In vivo and in vitro cardiovascular effects of Papuan taipan (Oxyuranus scutellatus) venom: Exploring "sudden collapse"

Toxicology Letters

Volumn 213, Issue 2, 2012, Pages 243-248

  Chaisakul, Janeyuth ^a   Isbister, Geoffrey K ^a,b   Konstantakopoulos, Nicki ^a   Tare, Marianne ^a   Parkington, Helena C ^a   Hodgson, Wayne C ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

'Sudden collapse'; Anaesthetized rat; Cardiovascular collapse; Oxyuranus scutellatus; Papuan taipan venom

Indexed keywords

HEPARIN; INDOMETACIN; PAUPUAN TAIPAN VENOM; SNAKE VENOM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSE INCREASE; ENVENOMATION; HYPOTENSION; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; OXYYURANUS SCUTELLATUS; PAUPUAN TAIPAN; PRIORITY JOURNAL; RAT; SHOCK; SNAKE; SUDDEN COLLAPSE;

ANIMALS; AUSTRALASIA; CARDIOVASCULAR AGENTS; CARDIOVASCULAR SYSTEM; ELAPID VENOMS; HYPOTENSION; INDOMETHACIN; MALE; MESENTERIC ARTERIES; MUSCLE CONTRACTION; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; ELAPIDAE; OXYURANUS SCUTELLATUS; RATTUS;

EID: 84864465654     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.06.015     Document Type: Article

References (31)

