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Volumn 27, Issue 7, 2012, Pages 2686-2693

Disintegration of colonic epithelial tight junction in uremia: A likely cause of CKD-associated inflammation

Author keywords

claudin; end stage renal disease; gastrointestinal tract; intestinal barrier defect; occludin

Indexed keywords

CLAUDIN 1; CREATININE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; OCCLUDIN; PROTEIN ZO1; UREA;

EID: 84864401998     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr624     Document Type: Article
Times cited : (249)

References (27)
  • 1
    • 77958516822 scopus 로고    scopus 로고
    • Inflammation in end-stage renal diseasewhat have we learned in 10 years?
    • Carrero JJ, Stenvinkel P. Inflammation in end-stage renal diseasewhat have we learned in 10 years?. Semin Dial 2010; 23: 498-509.
    • (2010) Semin Dial , vol.23 , pp. 498-509
    • Carrero, J.J.1    Stenvinkel, P.2
  • 2
    • 0036833743 scopus 로고    scopus 로고
    • The elephant in uremia: Oxidant stress as a unifying concept of cardiovascular disease in uremia
    • Himmelfarb J, Stenvinkel P, Ikizler TA et al. The elephant in uremia: oxidant stress as a unifying concept of cardiovascular disease in uremia. Kidney Int 2002; 62: 1524-1538.
    • (2002) Kidney Int , vol.62 , pp. 1524-1538
    • Himmelfarb, J.1    Stenvinkel, P.2    Ikizler, T.A.3
  • 3
    • 5444257487 scopus 로고    scopus 로고
    • Oxidative stress in uremia: Nature, mechanisms, and potential consequences
    • Vaziri ND. Oxidative stress in uremia: nature, mechanisms, and potential consequences. Semin Nephrol 2004; 24: 469-473.
    • (2004) Semin Nephrol , vol.24 , pp. 469-473
    • Vaziri, N.D.1
  • 4
    • 33846234740 scopus 로고    scopus 로고
    • Spontaneous leukocyte activation and oxygen-free radical generation in end stage renal disease
    • Yoon JW, Pahl MV, Vaziri ND. Spontaneous leukocyte activation and oxygen-free radical generation in end stage renal disease. Kidney Int 2007; 71: 167-172.
    • (2007) Kidney Int , vol.71 , pp. 167-172
    • Yoon, J.W.1    Pahl, M.V.2    Vaziri, N.D.3
  • 5
    • 74249111667 scopus 로고    scopus 로고
    • Effect of end stage renal disease and hemodialysis on expression and activities of leukocyte toll-like receptors (TLR)
    • Gollapudi P, Yoon JW, Gollapudi S et al. Effect of end stage renal disease and hemodialysis on expression and activities of leukocyte toll-like receptors (TLR). Am J Nephrol 2010; 31: 247-254.
    • (2010) Am J Nephrol , vol.31 , pp. 247-254
    • Gollapudi, P.1    Yoon, J.W.2    Gollapudi, S.3
  • 6
    • 33749631245 scopus 로고    scopus 로고
    • Associations between renal function, volume status and endotoxaemia in chronic kidney disease patients
    • Gonçalves S, Pecoits-Filho R, Perreto S et al. Associations between renal function, volume status and endotoxaemia in chronic kidney disease patients. Nephrol Dial Transplant 2006; 21: 2788-2794.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 2788-2794
    • Gonçalves, S.1    Pecoits-Filho, R.2    Perreto, S.3
  • 7
    • 42549129835 scopus 로고    scopus 로고
    • Endotoxemia is related to systemic inflammation and atherosclerosis in peritoneal dialysis patients
    • Szeto CC, Kwan BC, Chow KM et al. Endotoxemia is related to systemic inflammation and atherosclerosis in peritoneal dialysis patients. Clin J Am Soc Nephrol 2008; 3: 431-436.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 431-436
    • Szeto, C.C.1    Kwan, B.C.2    Chow, K.M.3
  • 8
    • 70449631288 scopus 로고    scopus 로고
    • Soluble CD14 levels, interleukin 6, and mortality among prevalent hemodialysis patients
