Is the carotid intima-media thickness really a good surrogate marker of atherosclerosis?

Journal of Atherosclerosis and Thrombosis

Volumn 19, Issue 7, 2012, Pages 680-690

  Tran, Loan Thi Thanh ^a   Park, Hye Jin ^b   Kim, Ho dirk ^a  

^a Sungkyunkwan University   (South Korea)

^b National Forensic Service   (South Korea)

Author keywords

Carotid atherosclerosis; Collagen; Elastin; Morphometry; Serum lipids

Indexed keywords

COLLAGEN; ELASTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ARTERIAL WALL THICKNESS; ARTICLE; CAROTID ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY CALCIFICATION; CORONARY ARTERY OBSTRUCTION; DISEASE MARKER; HISTOPATHOLOGY; HUMAN; KOREA; MAJOR CLINICAL STUDY; MALE; MORPHOMETRICS; QUANTITATIVE ANALYSIS; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGED; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; CAROTID INTIMA-MEDIA THICKNESS; CHOLESTEROL; CHOLESTEROL, LDL; COLLAGEN; ELASTIN; HUMANS; LIPIDS; MALE; MIDDLE AGED; RISK FACTORS; TRIGLYCERIDES; YOUNG ADULT;

EID: 84864505091     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.11767     Document Type: Article

References (42)