1. Adams Z.S., Gattullo D., Losano G., Marsh N.A., Vacca G., Whaler B.C. The effect of Bitis gabonica (gaboon viper) snake venom on blood pressure, stroke volume and coronary circulation in the dog. Toxicon 1981, 19:263-270.
2. Barrett A.M. The effects of some autonomic blocking agents on the heart rates of anaesthetized and pithed rats. European Journal of Pharmacology 1971, 15:267-273.
3. Broad A.J., Sutherland S.K., Coulter A.R. The lethality in mice of dangerous Australian and other snake venom. Toxicon 1979, 17:661-664.
4. Catalan R.E., Aragones M.D., Martinez A.M., Armijo M., Pina M. Effect of indomethacin on the cyclic AMP-dependent protein kinase. European Journal of Pharmacology 1980, 63:187-190.
5. 2-induced hypotension in the rat and its pharmacological modulation. General Pharmacology 1993, 24:1197-1202.
6. Connolly S., Trevett A.J., Nwokolo N.C., Lalloo D.G., Naraqi S., Mantle D., Schofield I.S., Fawcett P.R., Harris J.B., Warrell D.A. Neuromuscular effects of Papuan Taipan snake venom. Annals of Neurology 1995, 38:916-920.
7. Crachi M.T., Hammer L.W., Hodgson W.C. A pharmacological examination of venom from the Papuan taipan: (Oxyuranus scutellatus canni). Toxicon 1999, 37:1721-1734.
8. Currie B.J. Snakebite in tropical Australia, Papua New Guinea and Irian Jaya. Emergency Medicine 2000, 12:285-294.
9. DalBo S., Moreira E.G., Brandao F.C., Horst H., Pizzolatti M.G., Micke G.A., et al. Mechanisms underlying the vasorelaxant effect induced by proanthocyanidin-rich fraction from Croton celtidifolius in rat small resistance arteries. Journal of Pharmacological Sciences 2008, 106:234-241.
10. 2 purified from various snake venoms. Proceedings of the National Science Council - Republic of China 1981, 5:181-189.
11. Hodgson W.C., Isbister G.K. The application of toxins and venoms to cardiovascular drug discovery. Current Opinion in Pharmacology 2009, 9:173-176.
12. 2 from Vipera russelli snake venom on blood pressure, plasma prostacyclin level and renin activity in rats. Toxicon 1984, 22:253-264.
13. Inase N., Schreck R.E., Lazarus S.C. Heparin inhibits histamine release from canine mast cells. American Journal of Physiology 1993, 264:L387-L390.
14. Ireland G., Brown S.G., Buckley N.A., Stormer J., Currie B.J., White J., Spain D., Isbister G.K. Changes in serial laboratory test results in snakebite patients: when can we safely exclude envenoming?. Medical Journal of Australia 2010, 193:285-290.
15. Isbister G.K., Williams V., Brown S.G., White J., Currie B.J. Clinically applicable laboratory end-points for treating snakebite coagulopathy. Pathology 2006, 38:568-572.
16. Johnston M.A., Fatovich D.M., Haig A.D., Daly F.F. Successful resuscitation after cardiac arrest following massive brown snake envenomation. Medical Journal of Australia 2002, 177:646-649.
17. Krstic M.K., Stepanovic' R., Ilic' K., Krstic' S.K. Endothelium-independent contractile and relaxant responses to histamine in the rabbit aorta and common carotid, mesenteric, renal, and femoral arteries. General Pharmacology: The Vascular System 1996, 27:529-533.
18. + channels via cyclic nucleotide-dependent protein kinases in mesenteric artery. Phytomedicine 2010, 17:760-770.
19. Marsh N.A., Smith I.C., Whaler B.C. Effects of envenomation on cardiac cell permeability [proceedings]. Journal of Physiology 1979, 291:72P-73P.
20. Myint L., Warrell D.A., Phillips R.E., Tin Nu S., Tun P., Maung Maung L. Bites by Russell's viper (Vipera russelli siamensis) in Burma: haemostatic, vascular, and renal disturbances and response to treatment. Lancet 1985, 2:1259-1264.
21. Parkington H.C., Chow J.A., Evans R.G., Coleman H.A., Tare M. Role for endothelium-derived hyperpolarizing factor in vascular tone in rat mesenteric and hindlimb circulations in vivo. Journal of Physiology 2002, 542:929-937.
22. Rash L.D., King R.G., Hodgson W.C. Evidence that histamine is the principal pharmacological component of venom from an Australian wolf spider (Lycosa godeffroyi). Toxicon 1998, 36:367-375.
23. 2) induces rapid depletion of cyclic AMP levels in brain nuclei of rats. Life Sciences 1987, 41:2547-2553.
24. Sket D., Gubensek F. Pharmacological study of phospholipase A from Vipera ammodytes venom. Toxicon 1976, 14:393-396.
25. Sutherland S.K., Campbell D.G., Stubbs A.E. A study of the major Australian snake venoms in the monkey (Macaca fascicularis). II. Myolytic and haematological effects of venoms. Pathology 1981, 13:705-715.
26. Tibballs J., Sutherland S., Kerr S. Studies on Australian snake venoms. Part 1: the haemodynamic effects of brown snake (Pseudonaja) species in the dog. Anaesthesia and Intensive Care 1989, 17:466-469.
27. Tibballs J., Sutherland S.K., Rivera R.A., Masci P.P. The cardiovascular and haematological effects of purified prothrombin activator from the common brown snake (Pseudonaja textilis) and their antagonism with heparin. Anaesthesia and Intensive Care 1992, 20:28-32.
28. Tibballs J., Sutherland S.K. The efficacy of heparin in the treatment of common brown snake (Pseudonaja textilis) envenomation. Anaesthesia and Intensive Care 1992, 20:33-37.
29. Vargas M., Segura A., Herrera M., Villalta M., Estrada R., Cerdas M., Paiva O., Matainaho T., Jensen S.D., Winkel K.D., Leon G., Gutierrez J.M., Williams D.J. Preclinical evaluation of caprylic acid-fractionated IgG antivenom for the treatment of Taipan (Oxyuranus scutellatus) envenoming in Papua New Guinea. PLoS Neglected Tropical Diseases 2011, 5:e1144.
30. Wickramaratna J.C., Fry B.G., Hodgson W.C. Species-dependent variations in the in vitro myotoxicity of death adder (Acanthophis) venoms. Toxicological Sciences 2003, 74:352-360.
31. Wuster W., Dumbrell A.J., Hay C., Pook C.E., Williams D.J., Fry B.G. Snakes across the Strait: trans-Torresian phylogeographic relationships in three genera of Australasian snakes (Serpentes: Elapidae: Acanthophis, Oxyuranus, and Pseudechis). Molecular Phylogenetics and Evolution 2005, 34:1-14.