 2003, 7:419-425. 10.1109/TITB.2003.821326, 15000368.
27. Clarke WL, Anderson S, Farhy L, Breton M, Gonder-Frederick L, Cox D, Kovatchev B. Evaluating the clinical accuracy of two continuous glucose sensors using continuous glucose-error grid analysis. Diabetes Care 2005, 28:2412-2417. 10.2337/diacare.28.10.2412, 16186272.
28. Skyler JS. Continuous glucose monitoring: an overview of its development. Diabetes Technol Ther 2009, 11(Suppl 1):S5-10.
29. Cembrowski GS, Tran DV, Higgins TN. The use of serial patient blood gas, electrolyte and glucose results to derive biologic variation: a new tool to assess the acceptability of intensive care unit testing. Clinical chemistry and laboratory medicine : CCLM / FESCC 2010, 48:1447-1454.
30. Watkinson PJ, Barber VS, Amira E, James T, Taylor R, Young JD. The effects of precision, haematocrit, pH and oxygen tension on point-of-care glucose measurement in critically ill patients: a prospective study. Ann Clin Biochem 2012, 49:144-151. 10.1258/acb.2011.011162, 22349553.
31. Lin J, Lee D, Chase JG, Shaw GM, Le Compte A, Lotz T, Wong J, Lonergan T, Hann CE. Stochastic modelling of insulin sensitivity and adaptive glycemic control for critical care. Comput Meth Prog Bio 2008, 89:141-152.