1. Costanzo P, Perrone-Filardi P, Vassallo E, Paolillo S, Cesa-rano P, Brevetti G, Chiariello M: Does carotid intima-media thickness regression predict reduction of cardiovascular events? A meta-analysis of 41 randomized trials. J Am Coll Cardiol, 2010; 56: 2006-2020
2. Bernetti M, Abbate R, Cerini G, Gensini G F, Poggesi L, Boddi M: Carotid and femoral intima-media thickness as an early atherosclerotic marker. Advantages and limits. G Ital Cardiol, 2011; 12: 72-81
3. Rodriguez-Macias KA, Lind L, Naessen T: Thicker carotid intima layer and thinner media layer in subjects with cardiovascular diseases. An investigation using noninvasive high-frequency ultrasound. Atherosclerosis, 2006; 189: 393-400
4. Vicenzini E, Ricciardi MC, Puccinelli F, Altieri M, Vana-core N, Di Piero V, Lenzi GL: Common carotid artery intima-media thickness determinants in a population study. J Ultrasound Med, 2007; 26: 427-432; 434
5. Eigenbrodt ML, Bursac Z, Tracy RE, Mehta JL, Rose KM, Couper DJ: B-mode ultrasound common carotid artery intima-media thickness and external diameter: cross-sectional and longitudinal associations with carotid atherosclerosis in a large population sample. Cardiovasc Ultrasound, 2008; 6: 10
6. Katsuda S, Kaji T: Atherosclerosis and extracellular matrix. J Atheroscler Thromb, 2003; 10: 267-274
7. Goncalves I, Moses J, Dias N, Pedro LM, Fernandes e Fernandes J, Nilsson J, Ares MP: Changes related to age and cerebrovascular symptoms in the extracellular matrix of human carotid plaques. Stroke, 2003; 34: 616-622
8. Bobryshev YV: Calcification of elastic fibers in human atherosclerotic plaque. Atherosclerosis, 2005; 180: 293-303
9. Nadkarni SK, Bouma BE, de Boer J, Tearney GJ: Evaluation of collagen in atherosclerotic plaques: the use of two coherent laser-based imaging methods. Lasers Med Sci, 2009; 24: 439-445
10. Akima T, Nakanishi K, Suzuki K, Katayama M, Ohsuzu F, Kawai T: Soluble elastin decreases in the progress of atheroma formation in human aorta. Circ J, 2009; 73: 2154-2162
11. Seo JS, Lee SY, Kim HD: Quantitative analysis of aortic atherosclerosis in Korean female: a necropsy study. J Korean Med Sci, 2007; 22: 536-545
12. Goldstein JA, Gallagher MJ, O'Neill WW, Ross MA, O'Neil BJ, Raff GL: A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain. J Am Coll Cardiol, 2007; 49: 863-871
13. Stary HC: Natural History and Histological Classification of Atherosclerotic Lesions: An Update. Arterioscler Thromb Vasc Biol, 2000; 20: 1177-1178
14. Virmani R, Kolodgie FD, Burke A P, Farb A, Schwartz SM: Lessons From Sudden Coronary Death: A Comprehensive Morphological Classification Scheme for Atherosclerotic Lesions. Arterioscler Thromb Vasc Biol, 2000; 20: 1262-1275
15. Roman MJ, Moeller E, Davis A, Paget SA, Crow MK, Lockshin MD, Sammaritano L, Devereux RB, Schwartz JE, Levine DM, Salmon JE: Preclinical carotid atherosclerosis in patients with rheumatoid arthritis. Ann Intern Med, 2006; 144: 249-256
16. Stein JH, Korcarz CE, Hurst RT, Lonn E, Kendall CB, Mohler ER, Najjar SS, Rembold CM, Post WS: Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine. J Am Soc Echocar-diogr, 2008; 21: 93-111; 189-190
17. Finn AV, Kolodgie FD, Virmani R: Correlation between carotid intimal/medial thickness and atherosclerosis: a point of view from pathology. Arterioscler Thromb Vasc Biol, 2010; 30: 177-181
18. Inaba Y, Chen JA, Bergmann SR: Carotid plaque, compared with carotid intima-media thickness, more accurately predicts coronary artery disease events: A meta-analysis. Atherosclerosis, 2012; 220: 128-133
19. Wang PW, Liou CW, Wang ST, Eng HL, Liu RT, Tung SC, Chien WY, Lu YC, Kuo MC, Hsieh CJ, Chen CH, Chen J F, Chu JW, Reaven GM: Relative impact of low-density lipoprotein-cholesterol concentration and insulin resistance on carotid wall thickening in nondiabetic, nor-motensive volunteers. Metabolism, 2002; 51: 255-259
20. Kastelein JJ, Akdim F, Stroes ES, Zwinderman AH, Bots ML, Stalenhoef A F, Visseren FL, Sijbrands EJ, Trip MD, Stein EA, Gaudet D, Duivenvoorden R, Veltri E P, Marais AD, de Groot E: Simvastatin with or without ezetimibe in familial hypercholesterolemia. N Engl J Med, 2008; 358: 1431-1443
21. Fleg JL, Mete M, Howard BV, Umans JG, Roman MJ, Ratner RE, Silverman A, Galloway JM, Henderson JA, Weir MR, Wilson C, Stylianou M, Howard WJ: Effect of statins alone versus statins plus ezetimibe on carotid atherosclerosis in type 2 diabetes: the SANDS (Stop Atherosclerosis in Native Diabetics Study) trial. J Am Coll Car-diol, 2008; 52: 2198-2205
