Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway

Journal of the American Chemical Society

Volumn 134, Issue 30, 2012, Pages 12402-12405

  Tibrewal, Nidhi ^a   Downey, Theresa E ^a   Van Lanen, Steven G ^a   Ul Sharif, Ehesan ^b   O'Doherty, George A ^b   Rohr, Jürgen ^a  

^a University of Kentucky   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHETIC PATHWAY; CATALYTIC CYCLES; HEMIACETALS; IN-VITRO; O-METHYLATION; O-METHYLTRANSFERASE; RECOMBINANT ENZYMES; S-ADENOSYLMETHIONINE;

ALKYLATION; BIOCHEMISTRY; CATALYSIS; ENZYMES; KETONES; PHENOLS;

BIOSYNTHESIS;

ANTINEOPLASTIC ANTIBIOTIC; FLAVINE ADENINE NUCLEOTIDE; GILVOCARCIN; HYDROQUINONE; METHYLTRANSFERASE; PROTEIN GILM; PROTEIN GILMT; QUINONE DERIVATIVE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DRUG SYNTHESIS; ENZYME PURIFICATION; IN VITRO STUDY; PROTEIN FUNCTION;

ANTIBIOTICS, ANTINEOPLASTIC; COUMARINS; GLYCOSIDES; METHYLATION; METHYLTRANSFERASES; OXIDATION-REDUCTION; RECOMBINANT PROTEINS; S-ADENOSYLMETHIONINE; STREPTOMYCES;

EID: 84864444670     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja305113d     Document Type: Article

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