Sort-synchronization control in microuidic loop devices with experimental uncertainties using a model predictive control (MPC) framework

IFAC Proceedings Volumes (IFAC-PapersOnline)

Volumn 18, Issue PART 1, 2011, Pages 4886-4891

  Maddala, Jeevan ^a   Vanapalli, Siva A ^a   Rengaswamy, Raghunathan ^a  

^a Texas Tech University   (United States)

Author keywords

Active control; Loop device; Microuidics; Model predictive control; Optimization; Sort synchronization

Indexed keywords

DROPS; OPTIMIZATION; PREDICTIVE CONTROL SYSTEMS; SYNCHRONIZATION;

ACTIVE CONTROL; BIFURCATIONS AND CHAOS; EXPERIMENTAL UNCERTAINTY; LOOP DEVICE; MICROUIDICS; MODEL BASED CONTROL ALGORITHMS; NONLINEAR BEHAVIOR; SYNCHRONIZATION CONTROL;

MODEL PREDICTIVE CONTROL;

EID: 84864504363     PISSN: 14746670     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.3182/20110828-6-IT-1002.03342     Document Type: Conference Paper

References (17)

1. Abate, A.R. and Weitz, D.A. (2008). Single-layer membrane valves for elastomeric microuidic devices. Applied Physics Letters., 92, 243509(1)- 243509(3).
2. Abate, A.R., Agresti, J.J., and Weitz, D.A. (2010). Microuidic sorting with high-speed single layer membrane valves. Applied Physics Letters., 96, 203509(1)- 203509(3).
3. Bhattacharjee, B. and Najjaran, H. (2010). Droplet position control in digital microuidic systems. Biomed Microdevices, 12, 115-124.
4. Brouzes, E., Medkova, M., Savenelli, N., Marran, D., twardowski, M., Hutchison, J.B., Rothberg, J.M., Link, D.R., Perrimon, N., and Samuels, M.L. (2009). Droplet microuidic technology for single-cell high throughput screening. PNAS, 106, 14195-14200.
5. Cristobal, G., Benoit, J.P., Jaonicot, M., and Ajdari, A. (2006). Microuidic bypass for efficient passive regulation of droplet traffic at a junction. Applied Physics Letters., 89, 034104(1)-034104(3).
6. Fuerstman, M.J., Garstecki, P., and Whitesides, G.M. (2007). Coding/decoding and reversibility of droplet trains in microuidic networks. Science, 315, 828-832.
7. Haeberle, S. and Zengerle III, R. (2007). Microuidic platforms for lab-on-chip applications. Lab Chip., 7, 1094-1110.
8. Huebner, A., Srisa-Art, M., Holt, D., Abell, C., Hollfelder, F., deMello, A.J., and Edel, J.B. (2007). Quantitative detection od protein expression in single cells using droplet micruidics. Chem. Commun., 1218-1220.
9. Jin, B.J., Kim, Y.W., Lee, Y., and Yoo, J.Y. (2010). Droplet merging in a straight microchannel using droplet size or viscosity difference. J. Micromech Mi- croeng, 20, 035003(1)-035003(3).
10. Jousse, F., Lian, G., Janes, R., and Melrose, J. (2005). Compact model for multi-phase liquid-liquid ows in microuidic devices. Lab Chip., 5, 646-656.
11. Labrot, V., Schindler, M., Guillot, P., Colin, A., and Joanicot, M. (2009). Extracting the hydrodynamic resistance of droplets from their behavior in microchannel networks. BioMicrouidics., 3, 012804(1)-012804(16).
12. Maddala, J., Srinivasan, B., Bithi, S.S., Vanapalli, S.A., and Rengaswamy, R. (2010). Design of a model-based feedback controller for active sorting and synchronization of droplets in microuidic loop. article submitted to AIChE Journal.
13. Prakash, M. and Gershenfeld, N. (2007). Microuidic bubble logic. Science, 315, 832-835.
14. Schindler, M. and Ajdari, A. (2008). Droplet traffic microuidic networks: A simple model for understanding and designing. Physical Review Letters., 100, 044501(1)- 044501(4).
15. Smith, B.J. and Gaver III, D.P. (2010). Agent-based simulations of complex droplet pattern formation in a two-branch microuidic network. Lab Chip., 10, 303-312.
16. Song, H., Chen, D.L., and Ismagilov, R.F. (2006). Reactions in droplets in microuidic channels. Angew. Chem. Int. Ed., 45, 7336-7356.
17. Zheng, B., Tice, J.D., and Ismagilov, R.F. (2004). Formation of droplets of alternating composition in micruidic channels and applications to indexing of concentrations in droplet based assays. Anal Chem., 76, 4977-4982.