22. Magyar MT, Paragh G, Katona E, Valikovics A, Seres I, Csiba L, Bereczki D: Serum cholesterols have a more important role than triglycerides in determining intima-media thickness of the common carotid artery in subjects younger than 55 years of age. J Ultrasound Med, 2004; 23: 1161-1169
23. Amato M, Montorsi P, Ravani A, Oldani E, Galli S, Rav-agnani PM, Tremoli E, Baldassarre D: Carotid intima-media thickness by B-mode ultrasound as surrogate of coronary atherosclerosis: correlation with quantitative coronary angiography and coronary intravascular ultrasound findings. Eur Heart J, 2007; 28: 2094-2101
24. Prati P, Tosetto A, Vanuzzo D, Bader G, Casaroli M, Can-ciani L, Castellani S, Touboul PJ: Carotid intima media thickness and plaques can predict the occurrence of isch-emic cerebrovascular events. Stroke, 2008; 39: 2470-2476
25. Virmani R, Burke A P, Farb A, Kolodgie FD: Pathology of the vulnerable plaque. J Am Coll Cardiol, 2006; 47: 13-18
26. Spence JD: Technology Insight: ultrasound measurement of carotid plaque--patient management, genetic research, and therapy evaluation. Nat Clin Pract Neurol, 2006; 2: 611-619
27. Kolodgie FD, Burke A P, Nakazawa G, Virmani R: Is pathologic intimal thickening the key to understanding early plaque progression in human atherosclerotic disease? Arterioscler Thromb Vasc Biol, 2007; 27: 986-989
28. Hector EE, Robins S P, Mercer DK, Brittenden J, Wain-wright CL: Quantitative measurement of mature collagen cross-links in human carotid artery plaques. Atherosclerosis, 2010; 211: 471-474
29. Rekhter MD: Collagen synthesis in atherosclerosis: too much and not enough. Cardiovasc Res, 1999; 41: 376-384
30. Goncalves I, Lindholm MW, Pedro LM, Dias N, Fernandes e Fernandes J, Fredrikson GN, Nilsson J, Moses J, Ares MP: Elastin and calcium rather than collagen or lipid content are associated with echogenicity of human carotid plaques. Stroke, 2004; 35: 2795-2800
31. Barnes MJ, Farndale RW: Collagens and atherosclerosis. Exp Gerontol, 1999; 34: 513-525
32. Seyama Y, Wachi H: Atherosclerosis and matrix dystrophy. J Atheroscler Thromb, 2004; 11: 236-245
33. Tzou WS, Douglas PS, Srinivasan SR, Bond MG, Tang R, Li S, Chen W, Berenson GS, Stein JH: Distribution and predictors of carotid intima-media thickness in young adults. Prev Cardiol, 2007; 10: 181-189
34. Wechsler LR, Kistler J P, Davis KR, Kaminski MJ: The prognosis of carotid siphon stenosis. Stroke, 1986; 17: 714-718
35. Rubba P, Panico S, Bond MG, Covetti G, Celentano E, Iannuzzi A, Galasso R, Belisario MA, Pastinese A, Sac-chetti L, Mancini M, Salvatore F: Site-specific atherosclerotic plaques in the carotid arteries of middle-aged women from southern Italy: associations with traditional risk factors and oxidation markers. Stroke, 2001; 32: 1953-1959
36. Polak J F, Person SD, Wei GS, Godreau A, Jacobs DR Jr, Harrington A, Sidney S, O'Leary DH: Segment-specific associations of carotid intima-media thickness with cardiovascular risk factors: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Stroke, 2010; 41: 9-15
37. Zhang F, Barker AJ, Gates PE, Strain WD, Fulford J, Mazzaro L, Shore AC, Bellenger NG, Lanning C, Shan-das R: Noninvasive wall shear stress measurements in human carotid artery using echo particle image velocime-try: Initial clinical studies. Ultrasonics Symposium (IUS), 2009 IEEE International, 2009; 562-565
38. Gnasso A, Carallo C, Irace C, Spagnuolo V, De Novara G, Mattioli PL, Pujia A: Association between intima-media thickness and wall shear stress in common carotid arteries in healthy male subjects. Circulation, 1996; 94: 3257-3262
39. Irace C, Cortese C, Fiaschi E, Carallo C, Farinaro E, Gnasso A: Wall shear stress is associated with intima-media thickness and carotid atherosclerosis in subjects at low coronary heart disease risk. Stroke, 2004; 35: 464-468
40. Augst AD, Ariff B, Mc GTSA, Xu XY, Hughes AD: Analysis of complex flow and the relationship between blood pressure, wall shear stress, and intima-media thickness in the human carotid artery. Am J Physiol Heart Circ Physiol, 2007; 293: 1031-1037
41. Franceschi C, Bonafe M, Valensin S, Olivieri F, De Luca M, Ottaviani E, De Benedictis G: Inflamm-aging. An evolutionary perspective on immunosenescence. Ann N Y Acad Sci, 2000; 908: 244-254
42. Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA, Csiszar A, Ikeno Y, Le Couteur D, Elliott PJ, Becker KG, Navas P, Ingram DK, Wolf NS, Ungvari Z, Sinclair DA, de Cabo R: Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab, 2008; 8: 157-168