    • Raj DS, Carrero JJ, Shah VO et al. Soluble CD14 levels, interleukin 6, and mortality among prevalent hemodialysis patients. Am J Kidney Dis 2009; 54: 1072-1080.
    • (2009) Am J Kidney Dis , vol.54 , pp. 1072-1080
    • Raj, D.S.1    Carrero, J.J.2    Shah, V.O.3
  • 9
    • 78651425794 scopus 로고    scopus 로고
    • Intestinal-renal syndrome: Mirage or reality?
    • Ritz E. Intestinal-renal syndrome: mirage or reality?. Blood Purif 2011; 31: 70-76.
    • (2011) Blood Purif , vol.31 , pp. 70-76
    • Ritz, E.1
  • 10
    • 0025147015 scopus 로고
    • Increased intestinal permeability to differently sized polyethylene glycols in uremic rats: Effects of low-and high protein diets
    • Magnusson M, Magnusson KE, Sundqvist T et al. Increased intestinal permeability to differently sized polyethylene glycols in uremic rats: effects of low-and high protein diets. Nephron 1990; 56: 306-311.
    • (1990) Nephron , vol.56 , pp. 306-311
    • Magnusson, M.1    Magnusson, K.E.2    Sundqvist, T.3
  • 11
    • 0025899472 scopus 로고
    • Impaired intestinal barrier function measured by differently sized polyethylene glycols in patients with chronic renal failure
    • Magnusson M, Magnusson KE, Sundqvist T et al. Impaired intestinal barrier function measured by differently sized polyethylene glycols in patients with chronic renal failure. Gut 1991; 32: 754-759.
    • (1991) Gut , vol.32 , pp. 754-759
    • Magnusson, M.1    Magnusson, K.E.2    Sundqvist, T.3
  • 13
    • 0021840133 scopus 로고
    • Pathology of gastrointestinal tract in chronic hemodialysis patients: An autopsy study of 78 cases
    • Vaziri ND, Dure-Smith B, Miller R et al. Pathology of gastrointestinal tract in chronic hemodialysis patients: an autopsy study of 78 cases. Am J Gastroenterol 1985; 80: 608-611.
    • (1985) Am J Gastroenterol , vol.80 , pp. 608-611
    • Vaziri, N.D.1    Dure-Smith, B.2    Miller, R.3
  • 14
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • Turner Jr. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009; 9: 799-809.
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 15
    • 40949108938 scopus 로고    scopus 로고
    • Tight junctions and the intestinal barrier
    • Burlington, MAElsevier Academic Press
    • Ma TYJohnson R. Tight junctions and the intestinal barrier. Textbook of Gastrointestinal Physiology 2006 Burlington, MAElsevier Academic Press
    • (2006) Textbook of Gastrointestinal Physiology
    • Ma, T.Y.1    Johnson, R.2
  • 16
    • 0033672942 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: Nutrients, cytokines, and immune cells
    • Nusrat A, Turner JR, Madara JL. Molecular physiology and pathophysiology of tight junctions. IV. Regulation of tight junctions by extracellular stimuli: nutrients, cytokines, and immune cells. Am J Physiol Gastrointest Liver Physiol 2000; 279: G851-G857.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Nusrat, A.1    Turner, J.R.2    Madara, J.L.3
  • 17
    • 2942675123 scopus 로고    scopus 로고
    • Downregulation of hepatic acyl-coa: Diglycerol acyltransferase (DGAT) in chronic renal failure
    • Vaziri ND, Dang B, Zhan CD et al. Downregulation of hepatic acyl-CoA: diglycerol acyltransferase (DGAT) in chronic renal failure. Am J Physiol Renal Physiol 2004; 287: F90-F94.
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Vaziri, N.D.1    Dang, B.2    Zhan, C.D.3
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta delta C(T))
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408.
    • (2001) Method. Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 63849337600 scopus 로고    scopus 로고
