Challenges and perspectives in anti-doping testing

Bioanalysis

Volumn 4, Issue 13, 2012, Pages 1691-1701

  Schamasch, Patrick ^a   Rabin, Olivier ^b  

^a Academic Medical Center VU University Medical Center   (Switzerland)

^b World Anti Doping Agency (WADA)   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHORIONIC GONADOTROPIN; CONTINUOUS ERYTHROPOIESIS RECEPTOR ACTIVATOR; PEPTIDE HORMONE; RECOMBINANT ERYTHROPOIETIN;

ACCREDITATION; ANALYTIC METHOD; BLOOD ANALYSIS; BLOOD TRANSFUSION; CHEMICAL ANALYSIS; COST CONTROL; DOPING; LABORATORY; LABORATORY TEST; LEGAL ASPECT; MASS SPECTROMETRY; REFERENCE VALUE; REVIEW; SENSITIVITY AND SPECIFICITY; SPORTS ORGANIZATION; STANDARD; URINALYSIS;

DESIGNER DRUGS; DOPING IN SPORTS; GENOMICS; HUMANS; INTERNATIONAL AGENCIES; LABORATORIES; PERFORMANCE-ENHANCING SUBSTANCES; PROTEOMICS; SPORTS; SUBSTANCE ABUSE DETECTION;

EID: 84864462465     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.145     Document Type: Review

References (14)

1. Conte V. BALCO: THE straight Dope on Steroids, Barry Bonds, Marion Jones and what we can do to save sports. Shyhorse Publishing, NY, USA (2008).
2. Catlin DH, Ahrens BD, Kucherova Y. Detection of norbolethone, an anabolic steroid never marketed, in athletes' urine. Rapid Commun. Mass Spectrom. 16(13), 1273-1275 (2002).
3. Catlin DH, Sekera MH, Ahrens BD, Starcevic B, Chang YC, Hatton CK. Tetrahydrogestrinone: Discovery, synthesis, and detection in urine. Rapid Commun. Mass Spectrom. 18(12), 1245-1049 (2004).
4. Sekera MH, Ahrens BD, Chang YC, Starcevic B, Georgakopoulos C, Catlin DH. Another designer steroid: Discovery, synthesis and detection of 'madol' in urine. Rapid Commun. Mass Spectrom. 19(6), 781-784 (2005).
5. Diel P, Friedel A, Geyer H et al. Characterisation of the pharmacological profile of desoxymethyltestosterone (Madol), a steroid misused for doping. Toxicol. Lett. 169(1), 64-71 (2007).
6. Lisi A, Hasick N, Kazlauskas R, Goebel C. Studies of methylhexaneamine in supplements and geranium oil. Drug Test. Anal. 3, 873-876 (2011).
7. Botrè FJ. New and old challenges of sports drug testing. Mass Spectrom. 43, 903-907 (2008).
8. Lasne F, De Ceaurriz J. Recombinant erythropoietin in urine. Nature 405(6787), 635 (2000).
9. Wu Z, Bidlingmaier M, Dall R, Strasburger CJ. Detection of doping with human growth hormone. Lancet 353(9156), 895 (1999).
10. Bidlingmaier M, Manolopoulou J. Detecting growth hormone abuse in athletes. Endocrinol. Metab. Clin. North Am. 39(1), 25-32 (2010).
11. Rabin O. Involvement of the health industry in the fight against doping in sport. Forensic Sci. Int. 213, 10-14 (2011).
12. Robinson N, Saugy M, Vernec A, Pierre- Edouard S. The Athlete Biological Passport: An effective tool in the fight against doping. Clin. Chem. 57(6), 830-832 (2011).
13. Beiter T, Zimmermann M, Fragasso A et al. Direct and long-term detection of gene doping in conventional blood samples. Gene Ther. 18(3), 225-231 (2011).
14. Ni W, Le Guiner C, Gernoux G, Penaud- Budloo M, Moullier P, Snyder RO. Longevity of rAAV vector and plasmid DNA in blood after intramuscular injection in nonhuman primates: Implications for gene doping. Gene Ther. 18(7), 709-718 (2011).