Droplet merging in a straight microchannel using droplet size or viscosity difference

Journal of Micromechanics and Microengineering

Volumn 20, Issue 3, 2010, Pages

  Jin, B J ^a   Kim, Y W ^a   Lee, Y ^b   Yoo, J Y ^a,c  

^a Seoul National University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL TRANSPLANTATION; CHANNEL INTERSECTIONS; CONTINUOUS PHASE; CROSS SECTION; DESYNCHRONIZATION; DIFFERENT SIZES; DISPERSED PHASE; DROPLET SIZES; HIGH PRECISION; MERGING TECHNIQUES; NANOLITERS; NANOPARTICLE SYNTHESIS; PICOLITER DROPLETS; SIDE-CHANNEL; SUDDEN EXPANSION; VELOCITY DIFFERENCE;

MERGING; MICROCHANNELS; PHASE INTERFACES; VISCOSITY;

DROP FORMATION;

EID: 76449086930     PISSN: 09601317     EISSN: 13616439     Source Type: Journal    
DOI: 10.1088/0960-1317/20/3/035003     Document Type: Article

References (35)

1. Hung L-H, Choi K M, Tseng W-Y, Tan Y-C, Shea K J and Lee A P 2006 Alternating droplet generation and controlled dynamic droplet fusion in microfluidic device for CdS nanoparticle synthesis Lab Chip 6 174-8
2. Shintaku H, Kuwabara T, Kawano S, Suzuki T, Kanno I and Kotera H 2007 Micro cell encapsulation and its hydrogel-beads production using microfluidic device Microsyst. Technol. 13 951-8
3. Thorsen T, Roberts R W, Arnold F H and Quake S R 2001 Dynamic pattern formation in a vesicle-generating microfluidic device Phys. Rev. Lett. 86 4163-6
4. Nisisako T, Torii T and Higuchi T 2002 Droplet formation in a microchannel network Lab Chip 2 24-6
5. Anna S L, Bontoux N and Stone H A 2003 Formation of dispersions using 'flow focusing' in microchannels Appl. Phys. Lett. 82 364-6
6. Song H, Tice J D and Ismagilov R F 2003 A microfluidic system for controlling reaction networks in time Angew. Chem. Int. Ed. 42 768-72
7. Wang C, Nguyen N-T and Wong T N 2007 Optical measurement of flow field and concentration field inside a moving nanoliter droplet Sensors Actuators A 133 317-22
8. Tan Y-C, Ho Y L and Lee A P 2007 Droplet coalescence by geometrically mediated flow in microfluidic channels Microfluid Nanofluid 3 495-9
9. Liu K, Ding H, Chen Y and Zhao X-Z 2007 Droplet-based synthetic method using microflow focusing and droplet fusion Microfluid Nanofluid 3 239-43
10. Niu X, Gulati S, Edel J B and deMello A J 2008 Pillar-induced droplet merging in microfluidic circuits Lab Chip 8 1837-41
11. Ahn K, Agresti J, Chong H, Marquez M and Weitz D A 2006 Electrocoalescence of drops synchronized by size-dependent flow in microfluidic channels Appl. Phys. Lett. 88 264105
12. Link D R, Grasland-Mongrain E, Duri A, Sarrazin F, Cheng Z, Cristobal G, Marquez M and Weitz D A 2006 Electric control of droplets in microfluidic devices Angew. Chem. Int. Edn 45 2556-60
13. Lee W, Walker L M and Anna S L 2009 Role of geometry and fluid properties in droplet and thread formation processes in planar flow focusing Phys. Fluids 21 032103
14. Zheng B, Tice J D and Ismagilov R F 2004 Formation of droplets of alternating composition in microfluidic channels and applications to indexing of concentrations in droplet-based assays Anal. Chem. 76 4977-82
15. Okushima S, Nisisako T, Torii T and Higuchi T 2004 Controlled production of monodisperse double emulsions by two-step droplet breakup in microfluidic devices Langmuir 20 9905-8
16. Xia Y and Whitesides G M 1998 Soft lithography Ann. Rev. Mater. Sci. 28 153-84 (Pubitemid 128631417)
17. Patel P N, Smith C K and Patrick C W 2005 Rheological and recovery properties of poly(ethylene glycol) diacrylate hydrogels and human adipose tissue J. Biomed. Mater. Res. A 73 313-9
18. Bremond N, Thiam A R and Bibette J 2008 Decompressing emulsion droplets favors coalescence Phys. Rev. Lett. 100 024501
19. Shankar P N and Kumar M 1994 Experimental-determination of the kinematic viscosity of glycerol-water mixtures Proc. R. Soc. A 444 573-81
20. Antonow G N 1907 Sur la tension superficielle a la limite de deux couches J. Chem. Phys. 5 372-84
21. Lyklema J, Fleer G J and van Leeuwen H P 2000 Fundamentals of Interface and Colloid Science: Liquid-Fluid Interfaces (London: Academic) pp 122-3
22. Limpanuphap S and Derby B 2002 Manufacture of biomaterials by a novel printing process J. Mater. Sci., Mater. Med. 13 1163-6
23. Garstecki P, Fuerstman M J, Stone H A and Whitesides G M 2006 Formation of droplets and bubbles in a microfluidic T-junctionscaling and mechanism of break-up Lab Chip 6 437-46
24. Garstecki P, Gitlin I, DiLuzio W, Whitesides G M, Kumacheva E and Stone H A 2004 Formation of monodisperse bubbles in a microfluidic flow-focusing device Appl. Phys. Lett. 85 2649-51
25. Raven J-P, Marmottant P and Graner F 2006 Dry microfoams: formation and flow in a confined channel Eur. Phys. J. B 51 137-43
26. Seo M, Paquet C, Nie Z, Xu S and Kumacheva E 2007 Microfluidic consecutive flow-focusing droplet generators Soft Matter 3 986-92
27. Hashimoto M, Garstecki P and Whitesides G M 2007 Synthesis of composite emulsions and complex foams with the use of microfluidic flow-focusing devices Small 3 1792-802
28. Fairbrother F and Stubbs A E 1935 Studies in electro-endosmosis: part VI. The 'bubble-tube' method of measurement J. Chem. Soc. 1 527-9
29. Bretherton F P 1961 The motion of long bubbles in tubes J. Fluid Mech. 10 166-88
30. Hetsroni G, Haber S and Wacholder E 1970 The flow fields in and around a droplet moving axially within a tube J. Fluid Mech. 41 689-705
31. Urbant P, Leshansky A and Halupovich Y 2008 On the forced convective heat transport in a droplet-laden flow in microchannels Microfluid Nanofluid 4 533-42
32. Menech M D 2006 Modeling of droplet breakup in a microfluidic T-shaped junction with a phase-field model Phys. Rev. E 73 031505
33. van Steijn V, Kreutzer M T and Kleijn C R 2008 Velocity fluctuations of segmented flow in microchannels Chem. Eng. J. 135S S159-65
34. Beer N R, Rose K A and Kennedy I M 2009 Observed velocity fluctuations in monodisperse droplet generators Lab Chip 9 838-40
35. Levin M H, Fuente de la R and Verkman A S 2007 Urearetics: a small molecule screen yields nanomolar potency inhibitors of urea transporter UT-B FASEB J. 21 551-63