Clinically applicable laboratory end-points for treating snakebite coagulopathy

Pathology

Volumn 38, Issue 6, 2006, Pages 568-572

  Isbister, Geoffrey K ^a,b   Williams, Vaughan ^c   Brown, Simon G A ^d   White, Julian ^e   Currie, Bart J ^a,f  

^a MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^b NEWCASTLE MATER HOSPITAL   (Australia)

^c WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e UNIVERSITY OF ADELAIDE   (Australia)

^f FLINDERS UNIVERSITY   (Australia)

Author keywords

Coagulation assays; Coagulopathy; Fibrinogen; Prothrombin activator; Snake bite

Indexed keywords

FIBRINOGEN; SNAKE VENOM ANTISERUM; VENOM ANTISERUM;

ADULT; ARTICLE; BLOOD CLOTTING DISORDER; BLOOD CLOTTING TEST; CONTROLLED STUDY; CONVALESCENCE; COST EFFECTIVENESS ANALYSIS; DISSEMINATED INTRAVASCULAR CLOTTING; FEMALE; FIBRINOGEN BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OUTCOME ASSESSMENT; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; SENSITIVITY ANALYSIS; SNAKE; SNAKEBITE; BIOASSAY; BLOOD; BLOOD CLOTTING; CLINICAL TRIAL; COST BENEFIT ANALYSIS; ECONOMICS; METABOLISM; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; PHYSIOLOGY; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY;

ADULT; ANTIVENINS; BLOOD COAGULATION; BLOOD COAGULATION TESTS; COST-BENEFIT ANALYSIS; ENDPOINT DETERMINATION; FEMALE; FIBRINOGEN; HUMANS; MALE; MIDDLE AGED; PARTIAL THROMBOPLASTIN TIME; PROSPECTIVE STUDIES; PROTHROMBIN TIME; SENSITIVITY AND SPECIFICITY; SNAKE BITES;

EID: 34247170477     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1080/00313020601024045     Document Type: Article

References (16)

1. Masci PP, Rowe EA, Whitaker AN, de Jersey J. Fibrinolysis as a feature of disseminated intravascular coagulation (DIC) after Pseudonaja textilis textilis envenomation. Thromb Res 1990; 59: 859-70.
2. Lalloo DG, Trevett AJ, Owens D, et al. Coagulopathy following bites by the Papuan taipan (Oxyuranus scutellatus canni). Blood Coagul Fibrinolysis 1995; 6: 65-72.
3. Isbister GK, Currie BJ, Little M, Daly FF, Isbister JP. Coagulopathy from tiger snake envenoming and its treatment. Pathology 2002; 34: 588-90.
4. Parkin JD, Ibrahim K, Dauer RJ, Braitberg G. Prothrombin activation in eastern tiger snake bite. Pathology 2002; 34: 162-6.
5. Currie BJ. Snakebite in tropical Australia, Papua New Guinea and Irian Jaya. Emerg Med 2000; 12: 285-94.
6. Sutherland SK, Tibballs J. Australian Animal Toxins. 2nd ed. Melbourne: Oxford University Press, 2001.
7. White J. Clinical toxicology of snakebite in Australia and New Guinea. In: Meier J, White J, editors. Handbook of Clinical Toxicology of Animal Venoms and Poisons. New York: CRC Press, 1995; 595-618.
8. St Pierre L, Masci PP, Filippovich I, et al. Comparative analysis of prothrombin activators from the venom of Australian elapids. Mol Biol Evol 2005; 22: 1853-64.
9. White J, Duncan B, Wilson C, Williams V, Lloyd J. Coagulopathy following Australian elapid snakebite: A review of 20 cases. In: Gopalakrishnakone P, Tan CK, editors. Recent Advances in Toxinology Research. Singapore: Venom and Toxin Research Group, National University Singapore, 1992; 337-44.
10. White J. Snakebite and Spiderbite - A Management Protocol for NSW. Sydney: NSW Health Department, 1997.
11. Mackie IJ, Kitchen S, Machin SJ, Lowe GD, Haemostasis and Thrombosis Task Force of the British Committee for Standards in Haematology, Guidelines on fibrinogen assays. Br J Haematol 2003; 121: 396-404.
12. Isbister GK, O'Leary MA, Schneider JJ, Brown SGA, Currie BJ. Estimation of brown snake antivenom dose in envenomed patients and with in vitro studies. International Congress of the European Association of Poison Centres and Clinical Toxicologists, Prague, April 18-21, 2006.
13. O'Leary MA, Isbister GK, Schneider JJ, Brown SG, Currie BJ. Enzyme immunoassays in brown snake (Pseudonaja species) envenoming: Detecting venom, antivenom and venom-antivenom complexes. Toxicon 2006; 48: 4-11.
14. Yeung JM, Little M, Murray LM, Jelinek GA, Daly FF. Antivenom dosing in 35 patients with severe brown snake (Pseudonaja) envenoming in Western Australia over 10 years. Med J Aust 2004; 181: 703-5.
15. Isbister GK, Currie BJ. Suspected snakebite: One year prospective study of emergency department presentations. Emerg Med (Fremantle) 2003; 15: 160-9.
16. Isbister GK, Hooper MR, Dowsett R, Maw G, Murray L, White J. Collett's snake (Pseudechis colletti) envenoming in snake handlers. QJM 2006; 99: 109-15.