    • Mechanism of cytokine modulation of epithelial tight junction barrier
    • Al-Sadi R, Boivin M, Ma T. Mechanism of cytokine modulation of epithelial tight junction barrier. Frontiers Biosci 2009; 14: 2765-2778.
    • (2009) Frontiers Biosci , vol.14 , pp. 2765-2778
    • Al-Sadi, R.1    Boivin, M.2    Ma, T.3
  • 20
    • 33749007683 scopus 로고    scopus 로고
    • Inflammatory bowel disease and the apical junctional complex
    • Bruewer M, Samarin S, Nusrat A. Inflammatory bowel disease and the apical junctional complex. Ann N YAcad Sci 2006; 1072: 242-252.
    • (2006) Ann N YAcad Sci , vol.1072 , pp. 242-252
    • Bruewer, M.1    Samarin, S.2    Nusrat, A.3
  • 21
    • 33645824969 scopus 로고    scopus 로고
    • Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: Tight junction dynamics exposed
    • Shen L, Turner Jr. Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. Am J Physiol Gastrointest Liver Physiol 2006; 290: G577-G582.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290
    • Shen, L.1    Turner, J.R.2
  • 22
    • 79957938610 scopus 로고    scopus 로고
    • Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier
    • Al-Sadi R, Khatib K, Guo S et al. Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier. Am J Physiol Gastrointest Liver Physiol 2011; 300: G1054-G1064.
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.300
    • Al-Sadi, R.1    Khatib, K.2    Guo, S.3
  • 23
    • 77952536060 scopus 로고    scopus 로고
    • Segmental expression of claudin proteins correlates with tight junction barrier properties in rat intestine
    • Markov AG, Veshnyakova A, Fromm M et al. Segmental expression of claudin proteins correlates with tight junction barrier properties in rat intestine. J Comp Physiol B 2010; 180: 591-598.
    • (2010) J Comp Physiol B , vol.180 , pp. 591-598
    • Markov, A.G.1    Veshnyakova, A.2    Fromm, M.3
  • 24
    • 0033614672 scopus 로고    scopus 로고
    • Endotoxin and immune activation in chronic heart failure: A prospective cohort study
    • Niebauer J, Volk HD, Kemp M et al. Endotoxin and immune activation in chronic heart failure: a prospective cohort study. Lancet 1999; 353: 1838-1842.
    • (1999) Lancet , vol.353 , pp. 1838-1842
    • Niebauer, J.1    Volk, H.D.2    Kemp, M.3
  • 25
    • 80055027514 scopus 로고    scopus 로고
    • Studies on bacterial endotoxin and intestinal absorption function in patients with chronic heart failure
    • Sandek A, Bjarnason I, Volk HD et al. Studies on bacterial endotoxin and intestinal absorption function in patients with chronic heart failure. Int J Cardiol 2010;
    • (2010) Int J Cardiol
    • Sandek, A.1    Bjarnason, I.2    Volk, H.D.3
  • 26
    • 33947107619 scopus 로고    scopus 로고
    • Intestinal barrier dysfunction in developing liver cirrhosis: An in vivo analysis of bacterial translocation
    • Palma P, Mihaljevic N, Hasenberg T et al. Intestinal barrier dysfunction in developing liver cirrhosis: an in vivo analysis of bacterial translocation. Hepatol Res 2007; 37: 6-12.
    • (2007) Hepatol Res , vol.37 , pp. 6-12
    • Palma, P.1    Mihaljevic, N.2    Hasenberg, T.3
  • 27
    • 0028911902 scopus 로고
    • Diffusive and convective transfer of cytokine-inducing bacterial products across hemodialysis membranes
    • Pereira BJ, Snodgrass BR, Hogan PJ et al. Diffusive and convective transfer of cytokine-inducing bacterial products across hemodialysis membranes. Kidney Int 1995; 47: 603-610.
    • (1995) Kidney Int , vol.47 , pp. 603-610
    • Pereira, B.J.1    Snodgrass, B.R.2    Hogan, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.