Human milk oligosaccharides reduce Entamoeba histolytica attachment and cytotoxicity in vitro

British Journal of Nutrition

Volumn 108, Issue 10, 2012, Pages 1839-1846

  Jantscher Krenn, Evelyn ^a   Lauwaet, Tineke ^b   Bliss, Laura A ^a   Reed, Sharon L ^b   Gillin, Frances D ^b   Bode, Lars ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amoebiasis; Breast milk; Oligosaccharides

Indexed keywords

GALACTOSE OLIGOSACCHARIDE; HUMAN MILK OLIGOSACCHARIDE; LACTOSE; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; BREAST MILK; CELL ADHESION; CELL DESTRUCTION; CELL PROTECTION; CELL STRAIN HT29; COCULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENTAMOEBA HISTOLYTICA; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PARASITE VIABILITY; TROPHOZOITE;

BACTERIAL ADHESION; ENTAMOEBA HISTOLYTICA; EPITHELIAL CELLS; HUMANS; INTESTINAL MUCOSA; LACTOSE; MILK, HUMAN; OLIGOSACCHARIDES;

BACTERIA (MICROORGANISMS); ENTAMOEBA HISTOLYTICA; PROTOZOA;

EID: 84864467142     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114511007392     Document Type: Article

References (31)

1. Pritt BS & Clark CG (2008) Amebiasis. Mayo Clin Proc 83, 1154-1159.
2. Islam A, Stoll BJ, Ljungstrom I, et al. (1988) The prevalence of Entamoeba histolytica in lactating women and in their infants in Bangladesh. Trans R Soc Trop Med Hyg 82, 99-103.
3. Gillin FD, Reiner DS & Wang CS (1983) Human milk kills parasitic intestinal protozoa. Science 221, 1290-1292.
4. Leon-Sicairos N, Lopez-Soto F, Reyes-Lopez M, et al. (2006) Amoebicidal activity of milk, apo-lactoferrin, sIgA and lyso-zyme. Clin Med Res 4, 106-113.
5. Newburg DS, Ruiz-Palacios GM & Morrow AL (2005) Human milk glycans protect infants against enteric pathogens. Annu Rev Nutr 25, 37-58.
6. Kunz C, Rudloff S, Baier W, et al. (2000) Oligosaccharides in human milk: structural, functional, and metabolic aspects. Annu Rev Nutr 20, 699-722.
7. Bode L (2009) Human milk oligosaccharides: prebiotics and beyond. Nutr Rev 67, Suppl. 2, S183-S191.
8. Bode L (2006) Recent advances on structure, metabolism, and function of human milk oligosaccharides. J Nutr 136, 2127-2130.
9. Morrow AL, Ruiz-Palacios GM, Jiang X, et al. (2005) Humanmilk glycans that inhibit pathogen binding protect breastfeeding infants against infectious diarrhea. J Nutr 135, 1304-1307.
10. Saffer LD & Petri WA Jr (1991) Entamoeba histolytica: recognition of alpha-and beta-galactose by the 260-kDa adherence lectin. Exp Parasitol 72, 106-108.
11. Saffer LD & Petri WA Jr (1991) Role of the galactose lectin of Entamoeba histolytica in adherence-dependent killing of mammalian cells. Infect Immun 59, 4681-4683.
12. Cano-Mancera R & Lopez-Revilla R (1987) Inhibition of the adhesion of Entamoeba histolytica trophozoites to human erythrocytes by carbohydrates. Parasitol Res 74, 18-22.
13. Moro G, Minoli I, Mosca M, et al. (2002) Dosage-related bifidogenic effects of galacto-and fructooligosaccharides in formula-fed term infants. J Pediatr Gastroenterol Nutr 34, 291-295.
14. Boehm G, Fanaro S, Jelinek J, et al. (2003) Prebiotic concept for infant nutrition. Acta Paediatr 91, 64-67.
15. Sinclair HR, de Slegte J, Gibson GR, et al. (2009) Galactooli- gosaccharides (GOS) inhibit Vibrio cholerae toxin binding to its GM1 receptor. J Agric Food Chem 57, 3113-3119.
16. Ravdin JI & Guerrant RL (1981) Role of adherence in cyto-pathogenic mechanisms of Entamoeba histolytica. Study with mammalian tissue culture cells and human erythrocytes. J Clin Invest 68, 1305-1313.
17. Gnoth MJ, Kunz C, Kinne-Saffran E, et al. (2000) Human milk oligosaccharides are minimally digested in vitro. J Nutr 130, 3014-3020.
18. Engfer MB, Stahl B, Finke B, et al. (2000) Human milk oligo-saccharides are resistant to enzymatic hydrolysis in the upper gastrointestinal tract. Am J Clin Nutr 71, 1589-1596.
19. Coppa GV, Pierani P, Zampini L, et al. (2001) Characterization of oligosaccharides in milk and feces of breast-fed infants by high-performance anion-exchange chromato-graphy. Adv Exp Med Biol 501, 307-314.
20. Albrecht S, Schols HA, van Zoeren D, et al. (2011) Oligosaccharides in feces of breast-and formula-fed babies. Carbohydr Res 346, 2173-2181.
21. Kunz C, Rudloff S, Hintelmann A, et al. (1996) High-pH anion-exchange chromatography with pulsed amperometric detection and molar response factors of human milk oligo-saccharides. J Chromatogr B Biomed Appl 685, 211-221.
22. Diamond LS, Harlow DR & Cunnick CC (1978) A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba. Trans R Soc Trop Med Hyg 72, 431-432.
23. Mirelman D, Bracha R & Sargeaunt PG (1984) Entamoeba histolytica: virulence enhancement of isoenzyme-stable parasites. Exp Parasitol 57, 172-177.
24. Gillin FD & Diamond LS (1980) Attachment and short-term maintenance of motility and viability of Entamoeba histoly-tica in a defined medium. J Protozool 27, 220-225.
25. Gillin FD & Diamond LS (1980) Attachment of Entamoeba histolytica to glass in a defined maintenance medium: specific requirement for cysteine and ascorbic acid. J Proto-zool 27, 474-478.
26. Burchard GD, Prange G & Mirelman D (1993) Interaction between trophozoites of Entamoeba histolytica and the human intestinal cell line HT-29 in the presence or absence of leukocytes. Parasitol Res 79, 140-145.
27. Thurl S, Munzert M, Henker J, et al. (2010) Variation of human milk oligosaccharides in relation to milk groups and lactational periods. Br J Nutr 104, 1261-1271.
28. Coppa GV, Gabrielli O, Zampini L, et al. (2011) Oligosac-charides in 4 different milk groups, bifidobacteria, and Ruminococcus obeum.JPediatr GastroenterolNutr53, 80-87.
29. Ruiz-Palacios GM, Cervantes LE, Ramos P, et al. (2003) Campylobacter jejuni binds intestinal H(O) antigen (Fuc alpha 1, 2Gal beta 1, 4GlcNAc), and fucosyloligosaccharides of human milk inhibit its binding and infection. J Biol Chem 278, 14112-14120.
30. Morrow AL, Ruiz-Palacios GM, Altaye M, et al. (2004) Human milk oligosaccharides are associated with protection against diarrhea in breast-fed infants. J Pediatr 145, 297-303.
31. Rana SV, Bhasin DK & Vinayak VK (2004) Prospective evaluation of lactose malabsorption by lactose hydrogen breath test in individuals infected with Entamoeba histolytica and passing cysts. Br J Nutr 92, 207-208.