Investigation on the oxidation of aryl oxiranylmethanols and the synthesis of 2-aryl-N-thiazolyl-oxirane-2-carboxamides as glucokinase activators

Tetrahedron Letters

Volumn 53, Issue 35, 2012, Pages 4738-4742

  Ye, Na ^a   Xu, Xiangtao ^b   Li, Fuying ^a   Ning, Mengmeng ^a   Liu, Zhiqing ^a   Cao, Yuqing ^b   Leng, Ying ^a   Zhang, Ao ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b HEBEI UNIVERSITY   (China)

Author keywords

Arylacetamides; Glucokinase activators; Oxo rearrangement; Ruthenium catalyzed

Indexed keywords

2 ARYL N THIAZOLYL OXIRANE 2 CARBOXAMIDE; ACETIC ACID; AMIDE; ARYL OXIRANYLMETHANOL; CARBOXYLIC ACID; METHANOL; OXIRANECARBOXAMIDE; PHOSPHOTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ASSAY; OXIDATION; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 84864401430     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2012.06.111     Document Type: Article

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